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Öğe Adding magnesium to lidocaine for intravenous regional anesthesia(Lippincott Williams & Wilkins, 2004) Turan, A.; Memis, D.; Karamanlyoglu, B.; Guler, T.; Pamukcu, Z.[Abstract Not Available]Öğe Comparison of dexmedetomidine with midazolam in premedication(Lippincott Williams & Wilkins, 2004) Kaya, G.; Turan, A.; Cetinaslan, O.; Pamukcu, Z.; Turan, N.[Abstract Not Available]Öğe Comparison of propofol and dexmedetomidine in monitored anesthesia care of ear-nose-throat surgery(Lippincott Williams & Wilkins, 2004) Turan, A.; Sapolyo, O.; Karamanlioglu, B.; Kurt, I.; Pamukcu, Z.[Abstract Not Available]Öğe A comparison of the effect on gastric emptying of propofol or dexmedetomidine in critically ill patients(Cambridge Univ Press, 2006) Memis, D.; Dokmeci, D.; Karamanlioglu, B.; Turan, A.; Ture, M.Background: Propofol and dexmedetomidine are widely used for sedation in the intensive care unit yet there are limited data on its effects on gastric motility. In our preliminary study, we examined whether or not any effect of propofol and dexmedetomidine on gastric emptying is preserved in critically ill patients. Methods: Twenty-four critically ill, enterally fed adult patients each received enteral feeding via a nasogastric tube at 50 mL h(-1) throughout the 5-h study period. Either propofol 2 mg kg(-1) h(-1) (n = 12, Group P) or dexmedetomidine 0.2 mu g kg(-1) h(-1) (n = 12, Group D) was given intravenously over 5h. Gastric motility was measured indirectly by analysis of the absorption over time of 1.5 g of paracetamol administered into the stomach at the start of the study period. At the beginning and end of the study, residual gastric volume and pH of residual gastric fluid were measured. Results: Gastric residual volume measured at the end of propofol infusion (19.33 +/- 11.33) was found to be higher when compared with the volume measured before infusion (11.33 +/- 4.84) and after dexmedetomidine infusion (9.17 +/- 4.54). But, there was no difference between groups in gastric emptying time (AUC120 894.53 +/- 499.39 vs. 1113.46 +/- 598-09 propofol and dexmedetomidine groups, respectively). Conclusion: In our study, gastric residual volume measured at the end of propofol infusion was found to be higher when compared with the volume measured before infusion and after dexmedetomidine infusion. There was no difference between groups in gastric emptying time.Öğe Comparison of the laryngeal mask (LMA™) and laryngeal tube (LT®) with the perilaryngeal airway (CobraPLA®) in brief paediatric surgical procedures(Australian Soc Anaesthetists, 2008) Kaya, G.; Koyuncu, O.; Turan, N.; Turan, A.We compared the laryngeal mask airway (LMA (TM)) and the laryngeal tube (LT (R)) with the perilaryngeal airway (CobraPLA (R), PLA) in anaesthetised, paralysed children having brief surgical procedures. After obtaining informed consent, 90 paediatric ASA Status 1 and 2 patients awaiting short surgical procedures were randomised to have their airways managed with an LMA, LT or PLA.,Anaesthesia was induced with sevofluarane (2.5 to 4%) and muscle paralysis with mivacurium (0.2 mg/kg intravenously). The number of insertion attempts, time taken to insert the device, haemodynamic responses to insertion (mean arterial blood pressure, heart rate, pulse oximetry and end-tidal CO), clinical performance and occurence of postoperative sore throat were recorded. When the airway device was removed, it was examined for visible blood. Patients and parents were asked about the occurrence of sore throat, dysphonia and dysphagia 24 hours postoperatively. Heart rate, mean arterial blood pressure, pulse oximetry and end tidal CO2 did not differ among the groups. Insertion times for the devices were similar (LMA: 19 +/- 11.seconds, LT: 21 +/- 12.seconds, PLA: 18 +/- 12 seconds), as were the rates of successful insertion at first attempt (LMA 66.7%; LT 70.0%; PLA 73.3%). The number and type of airway interventions to achieve at? affective airway were comparable. When the airways were removed, positive blood traces were noted on 20% of the LMAs, 20% of the PLAs and 10% of the LTs. Haemodynamic, ventilation and oxygenation variables throughout the surgery were similar with LMA, LT and PLA and there were no significant differences in insertion time or signs or symptoms of mucosal trauma when these devices were used in paralysed children.Öğe Does the efficacy of supplemental oxygen for the prevention of postoperative nausea and vomiting depend on the measured outcome, observational period or site of surgery?