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Öğe Successful Management of Peripartum Cardiomyopathy in a Young Female Patient(Trakya Üniversitesi, 2021) Yüksel, Ceren; Çıray, Bengisu; Koşucu, Mustafa Alperen; Altay, ServetAims: Peripartum cardiomyopathy is a rarely seen pregnancy-related myocardial disorder. The diagnosis is usually challenging and is made by exclusion. We aimed to present the recovery of a patient with peripartum cardiomyopathy as a result of a successful treatment plan. Case Report: A 26-year-old female patient with type-2 diabetes mellitus presented to the cardiology department of Trakya University School of Medicine. The patient experienced dyspnea and edema after delivery at 37 weeks of gestation. After the results of the blood tests, further cardiac examinations were deemed necessary. The echocardiogram revealed a low ejection fraction, indicating heart failure. The patient was recommended to halt breastfeeding and bromocriptine treatment was started. The patient was discharged one week later and kept under follow-up. Conclusion: Peripartum cardiomyopathy is a rare disease and therefore not easy to diagnose, but with appropriate treatment plans and frequent follow-ups, patients have high chances of full recovery.Öğe Evaluation of Malnutrition Statuses in Systolic Heart Failure Patients(Trakya Üniversitesi, 2019) Özyiğit, İrmak İrem; Koçyiğit, Beliz; Söyleyici, Begüm; Uçar, Fatih MehmetAims: The aim of this study is to determine the malnutrition statuses of patients with systolic heart failure in Trakya University Hospital and Edirne Sultan 1st Murat State Hospital.Methods: Mini Nutritional Assessment was used to determine the patients’ malnutrition statuses. In addition, patients’ transthoracic echocardiography results, biochemistry tests, hemograms, medications and habits were evaluated with patients’ nutritional scores. One-way ANOVA and Kruskal-Wallis tests were used for comparing the results and Pearson?2 test and Fischer’s exact test were used to obtain categorical data. Results: The total number of subjects in the study was 66 (61 patients from Trakya University Hospital; 5 patients from Edirne Sultan 1st Murat State Hospital). The mean age of all subjects was 65.3 ± 11.1. Out of all patients, 17 of them were female, while 49 of them were male. The mean Mini Nutrition Assessment score was 21.9 ± 4.7. In total, 34 patients had an adequate nutritional status, 25 patients were at risk of malnutrition and 7 patients were malnourished. Conclusion: Although malnourished patients were detected, well – nourished patients were higher. Therefore, it could be said that patients with heart failure are conscious of their health and diet. It is crucial for the health care providers to maintain giving advices on healthy living and nutrition to keep this elderly population well–nourishedÖğe Evaluation of Demographic, Clinic and Genetic Characteristics of Patients Admitted to Trakya University Hospital With Hypertrophic Cardiomyopathy(Trakya Üniversitesi, 2021) Bardakçı, Burak; Tan, Berfin; Kızılkaya, Sarper; Yüksel, Ceren; Altay, ServetAims: This study aims to evaluate the genetics, clinical characteristics, and functional abnormalities of patients diagnosed with hypertrophic cardiomyopathy in Trakya University Hospital. Methods: This retrospective study was conducted with patients who were diagnosed with hypertrophic cardiomyopathy between November 2009 - November 2019 in Trakya University Hospital. The data were obtained from the hospital’s database. Patients’ data (regarding age, gender, ge- netics, transthoracic echocardiogram findings, medications, types of hypertrophic cardiomyopathy, and first diagnoses) were examined. Numbers, percentages, means, and standard deviations were used as descriptive statistics. Results: Eleven patients with hypertrophic cardiomyopathy were evaluated. Five (45.45%) were female and 6 (54.54%) were male. The mean age of the female patients was 58.20 ± 8.57 years. The most common type of hypertrophic cardiomyopathy was found to be asymmetrical septal cardiomyopathy [7 (63.63%)]. Three (27.27%) patients presented with hypertension. There were gene mutations in three patients. Among these three patients, two (18.18%) patients have MYBPC3, and one (9.09%) patient has TTN gene mutations. Conclusion: Hypertrophic car- diomyopathy is usually accompanied by comorbidities such as arrhythmias, myocardial infarction, coronary artery disease. Therefore, these patients must be paid attention to in these matters.