A potential marker of bare metal stent restenosis: monocyte count - to- HDL cholesterol ratio
Küçük Resim Yok
Tarih
2016
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Biomed Central Ltd
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Background: Oxidation and inflammation play significant roles in the pathogenesis of coronary artery diseases. Monocyte count to high-density lipoprotein (HDL) cholesterol ratio (MHR) is a new marker and has revealed as an indicator of inflammation in the literature. The present study aimed to search the effect of MHR on in-stent restenosis (ISR) in patients with stable or unstable angina pectoris undergoing bare-metal stent (BMS) implantation. Methods: A total of 468 consecutive stable or unstable angina pectoris patients (mean age 60.3 +/- 10.1 and 70 % men) who had undergone successful BMS implantation were included the study. Serum samples were obtained before the procedure. Results: The mean period between two coronary angiography procedures was 14 +/- 7.9 months. The baseline MHR levels were significantly higher in patients that had ISR (odds ratio, 3.64; 95 % confidence interval, 2.45-4.84; P < 0. 001). Stent diameter, the time between the two coronary angiographic studies, uric acid and MHR levels emerged as independent predictors of ISR. Conclusions: Our results indicate that elevated MHR is an independent and powerful predictor of ISR in patients with stable or unstable angina pectoris who underwent successful BMS implantation.
Açıklama
Anahtar Kelimeler
Novel Marker, Monocyte /HDL Cholesterol Ratio, Instent Restenosis, Bare Metal, Percutaneous Coronary Intervention, Density-Lipoprotein, Intimal Hyperplasia, Artery-Disease, Heart-Disease, Inflammation, Angioplasty, Thrombosis, Era
Kaynak
Bmc Cardiovascular Disorders
WoS Q Değeri
Q3
Scopus Q Değeri
Q2
Cilt
16