(Wiley, 2006) Turan, A.; Apfel, C. C.; Kumpch, M.; Danzeisen, O.; Eberhart, L. H. J.; Forst, H.; Heringhaus, C.High intra-operative oxygen concentration reportedly reduces postoperative nausea and vomiting (PONV), but recent data are conflicting. Therefore, we tested whether the effectiveness of supplemental oxygen depends on the endpoint (nausea vs. vomiting), observation interval (early vs. late) or surgical field (abdominal vs. non-abdominal). We randomly assigned 560 adult patients undergoing various elective procedures with a PONV risk. of at least 40% to intra-operative 80% (supplemental) or 30% oxygen (control). Potential confounding factors were similar between groups. Incidences of nausea were similar in the groups during early (12% (supplemental) vs. 10% (control), p = 0.43) and late intervals, 26% vs. 20%, p = 0.09, as were the incidences of vomiting (early: 2% vs. 3%, p = 0.40; late: 8% vs. 9%, p = 0.75). Supplemental oxygen was no more effective at reducing PONV in abdominal (40% vs. 31%, p = 0.37) than in non-abdominal surgery (25% vs. 21%, p = 0.368). Thus, supplemental oxygen was unable to reduce PONY independent of the endpoint, observational period or site of surgery.Öğe Effect of oxygenation and suction in monitored anaesthesia care of eye surgery(Lippincott Williams & Wilkins, 2004) Turan, A.; Esgin, H.; Seker, S.; Pamukcu, Z.[Abstract Not Available]Öğe Gabapentin reduces cardiovascular responses to laryngoscopy and tracheal intubation(Lippincott Williams & Wilkins, 2006) Memis, D.; Turan, A.; Karamanlioglu, B.; Seker, S.; Ture, M.Background and objective: We have compared the effects of gabapentin on arterial pressure and heart rate at induction of anaesthesia and tracheal intubation in a randomized double-blind study. Methods: Ninety normotensive patients (ASA I) undergoing elective surgery were divided into three groups of 30 patients each. Patients received oral placebo (Group I), 400 mg of gabapentin (Group 11) or 800 mg of gabapentin (Group III) 1 h prior to surgery in, the operating theatre. After induction of anaesthesia heart rate and mean arterial pressure were recorded at baseline 1, 3, 5, 10 and 15 min after intubation. Results: Patients receiving placebo and 400 mg gabapentin showed a significant increase in blood pressure and heart rate associated with tracheal intubation compared to baseline levels and Group III. There was significant decrease in heart rate and arterial pressure in Group III after intubation 1, 3, 5 and 10 min (P < 0.001, P < 0.001, P < 0.05 and P < 0.05, respectively) compared to Groups I and II. Conclusion: Given 1 h before operation gabapentin 800 mg blunted the arterial pressure and heart rate increase in first 10min due to endotracheal intubation. Oral administration of gabapentin 800 mg before induction of anaesthesia is a simple and practical method for attenuating pressor response to laryngoscopy and tracheal intubation after standard elective induction.Öğe Patients' willingness to pay for anti-emetic treatment(Wiley, 2007) Kerger, H.; Turan, A.; Kredel, M.; Stuckert, U.; Alsip, N.; Gan, T. J.; Apfel, C. C.Background: Post-operative nausea and vomiting (PONV) is a common complication of anaesthesia. This study was conducted in 100 German and 100 Turkish patients scheduled for elective surgery under general anaesthesia to assess the amount patients were willing to pay for an anti-emetic that completely prevented PONV. Methods: Post-operatively, using Dixon's up and down method, patients completed an interactive computer questionnaire with a random starting point to determine how much of their own money they were willing to pay for a totally effective anti-emetic treatment. Results: On average, participants were willing to pay e65 in Germany and e68 in Turkey to avoid PONV. However, patients who actually experienced PONV were willing to pay larger amounts: e96 in Germany and e99 in Turkey. The amount patients were willing to pay was related to female sex, history of motion sickness, non-smoking status and better education. Conclusions: Despite differences in political and cultural origin, health care system and financial background, the amount patients were willing to pay for an effective anti-emetic was similar in both Germany and Turkey to that reported previously for the USA.Öğe The prevention of pain from injection of propofol by dexmedetomidine and comparison with lidocaine(Lippincott Williams & Wilkins, 2004) Turan, A.; Memis, D.; Kaya, G.; Karamanlyoglu, B.; Pamukcu, Z.[Abstract Not Available]