Öğe Arrow Cause of Angina Pectoris: Single Coronary Artery Anomaly in Elderly Patient(Trakya Üniversitesi, 2020) Göztepe, Aslı; Altay, ServetAims: Coronary artery anomalies are rare diseases among the population. These anomalies, which are usually noticed by chance, can remain silent for many years without symptoms. We aimed to present a patient with a coronary artery anomaly withouthaving any symptoms for many years. Case Report: A 73-year-old female patient presented to the Department of Cardiologyof the Trakya University School of Medicine. The patient stated that she had chest pain that decreased with rest and increasedwith exercise for the last 2 months. After the cardiac examination of the patient, imaging procedures were deemed necessary.After imaging, the patient was diagnosed with a single coronary artery anomaly. The patient was recommended to have surgery,but she refused. Upon this, the patient was discharged on condition that she was kept under frequent follow-up. Conclusion:Coronary artery anomalies have reached higher rates of diagnosis thanks to increased imaging technologies in recent years. Ifthese congenital diseases that can even cause death are noticed early, there are various treatment options. First of all, medicaltreatment is preferred, and surgery is recommended in patients with no response to the medical treatment. This disease, whichis closely related to the patient's life, should be carefully evaluated by the doctors. Keywords: Coronary arteries, cardiac anomaly,angiographyÖğe Hydatid Cyst in a Heart Failure Patient Mimicking Phantom Tumor(Trakya Üniversitesi, 2021) Özyiğit, Irmak; Koçyiğit, Beliz; Altay, ServetAims: We aimed to present a heart failure patient with a hydatid cyst of the lung, mimicking a phantom tumor. Case Report: A 71-year-old male patient pre- sented to the cardiology department of Trakya University School of Medicine with increasing shortness of breath and cough. His hospital admission complaints, heart failure history, and chest radiology results were consistent with a phantom tumor of the lung secondary to congestive heart failure. The patient was given diuretics; however, there was no evidence of resolution or change in the size of the observed cystic lesion. A hydatid cyst as a differential diagnosis was consid- ered, and subsequent questioning of the patient revealed animal contacts. The patient was offered the option of surgical removal of the cyst, which he declined due to the high mortality risk. The patient was prescribed 400 mg of albendazole and was advised to have regular check-ups. In the long term, he showed no further signs and symptoms of hydatid cyst. The hydatid cyst was neither removed nor disappeared, and it continued to be visible on radiological follow-up examinations. Conclusion: Due to the similarities present in admission complaints and chest examinations, it is challenging to differentiate hydatid cyst of the lung in heart failure patients. Physicians should be aware of the hydatid cyst in the differential diagnosis of pleural cysts and consider patients’ occupation and residency in order to not overlook zoonotic diseases.Öğe Constrictive Pericarditis: An Overlooked Cause of Ascites(Trakya Üniversitesi, 2021) Koçyiğit, Beliz; Özyiğit, Irmak; Altay, ServetAims: Constrictive pericarditis is a well-known but unusual and rare cause of ascites. The diagnosis of constrictive pericarditis in most patients who have chronic ascites is challenging. We aimed to present a patient with constrictive pericarditis with chronic ascites and pericardial calcifications seen in chest radiography. Case Report: A 66-year-old male patient presented to the emergency room of Trakya University School of Medicine. The patient had abdominal swelling and ascites for the last 5 years and underwent large-volume paracentesis in his previous emergency admissions. After the electrocardiography of the patient, he was directed to the cardiology department for further examinations. The chest radiography revealed significant pericardial calcifications. Following imaging procedures confirmed radiological findings, and the patient was diagnosed with constrictive pericarditis. Furthermore, his cardiac catheterization findings were consistent with constrictive pericarditis. The patient was recommended to have a pericardiectomy operation and there was a significant reduction in the patient's symptoms after surgery. Conclusion: The absence of specific symptoms and resemblances of existing symptoms to liver disease make the early diagnosis of con- strictive pericarditis difficult. Physicians should consider constrictive pericarditis as a differential diagnosis when dealing with a patient who has chronic ascites.