Preoperative thrombocytosis is an independent prognostic factor in stage III and IV endometrial cancer

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dc.contributor.authorScholz, HS
dc.contributor.authorPetru, E
dc.contributor.authorGücer, F
dc.contributor.authorHaas, J
dc.contributor.authorTamussino, K
dc.contributor.authorWinter, R
dc.date.accessioned2024-06-12T11:16:19Z
dc.date.available2024-06-12T11:16:19Z
dc.date.issued2000
dc.departmentTrakya Üniversitesien_US
dc.description.abstractBackground: To identify prognostic factors in stage III and IV endometrial cancer with special attention to pretreatment platelet count. Materials and Methods: 59 patients with FIGO stage III or IV disease operated on between 1983 and 1993 were analyzed. Patients with preoperative thrombocytosis were compared with those without thrombocytosis. Prognostic factors were analyzed with a Cox proportional hazard model. Results: With the exception of age, there were no significant differences between patients with or without thrombocytosis. At multivariate analysis, five-year disease-free survival was influenced significantly by FIGO stage (stage III vs stage IV; p=0.009), thrombocytosis (p=0.02) and cervical involvement (p=0.024). Similarly, overall five-year survival was significantly influenced by stage (p<0.001), cervical involvement (p=0.005) and thrombocytosis (p=0.01). Age, histology, grade, myometrial invasion, lymph-vascular space involvement or spread to adnexae were not significantly associated with survival. Conclusion: Thrombocytosis is an independent prognostic factor in stage III and IV endometrial cancer.en_US
dc.identifier.endpage3985en_US
dc.identifier.issn0250-7005
dc.identifier.issue5Cen_US
dc.identifier.pmid11268488en_US
dc.identifier.startpage3983en_US
dc.identifier.urihttps://hdl.handle.net/20.500.14551/24281
dc.identifier.volume20en_US
dc.identifier.wosWOS:000165634200059en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherInt Inst Anticancer Researchen_US
dc.relation.ispartofAnticancer Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectThrombocytosisen_US
dc.subjectEndometrial Canceren_US
dc.subjectPrognosisen_US
dc.subjectEpithelial Ovarian-Canceren_US
dc.subjectCervical-Canceren_US
dc.subjectTumor Progressionen_US
dc.subjectPlatelet Counten_US
dc.subjectCarcinomaen_US
dc.subjectThrombospondin-1en_US
dc.subjectSurvivalen_US
dc.subjectWomenen_US
dc.titlePreoperative thrombocytosis is an independent prognostic factor in stage III and IV endometrial canceren_US
dc.typeArticleen_US

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