Clinicopathological Features of Myeloid Sarcoma Patients From a Single Center Experience

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dc.contributor.authorAkay, Fatih Erkan
dc.contributor.authorKırkızlar, Hakkı Onur
dc.contributor.authorMercan, Elif
dc.contributor.authorÖz Puyan, Fulya
dc.date.accessioned2021-11-20T10:26:27Z
dc.date.available2021-11-20T10:26:27Z
dc.date.issued2020
dc.departmentFakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, İç Hastalıkları Anabilim Dalıen_US
dc.departmentFakülteler, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Tıbbi Patoloji Anabilim Dalıen_US
dc.description.abstractAims: This retrospective study aims to emphasize clinicopathological data and diagnosis of an uncommon myeloid neoplasm;myeloid sarcoma. Methods: Data of all patients from 2000-2019 were retrieved from the archives of Trakya University Schoolof Medicine Hematology and Pathology Departments. Patients’ charts were examined retrospectively by collecting data including age, gender, anatomic site, history of hematological malignancy, blood count, pathological characteristics and treatmentsadministered. Results: There were 8 patients; 6 male and 2 female. The median age was 42.5 years (range: 29-69 years). Themost prevalently involved sites were skin, lymph node and bone/soft tissue. There were six patients as myeloid sarcoma withpreexisting or concurrent acute myeloid leukemia, one patient as de novo and one patient as acute myeloid leukemia with myelodysplasia related changes. One of the concurrent acute myeloid leukemia patients was Down syndrome related acute myeloidleukemia with myeloid sarcoma. Immunohistochemically, out of 8 patients, 4 were of myelomonocytic, 2 were of the myelocyticand 2 were of the monocytic differentiation. Conclusion: Myeloid sarcoma is a tumor mass made up of immature myeloid blastsappearing at an anatomical site other than bone marrow. Taking into account of having a challenging diagnosis, unusual cellularinfiltration at any site on a patient especially with a history of acute myeloid leukemia should have myeloid sarcoma in theirdifferential diagnosis. Keywords: Myeloid sarcoma, acute myeloid leukemia, myeloid neoplasiaen_US
dc.identifier.dergipark700195en_US
dc.identifier.endpage33en_US
dc.identifier.issn2148-4724
dc.identifier.issn2548-0030
dc.identifier.issue1en_US
dc.identifier.startpage26en_US
dc.identifier.urihttps://dergipark.org.tr/tr/pub/tmsj/issue/52947/700195
dc.identifier.urihttps://dergipark.org.tr/tr/download/article-file/997002
dc.identifier.urihttps://hdl.handle.net/20.500.14551/6054
dc.identifier.volume7en_US
dc.language.isoenen_US
dc.publisherTrakya Üniversitesien_US
dc.relation.ispartofTurkish Medical Student Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectMyeloid sarcomaen_US
dc.subjectacute myeloid leukemiaen_US
dc.subjectmyeloid neoplasiaen_US
dc.titleClinicopathological Features of Myeloid Sarcoma Patients From a Single Center Experienceen_US
dc.typeArticleen_US

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