Polyvinyl alcohol-trypsin as a catalyst for amino acid ester synthesis in organic media

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dc.authoridKilic, ismail/0000-0002-3270-063X
dc.authorwosidKilic, ismail/I-5823-2019
dc.contributor.authorYesiloglu, Y
dc.contributor.authorKilic, I
dc.date.accessioned2024-06-12T11:00:28Z
dc.date.available2024-06-12T11:00:28Z
dc.date.issued2004
dc.departmentTrakya Üniversitesien_US
dc.description.abstractThe bovine trypsin-catalyzed synthesis of N-alpha-benzoyi-DL-arginine esters from N-benzoyl-DL-arginine were studied in various organic solvents. Trypsin was immobilized to polyvinyl alcohol (PVA) by adsorption from its aqueous solutions. Immobilized enzyme showed higher catalytic activities than free enzyme for amino acid esterification in ethanol. The yield of ester is strongly dependent upon the PVA/trypsin ratio and water content in the reaction medium. The rate and equilibrium constant of the ester formation reaction are also dependent on water content.en_US
dc.identifier.doi10.1081/PB-200031028
dc.identifier.endpage375en_US
dc.identifier.issn1082-6068
dc.identifier.issue4en_US
dc.identifier.pmid15553905en_US
dc.identifier.scopus2-s2.0-7244248724en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage365en_US
dc.identifier.urihttps://doi.org/10.1081/PB-200031028
dc.identifier.urihttps://hdl.handle.net/20.500.14551/20849
dc.identifier.volume34en_US
dc.identifier.wosWOS:000224778200005en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherMarcel Dekker Incen_US
dc.relation.ispartofPreparative Biochemistry & Biotechnologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectEnzymatic Reactionen_US
dc.subjectEster Synthesisen_US
dc.subjectBovine Trypsinen_US
dc.subjectOrganic Solventen_US
dc.subjectWater Activityen_US
dc.subjectPeptide-Synthesisen_US
dc.subjectDipeptide Synthesisen_US
dc.subjectStabilized Trypsinen_US
dc.subjectWater Activityen_US
dc.subjectLipaseen_US
dc.subjectProteaseen_US
dc.titlePolyvinyl alcohol-trypsin as a catalyst for amino acid ester synthesis in organic mediaen_US
dc.typeArticleen_US

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