Öğe A Case Report of Spontaneous Coronary Artery Dissection(Trakya Üniversitesi, 2018) Özdemir, Yusuf Can; Elmacı, Kubilay; Özçelik, FatihAims: Spontaneous coronary artery dissection is a random rupture of the coronary artery wall, which may leadto ischemia of the heart tissue. 30% of the cases are male patients. The aim of this article is to report a patient withspontaneous coronary artery dissection, raise awareness and extend the literature.Case Report: A 43-year-old male patient was presented to Trakya University Hospital with a complaint of persistentchest pain. The patient underwent coronary angiography, revealing spontaneous coronary artery dissection inthe left anterior descending artery and circumflex artery.Conclusion: In this case report, we demonstrated the diagnosis of spontaneous coronary artery dissection withcoronary angiography. Our patient had the most common dissection, left anterior descending artery, right coronaryartery and left main coronary artery. Only medical therapy could be started for the patient due to his voluntary discharge.Öğe Use of Electrocardiographic Markers to Predict Ventricular Arrhythmias in Acute Myocarditis Patients(Trakya Üniversitesi, 2017) Yumurtacı, Öznur; Kurt, Cansu; Uçar, Fatih Mehmet; Öztürk, CihanAims: Acute myocarditis is an inflammatory disease of the myocardium and is characterized by a large heterogeneity of clinical presentation. Myocarditis is becoming to be recognized as a contributor to unexplained mortality, and is thought to be a major cause of sudden cardiac death in the first two decades of life. Myocardial inflammation, ion channel dysfunction, electrophysiological and structural remodelling may play important roles in life-threatening arrhythmias. We aimed to investigate the ventricular arrhythmia predictors in myocarditis patients by using electrocardiographic markers. Methods: A total of 56 patients (mean age 22.5 ± 3.7 years; 89% males) with acute myocarditis were enrolled in the study. Tpeak-Tend intervals, Tpeak-Tend/QT and Tpeak-Tend/corrected QT (QTc), cardio-electrophysiological balance (QT/QRS) and heart rate-corrected QT(QTc)/QRS ratios were calculated from 12-lead electrocardiogram. Results: Heart rate, QT and QTc values were similar between groups. QRS complexes were lower in arrhythmia positive group than arrhythmia negative group (p=0.004). Tpeak-Tend intervals, Tpeak-Tend/QT, Tpeak-Tend/ QTc, cardio-electrophysiological balance and heart rate-corrected QT(QTc)/QRS values were significantly higher in arrhythmia positive group ( lt; 0.001, lt; 0.001, p=0.03, p=0.04 and lt; 0.001, respectively). Conclusion: In this study, we observed that higher Tpeak-Tend, Tpeak-Tend/QT, Tpeak-Tend/QTc , cardio-electrophysiological balance (ICEB) and heart rate-corrected QT(QTc)/QRS ratio are associated with ventricular arrhythmic episodes in acute myocarditis patients. These electrocardiographic markers may be beneficial to identify high risk patients for arrhytmias complicating myocarditis.Öğe Impact of T Wave Amplitude in Lead Avr on Predicting Appropriate Therapies in Hypertrophic Cardiomyopathy Patients With An Implantable Cardioverter Defibrillator(Trakya Üniversitesi, 2018) Söyleyici, Begüm; Hünkar, Pelinsu Elif; Girit, Çağrı; Kurt, Cansu; Uçar, Fatih MehmetAims: Although implantable cardioverter defibrillator reduces mortality in hypertrophic cardiomyopathy patients,inappropriate implantable cardioverter defibrillator shocks are related to increased mortality. The aim of this studyis to investigate whether a new electrocardiographic marker of T wave amplitude in lead aVR can be used to predictappropriate therapy of implantable