A potential marker of bare metal stent restenosis: monocyte count - to- HDL cholesterol ratio

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dc.contributor.authorUcar, Fatih Mehmet
dc.date.accessioned2024-06-12T11:09:27Z
dc.date.available2024-06-12T11:09:27Z
dc.date.issued2016
dc.departmentTrakya Üniversitesien_US
dc.description.abstractBackground: Oxidation and inflammation play significant roles in the pathogenesis of coronary artery diseases. Monocyte count to high-density lipoprotein (HDL) cholesterol ratio (MHR) is a new marker and has revealed as an indicator of inflammation in the literature. The present study aimed to search the effect of MHR on in-stent restenosis (ISR) in patients with stable or unstable angina pectoris undergoing bare-metal stent (BMS) implantation. Methods: A total of 468 consecutive stable or unstable angina pectoris patients (mean age 60.3 +/- 10.1 and 70 % men) who had undergone successful BMS implantation were included the study. Serum samples were obtained before the procedure. Results: The mean period between two coronary angiography procedures was 14 +/- 7.9 months. The baseline MHR levels were significantly higher in patients that had ISR (odds ratio, 3.64; 95 % confidence interval, 2.45-4.84; P < 0. 001). Stent diameter, the time between the two coronary angiographic studies, uric acid and MHR levels emerged as independent predictors of ISR. Conclusions: Our results indicate that elevated MHR is an independent and powerful predictor of ISR in patients with stable or unstable angina pectoris who underwent successful BMS implantation.en_US
dc.identifier.doi10.1186/s12872-016-0367-3
dc.identifier.issn1471-2261
dc.identifier.pmid27716070en_US
dc.identifier.scopus2-s2.0-84989311505en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://doi.org/10.1186/s12872-016-0367-3
dc.identifier.urihttps://hdl.handle.net/20.500.14551/22793
dc.identifier.volume16en_US
dc.identifier.wosWOS:000385774400001en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherBiomed Central Ltden_US
dc.relation.ispartofBmc Cardiovascular Disordersen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectNovel Markeren_US
dc.subjectMonocyte /HDL Cholesterol Ratioen_US
dc.subjectInstent Restenosisen_US
dc.subjectBare Metalen_US
dc.subjectPercutaneous Coronary Interventionen_US
dc.subjectDensity-Lipoproteinen_US
dc.subjectIntimal Hyperplasiaen_US
dc.subjectArtery-Diseaseen_US
dc.subjectHeart-Diseaseen_US
dc.subjectInflammationen_US
dc.subjectAngioplastyen_US
dc.subjectThrombosisen_US
dc.subjectEraen_US
dc.titleA potential marker of bare metal stent restenosis: monocyte count - to- HDL cholesterol ratioen_US
dc.typeArticleen_US

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