Serum antibodies to oral anaerobic bacteria in patients with rheumatoid arthritis
Küçük Resim Yok
Tarih
2005
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Medscape Health Network
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Background: This study was conducted to determine the component that causes the disease in rheumatoid arthritis (RA), which shows great resemblance to periodontitis in a pathologic context. Materials and Methods: Within this study, the pathogen-specific IgG levels formed against Porphyromonas gingivalis FDC 381, Prevotella melaninogenica ATCC 25845, Actinobacillus actinomycetemcomitans Y4, Bacteroides forsythus ATCC 43047, and Prevotella intermedia 25611 oral bacteria were researched from the blood serum samples of 30 RA patients and 20 healthy controls with the enzyme-linked immunosorbent assay (ELISA) method. Results: The IgG levels of P gingivalis, P intermedia, P melaninogenica, and B forsythus were found to be significantly higher in RA patients when compared with those of the controls. Of the other bacteria antibodies, A actinomycetemcomitans was not found at greater levels in RA serum samples in comparison with the healthy samples. Conclusion: The antibodies formed against P gingivalis, P intermedia, P melaninogenica, and B forsythus could be important to the etiopathogenesis of RA. © 2005 Medscape.
Açıklama
Anahtar Kelimeler
Immunoglobulin G Antibody; Actinobacillus Actinomycetemcomitans; Adult; Aged; Anaerobic Bacterium; Antibody Titer; Article; Clinical Article; Controlled Study; Enzyme Linked Immunosorbent Assay; Female; Human; Immunoglobulin Blood Level; Male; Mouth Flora; Nonhuman; Pathogenesis; Periodontitis; Porphyromonas Gingivalis; Prevotella Intermedia; Prevotella Melaninogenica; Rheumatoid Arthritis; Tannerella Forsythensis
Kaynak
MedGenMed Medscape General Medicine
WoS Q Değeri
Scopus Q Değeri
N/A
Cilt
7
Sayı
2