cardioverter defibrillator (shock or anti-tachycardia pacing) in hypertrophic cardiomyopathypatients.Methods: Thirty-six hypertrophic cardiomyopathy patients, who were admitted to the outpatient clinic for pacemakercontrol, with implantable cardioverter defibrillator were retrospectively examined (mean age: 51 ± 10.2 years,72.2% male). The primary endpoint was appropriate implantable cardioverter defibrillator therapy. All hematological,biochemical and electrocardiogram parameters were measured before implantable cardioverter defibrillator wasimplanted.Results: Over a median follow-up period of 33 months, 9 (25%) patients experienced appropriate implantablecardioverter defibrillator therapy. Heart rate and QRS interval were similar between groups. QT and QTc valueswere higher in patients that received appropriate shocks. Patients who have T wave inversion were higher in therapypositive group. T wave amplitude in lead aVR values were significantly associated with appropriate therapy.Conclusion: Using simple ECG parameters, we may predict arrhythmic episodes before ICD implantation and animprovement of the medical antiarrhythmic therapy might be protective for HCM patients with ICD.Öğe Reverse McConnell sign in a patient with acute pulmonary embolism(2010) Tatlı, Ersan; Aktöz, Meryem; Yel, Mesih; Önal, Barış; Altun, ArmağanPulmoner embolinin tanısı için birçok ekokardiyografik parametre bulunmaktadır. Bu parametreler arasında, sağ ventrikül apikal kasılması normalken sağ ventrikül serbest duvar hareketinde hipokinezi olması “McConnell bulgusu” olarak tanımlanmaktadır. Biz sağ ventrikül apeksi ve serbest duvarının reversibl akinezisine yol açan akut pulmoner embolili bir olgu sunduk ve bu bulguyu “ters McConnell işareti” olarak yorumladık.Öğe A patient with unstable angina and without abnormal electrocardiographic findings and total occlusion of the left anterior descending coronary artery(2010) Tatlı, Ersan; Aktöz, Meryem; Altun, ArmağanKoroner kollateraller koroner anjiyografide görülebilir ve yeterli kan akımını sağlamak için damar yetersiz kaldığında önemli bir alternatif kaynak olarak görev alırlar. Biz sol ön inen koroner arteri tam tıkanmış, anstabil anginalı ve normal elektrokardiyografi bulgularına sahip bir hasta rapor ediyoruz.Öğe Effect of carvedilol on P-wave duration and P-wave dispersion in patients with systolic heart failure(2009) Tatlı, Ersan; Aktöz, Meryem; Barutçu, Ahmet; Kürüm, Turhan; Altun, ArmağanAmaç: Karvedilol tedavisi, sol ventrikül ejeksiyon fraksiyonunu artırır, ventriküler disfonksiyonun şiddetini, morbidite ve mortaliteyi azaltır. Ancak sistolik kalp yetmezlikli hastalarda karvedilolün P dalga dispersiyonu ve süresi üzerine etkileri bilinmemektedir. Bu çalışmada kalp yetmezliği olan hastalarda karvedilolün P dalga süresi ve dispersiyonu üzerine olan etkilerini araştırdık. Hastalar ve Yöntemler: Sol ventrikül ejeksiyon fraksiyonu %40'ın altında olan kalp yetmezlikli 56 hasta ileriye dönük olarak çalışmaya alındı. Karvedilol kalp yetmezliğinin standart tedavisine ek olarak verildi. Başlangıçta ve karvedilol tedavisinin dördüncü ayında fizik muayene, radyonüklid çalışma ve başlangıç maksimum ve minimum P-dalga süresi ve P-dalga dispersiyonu ölçümleri yapıldı. Bulgular: Karvedilol tedavisi ile maksimum P dalga süresi ve P-dalga dispersiyonu belirgin olarak azaldı. Sol ventrikül ejeksiyon fraksiyonu ve NYHA fonksiyonel sınıfı karvedilol tedavisi sonrası düzeldi. (Maksimum P-dalga süresi; 126±9 ms'den 120±7ms'ye; p=0.001, P- dalga dispersiyonu; 51±7 ms'den 46±5 ms'ye geriledi; p=0.001). Sonuç: Karvedilol tedavisi maksimum P-dalga süresi ve P-dalga dispersiyonunu direkt (doğrudan) ve indirekt (dolaylı) olarak azaltır. Bu kalp yetmezliği olan hastalarda atriyal fibrilasyon görülme sıklığını azaltabilir.Öğe Abrupt vessel occlusion during intracoronary intervention: Is this nightmare related to contrast agent?