The Role of Iron in Heart Failure: a Literature Review

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dc.contributor.authorErsoy, Berkin
dc.contributor.authorYamak, Yaren
dc.date.accessioned2021-11-20T10:27:08Z
dc.date.available2021-11-20T10:27:08Z
dc.date.issued2021
dc.departmentTrakya Üniversitesien_US
dc.description.abstractIron has a key role in the energy generation of the cell. Different organs utilize iron for their diverse needs. The heart is an organ that demands high energy. Nearly one-third of stable heart failure patients and half of the hospitalized patients, regardless of their heart failure status, have anemia. The potential cause of anemia in heart failure patients is found to be multifactorial. Iron deficiency anemia is associated with the reduced number of red blood cells, which transport oxygen into the tissues of the human body. Therefore, in iron deficiency, mitochondria produce less energy. Since iron deficiency has a very important role in the prognosis of heart failure, since the beginning of the 2000s, researchers have conducted several studies and trials, investigating the effect of correcting iron deficiency on the clinical and symptomatic outcomes of heart failure. The most recent results of those studies and trials suggest that intravenous iron therapy in heart failure with reduced ejection fraction patients is associated with improved exercise capability, quality of life, and New York Heart Association class. Ongoing trials such as Ferinject Assessment in Patients with Iron Deficiency and Chronic Heart Failure 2 are aimed more into investigating hospitalization and mortality rates of patients on intravenous iron therapy.en_US
dc.identifier.dergipark963029en_US
dc.identifier.endpage63en_US
dc.identifier.issn2148-4724
dc.identifier.issn2548-0030
dc.identifier.issue2en_US
dc.identifier.startpage58en_US
dc.identifier.urihttps://dergipark.org.tr/tr/pub/tmsj/issue/63592/963029
dc.identifier.urihttps://dergipark.org.tr/tr/download/article-file/1861944
dc.identifier.urihttps://hdl.handle.net/20.500.14551/6282
dc.identifier.volume8en_US
dc.language.isoenen_US
dc.publisherTrakya Üniversitesien_US
dc.relation.ispartofTurkish Medical Student Journalen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Başka Kurum Yazarıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectironen_US
dc.subjectanemiaen_US
dc.subjectheart failureen_US
dc.titleThe Role of Iron in Heart Failure: a Literature Reviewen_US
dc.typeArticleen_US

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Turkish Medical Student Journal