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    Investigation of the relationship between osteoarthritis and osteoporosis by osteodensitometer in postmenopausal women
    (1997) Hakguder A.; Unalan H.; Kokino S.; Ozdemir F.
    In the present study, radiographic grades of osteoarthritis were compared with the results of bone mineral density measured by X-ray absorptiometry (DXA) method in 24 postmenopausal women. For all the regions examined, increase in radiographic grades of osteoarthritis showed a parallel rise in bone density which was measured from the lateral part of L3 corpus. These results were especially significant for osteoarthritis of the hand and seemed to be confirmed by the other reports in the literature. Obesity was found to have no influence on osteoarthritis and osteoporosis in this study and this was a conflicting result with the previous reports. The results of our study showed that in the postmenopausal period in which the incidence of osteoporosis is expected to be high, increase in the severity of osteoarthritis coexists with the increase in vertebral bone density and it was suggested that these two conditions are inversely related.
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    Serum antibodies to oral anaerobic bacteria in patients with rheumatoid arthritis
    (Medscape Health Network, 2005) Ogrendik M.; Kokino S.; Ozdemir F.; Bird P.S.; Hamlet S.
    Background: This study was conducted to determine the component that causes the disease in rheumatoid arthritis (RA), which shows great resemblance to periodontitis in a pathologic context. Materials and Methods: Within this study, the pathogen-specific IgG levels formed against Porphyromonas gingivalis FDC 381, Prevotella melaninogenica ATCC 25845, Actinobacillus actinomycetemcomitans Y4, Bacteroides forsythus ATCC 43047, and Prevotella intermedia 25611 oral bacteria were researched from the blood serum samples of 30 RA patients and 20 healthy controls with the enzyme-linked immunosorbent assay (ELISA) method. Results: The IgG levels of P gingivalis, P intermedia, P melaninogenica, and B forsythus were found to be significantly higher in RA patients when compared with those of the controls. Of the other bacteria antibodies, A actinomycetemcomitans was not found at greater levels in RA serum samples in comparison with the healthy samples. Conclusion: The antibodies formed against P gingivalis, P intermedia, P melaninogenica, and B forsythus could be important to the etiopathogenesis of RA. © 2005 Medscape.