(2008) Tatlı, Ersan; Aktoz, Meryem; Ufacık, Osman; Pirhan, Osman; Yılmaztepe, Mustafa; Altun, ArmağanKırk altı yaşında, koroner arter hastalığı için risk faktörü olarak hipertansiyon ve aile öyküsü olan erkek hasta akut anterior miyokard infarktüsünün ikinci saati içinde kliniğimize başvurdu. Kurtarıcı perkütan koroner girişim sırasında sol ön inen arterin tam tıkandığı gözlendi. İşlem sırasında kullanılan 150 ml non-iyonik, düşük osmolar kontrast maddenin trombüse yol açarak tam tıkanıklığa neden olabileceği düşünüldü. İntrakoroner bolus tirofiban infüzyonu sonrasında intrakoroner trombozun çözüldüğü görüldü. Lezyon bölgesine stent uygulandı ve TIMI III akımla birlikte çok iyi anjiyografik sonuç elde edildi. Beş ay sonra yapılan kontrol anjiyografide sol ön inen koroner arter tamamen açık idi. Kurtarıcı işlem sırasında gelişen akut koroner tıkanmaların tedavisinde tirofiban infüzyonuyla bareber stentleme tıkanıklığı etkin bir şekilde gidermektedir.Öğe Perikardiyal tamponad kliniği ile gelen tip A aort diseksiyon olgusuna acil yaklaşım(2007) Ordulu, Emine; Erdoğan, OkanAltmış sekiz yaşındaki erkek hasta ani başlayan göğüs ve sırt ağrısını takiben gelişen, geçici bilinç kaybı ile acil polikliniğimize başvurdu. Fizik bakıda baş ve boyun bölgesinde belirgin siyanoz, boyun ven distansiyonu bulunan hastanın ekokardiyografisinde kalp boşlukları çevresinde yoğun içerikli sıvı görüldü. Kontrastlı torakoabdominal bilgisayarlı tomografide diseksiyon lehine bulgu saptanamadı. Perikardiyal tüp drenajı ile 650 cc sıvı boşaltılan hastanın klinik durumu belirgin olarak düzeldi. Tekrarlanan ekokardiyografide çıkan aortta, kapak seviyesinden 2 cm proksimalde başlayan hipodens alanın ayırdığı çift kontur görünümü saptandı. Hasta ameliyata alındı, çıkan aorta kapak seviyesinden 2 cm proksimalden itibaren 6 cm'lik segment boyunca Dacron greft yerleştirildi ve şifa ile taburcu edildi.Öğe Are Female Patients More Overlooked in the Diagnosis of Fabry Disease?(2020) Gürdoğan, Muhammet; Akkuş, Ömer Ferudun[Abtract Not Available]Öğe A Spider in the Spider’s View: Behçet’s Disease-related Giant Coronary Aneurysm(2020) Altay, Servet; Gürdoğan, Muhammet; Yılmaztepe, Mustafa Adem[Abtract Not Available]Öğe Layer-specific strain analysis in patients with suspected stable angina pectoris and apparently normal left ventricular wall motion(BMC, 2018) Yilmaztepe, Mustafa Adem; Ucar, Fatih MehmetBackground: Non-invasive imaging tests are widely used in the evaluation of stable angina pectoris (SAP). Despite these tests, non-significant coronary lesions are not a rare finding in patients undergoing elective coronary angiography (CAG). Two-dimensional (2D) speckle tracking global longitudinal strain (GLS) imaging is a more sensitive and accurate technique for measuring LV function than conventional 2D methods. Layer-specific strain analysis is a relatively new method that provides endocardial and epicardial myocardial layer assessment. The aim of the present study was to evaluate longitudinal layer-specific strain (LSS) imaging in patients with suspected SAP. Methods: Patients who underwent CAG for SAP were retrospectively screened. A total of 79 patients with no history of heart disease and wall motion abnormalities were included in the study. Forty-three patients with coronary lesions > 70% constituted the coronary artery disease (CAD) group and 36 patients without significant CAD constituted the control group. Layer-specific GLS transmural, endocardium, and epicardium values (GLS-trans, GLS-endo, and GLS-epi, respectively) were compared between the groups. Results: Patients in the CAD group had significantly lower GLS values in all layers (GLS-trans: -18.2 + 2.4% vs -22.2 + 2.2% p <.001; GLS-endo: -20.8 + 2.8% vs -25.3 + 2.6%, p < .001; GLS-epi: 15.9 + 2.4% vs -19.5 + 1.9%, p < .001). Multivariate adjustment demonstrated GLS-trans as the only independent predictor of CAD (OR:0.472, CI (0.326-0.684), p < .001]. Additionally, the GLS values were all lower in myocardial perfusion scintigraphy (MPS) true-positive patients compared with MPS false-positive patients (GLS-trans: -17.7 +/- 2.4 vs. -21.9 +/- 2.4%, p < .001; GLS-endo: -20.2 +/- 2.9% vs -24.9 +/- 2.9%, P < .001; GLS-epi: 15.4 +/- 2.6% vs. -19.2 +/- 1.8%, P < .001). Conclusion: Resting layer-specific strain as assessed by 2D speckle tracking analysis demonstrated that GLS values were reduced in all layers of myocardium with SAP and with no wall motion abnormalities. LSS analysis can improve the identification of patients with significant CAD but further prospective larger scale studies are needed to put forth the incremental value of LSS analysis over transmural GLS.