Tocolysis and corticosteroids: Neonatal results
Küçük Resim Yok
Tarih
1999
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
OBJECTIVE: This study was performed to investigate the beneficial effects of prenatal application of corticosteroids on neonatal morbidity and mortality in the management of preterm labor and preterm premature rupture of membranes. STUDY DESIGN: We performed an analysis of the data related to preterm births between 1995-1998 in which glucocorticoids were used as additional treatment. The study was followed as four groups: Group A: No corticosteroid or tocolytic use, Group B: Corticosteroids alone, Group C: Tocolytic therapy alone, Group D: Both tocolytic and corticosteroid use. Primary outcome included respiratory distress syndrome, intraventricular hemorrhage, necrotizing enterocolitis, neonatal infection and neonatal mortality. A chi-square test was performed to test whether glucocorticoids significantly influenced the neonatal outcomes, p value <0.05 was considered significant. RESULTS: Among the 121 patients with gestational age between 26- 34 weeks, although corticosteroids seemed to have beneficial effects on neonatal outcomes including respiratory distress syndrome, intraventricular hemorrhage, necrotizing enterocolitis, these were not clearcut data on corticosteroids beneficial effects in the managements of preterm births and preterm premature rupture of membranes. The data were shown in Table enclosed. CONCLUSION: More clinical data is needed to evaluate beneficial effects of corticosteroids in the preterm birth and premature rupture of membranes.
Açıklama
Anahtar Kelimeler
Corticosteroids; Preterm Delivery; Tocolysis, Corticosteroid; Glucocorticoid; Article; Brain Hemorrhage; Clinical Article; Clinical Trial; Controlled Clinical Trial; Controlled Study; Human; Necrotizing Enterocolitis; Newborn; Newborn Infection; Newborn Morbidity; Newborn Mortality; Premature Fetus Membrane Rupture; Premature Labor; Randomized Controlled Trial; Respiratory Distress Syndrome; Tocolysis; Treatment Outcome
Kaynak
Jinekoloji ve Obstetrik Dergisi
WoS Q Değeri
Scopus Q Değeri
N/A
Cilt
13
Sayı
2
