Use of Electrocardiographic Markers to Predict Ventricular Arrhythmias in Acute Myocarditis Patients

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dc.contributor.authorYumurtacı, Öznur
dc.contributor.authorKurt, Cansu
dc.contributor.authorUçar, Fatih Mehmet
dc.contributor.authorÖztürk, Cihan
dc.date.accessioned2021-11-20T10:26:28Z
dc.date.available2021-11-20T10:26:28Z
dc.date.issued2017
dc.departmentFakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, İç Hastalıkları Anabilim Dalıen_US
dc.departmentFakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Kardiyoloji Anabilim Dalıen_US
dc.description.abstractAims: Acute myocarditis is an inflammatory disease of the myocardium and is characterized by a large heterogeneity of clinical presentation. Myocarditis is becoming to be recognized as a contributor to unexplained mortality, and is thought to be a major cause of sudden cardiac death in the first two decades of life. Myocardial inflammation, ion channel dysfunction, electrophysiological and structural remodelling may play important roles in life-threatening arrhythmias. We aimed to investigate the ventricular arrhythmia predictors in myocarditis patients by using electrocardiographic markers. Methods: A total of 56 patients (mean age 22.5 ± 3.7 years; 89% males) with acute myocarditis were enrolled in the study. Tpeak-Tend intervals, Tpeak-Tend/QT and Tpeak-Tend/corrected QT (QTc), cardio-electrophysiological balance (QT/QRS) and heart rate-corrected QT(QTc)/QRS ratios were calculated from 12-lead electrocardiogram. Results: Heart rate, QT and QTc values were similar between groups. QRS complexes were lower in arrhythmia positive group than arrhythmia negative group (p=0.004). Tpeak-Tend intervals, Tpeak-Tend/QT, Tpeak-Tend/ QTc, cardio-electrophysiological balance and heart rate-corrected QT(QTc)/QRS values were significantly higher in arrhythmia positive group ( lt; 0.001, lt; 0.001, p=0.03, p=0.04 and lt; 0.001, respectively). Conclusion: In this study, we observed that higher Tpeak-Tend, Tpeak-Tend/QT, Tpeak-Tend/QTc , cardio-electrophysiological balance (ICEB) and heart rate-corrected QT(QTc)/QRS ratio are associated with ventricular arrhythmic episodes in acute myocarditis patients. These electrocardiographic markers may be beneficial to identify high risk patients for arrhytmias complicating myocarditis.en_US
dc.identifier.dergipark379058en_US
dc.identifier.endpage10en_US
dc.identifier.issn2148-4724
dc.identifier.issn2548-0030
dc.identifier.issue1en_US
dc.identifier.startpage6en_US
dc.identifier.urihttps://dergipark.org.tr/tr/pub/tmsj/issue/34305/379058
dc.identifier.urihttps://dergipark.org.tr/tr/download/article-file/404692
dc.identifier.urihttps://hdl.handle.net/20.500.14551/6061
dc.identifier.volume4en_US
dc.language.isoenen_US
dc.publisherTrakya Üniversitesien_US
dc.relation.ispartofTurkish Medical Student Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectArrhythmiaen_US
dc.subjectelectrocardiographyen_US
dc.subjectmyocarditisen_US
dc.titleUse of Electrocardiographic Markers to Predict Ventricular Arrhythmias in Acute Myocarditis Patientsen_US
dc.typeArticleen_US

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