Tocolysis and corticosteroids: Neonatal results

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dc.authorscopusid6603020540
dc.authorscopusid7003640007
dc.authorscopusid57213763936
dc.authorscopusid6506122868
dc.contributor.authorVarol F.
dc.contributor.authorAcunas B.
dc.contributor.authorCeylan B.
dc.contributor.authorKircuval O.
dc.date.accessioned2024-06-12T10:28:13Z
dc.date.available2024-06-12T10:28:13Z
dc.date.issued1999
dc.description.abstractOBJECTIVE: This study was performed to investigate the beneficial effects of prenatal application of corticosteroids on neonatal morbidity and mortality in the management of preterm labor and preterm premature rupture of membranes. STUDY DESIGN: We performed an analysis of the data related to preterm births between 1995-1998 in which glucocorticoids were used as additional treatment. The study was followed as four groups: Group A: No corticosteroid or tocolytic use, Group B: Corticosteroids alone, Group C: Tocolytic therapy alone, Group D: Both tocolytic and corticosteroid use. Primary outcome included respiratory distress syndrome, intraventricular hemorrhage, necrotizing enterocolitis, neonatal infection and neonatal mortality. A chi-square test was performed to test whether glucocorticoids significantly influenced the neonatal outcomes, p value <0.05 was considered significant. RESULTS: Among the 121 patients with gestational age between 26- 34 weeks, although corticosteroids seemed to have beneficial effects on neonatal outcomes including respiratory distress syndrome, intraventricular hemorrhage, necrotizing enterocolitis, these were not clearcut data on corticosteroids beneficial effects in the managements of preterm births and preterm premature rupture of membranes. The data were shown in Table enclosed. CONCLUSION: More clinical data is needed to evaluate beneficial effects of corticosteroids in the preterm birth and premature rupture of membranes.en_US
dc.identifier.endpage106en_US
dc.identifier.issn1016-5126
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-0032870932en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage102en_US
dc.identifier.urihttps://hdl.handle.net/20.500.14551/17146
dc.identifier.volume13en_US
dc.indekslendigikaynakScopusen_US
dc.language.isotren_US
dc.relation.ispartofJinekoloji ve Obstetrik Dergisien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCorticosteroids; Preterm Delivery; Tocolysisen_US
dc.subjectCorticosteroid; Glucocorticoid; Article; Brain Hemorrhage; Clinical Article; Clinical Trial; Controlled Clinical Trial; Controlled Study; Human; Necrotizing Enterocolitis; Newborn; Newborn Infection; Newborn Morbidity; Newborn Mortality; Premature Fetus Membrane Rupture; Premature Labor; Randomized Controlled Trial; Respiratory Distress Syndrome; Tocolysis; Treatment Outcomeen_US
dc.titleTocolysis and corticosteroids: Neonatal resultsen_US
dc.title.alternativePreterm dogumda neonatal sonuclar: Tokoliz ve kortikosteroid uygulamalarien_US
dc.typeArticleen_US

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