Öğe Effect of transient ulnar artery compression on radial artery diameter(SPANDIDOS PUBL LTD, 2018) Yilmaztepe, Mustafa Adem; Yilmaz, ErdemThe transradial approach is widely preferred in coronary procedures. A small radial artery diameter (RAD) is the most important factor affecting successful access. Various maneuvers and medications have been used to increase the RAD and thereby facilitate RA cannulation. Ulnar artery compression (UAC) for 30 min has been indicated to be effective in increasing the RAD and facilitating RA access. The aim of the present preliminary study was to assess the effect of transient UAC for 1 min on the RAD. A total of 151 patients were included in the present study. RA ultrasonography was performed at the level of the wrist. The UA was compressed for 1 min. The RAD was measured at baseline, at the end of UAC and at 1 min thereafter. The results indicated that the RAD was significantly smaller in diabetic vs. non-diabetic patients (2.35 +/- 0.43 vs. 2.50 +/- 0.39 mm, P=0.024) and in women vs. men (2.25 +/- 0.38 vs. 2.56 +/- 0.38 mm, P<0.001). At the end of UAC, the RAD was increased compared with that at baseline (2.45 +/- 0.41 vs. 2.62 +/- 0.41 mm, P<0.001), but it started to decrease thereafter, and the RAD measured at 1 min after stopping UAC was significantly smaller (2.62 +/- 0.41 vs. 2.55 +/- 0.40 mm, P<0.001), while remaining significantly larger than that at baseline (P<0.001). The RA peak systolic flow velocity also increased significantly during UAC (35.3 +/- 8.9 vs. 60.3 +/- 19.2 cm/sec; P<0.001). In conclusion, Transient UAC for 1 min significantly increased the RAD and the peak systolic flow velocity. Further studies with clinical endpoints are required for further exploration of the feasibility of this approach.Öğe High-Normal Thyroid-Stimulating Hormone in Euthyroid Subjects is Associated with Risk of Mortality and Composite Disease Endpoint only in Women(TERMEDIA PUBLISHING HOUSE LTD, 2018) Altay, Servet; Onat, Altan; Can, Gunay; Tusun, Eyyup; Simsek, Baris; Kaya, AdnanIntroduction: The aim of the study was to evaluate whether serum thyroid-stimulating hormone (TSH) within the normal range in euthyroid subjects (having normal free triiodothyronine (fT3) and thyroxine (fT4)) is related to the risk of overall mortality or a composite endpoint of death and nonfatal events. Material and methods: In 614 middle-aged adult hospital screenees, free of uncontrolled diabetes at baseline, the association of sex-specific TSH tertiles with death was prospectively assessed using Cox regression, with the composite endpoint assessed using logistic regression in adjusted analyses, stratified by gender. Results: In total, 64 deaths and additional incident nonfatal events in 141 cases were recorded at a mean 7.55 years' follow-up. Multivariable linear regression revealed TSH to be significantly associated among men with age (p = 0.006), but in women inversely with fT3 and fT4 (p < 0.001, and p = 0.024 respectively). In logistic regression analysis, adjusted for age, fT3, fT4, systolic blood pressure and serum total cholesterol, sex-specific baseline TSH tertiles were associated in men neither with the risk of death nor with composite endpoint. In contrast, in women, the highest compared with the bottom TSH tertile predicted the risk of composite endpoint (relative risk: 2.02, 95% CI: 1.07-3.82) and, much more strongly, the mortality risk, independently of fT4 increments. Conclusions: The significant association of higher range of normal serum TSH in euthyroid middle-aged adults with the risk of death and nonfatal adverse outcomes in women alone cannot be accounted for by the action of thyroid hormone and is consistent with involvement of TSH in the pro-inflammatory state.Öğe What is the association between obesity and diastolic dysfunction: Obesity or obesity phenotype?(Turkish Soc Cardiology, 2018) Altay, ServetObesity is currently one of the greatest public health issues worldwide. It is associated with several alterations in cardiac morphology and ventricular function. Left ventricular diastolic dysfunction occurs commonly in obese individuals, particularly the severely obese and the hypertensive obese. The influence on diastolic function seems to be multifactorial and may be a result of effects of adipose tissue as well as obesity-related comorbidities.
