Effect of two different heparin neutralization methods on postoperative drainage in open heart surgery

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dc.authorscopusid7004591561
dc.authorscopusid8675977500
dc.authorscopusid6602393555
dc.authorscopusid6506832953
dc.authorscopusid7005322966
dc.contributor.authorEge T.
dc.contributor.authorÇikirikçio?lu M.
dc.contributor.authorArar C.
dc.contributor.authorAcipayam M.
dc.contributor.authorDuran E.
dc.date.accessioned2024-06-12T10:28:56Z
dc.date.available2024-06-12T10:28:56Z
dc.date.issued2002
dc.description.abstractIntroduction and Aim: To define the changes in activated coagulation time (ACT) and postoperative drainage volume with two different heparin neutralization methods in patients who had coronary bypass surgery. Material and Methods: 53 patients who had coronary bypass surgery between January 1, 2002 and July 31,2002 at Trakya University Faculty of Medicine Department of Cardiovascular Surgery were taken into the study. Patients were separated into two groups randomly. The patients that were applied protamine, 1.3 folds of total heparin during the operation were as group 1 (n=29) and the patients that heparin neutralization was applied by the calculation of protamine dosage with a graphic at the end of cardiopulmonary bypass (CPB) were as group 2 (n=24). Postoperative ACT and drainage volumes of the groups were compared. Findings: Among groups there was no significent difference in terms of age, sex, body mass index, number of grafts, CPB time, cross clamp time, EF and use of LIMA. There was no significent difference in ACT values 5 minutes after protamine application (Group 1= 129.8± 12.6 sec, Group 2= 128.5± 14.1 sec). In group 1, ACT values at 2, 4 and 6 hours after protamine application (131.9± 19.2, 129.129.2± 11.5 and 127.0± 9.2 sec) were prominently higher than in group 2 (118.5± 13.5, 114.4± 9.6 and 111.9± 10.9 sec).en_US
dc.identifier.endpage404en_US
dc.identifier.issn1302-0471
dc.identifier.issue4en_US
dc.identifier.scopus2-s2.0-0036985952en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage399en_US
dc.identifier.urihttps://hdl.handle.net/20.500.14551/17480
dc.identifier.volume44en_US
dc.indekslendigikaynakScopusen_US
dc.language.isotren_US
dc.publisherGulhane Askeri Tip Akademisien_US
dc.relation.ispartofGulhane Medical Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectHeparin; Protamine; Adult; Age; Aged; Aorta Clamping; Article; Bleeding; Blood Clotting Time; Body Mass; Cardiopulmonary Bypass; Controlled Study; Coronary Artery Bypass Graft; Dose Calculation; Female; Heart Tamponade; Heparinization; Human; Major Clinical Study; Male; Open Heart Surgery; Postoperative Care; Sex Differenceen_US
dc.titleEffect of two different heparin neutralization methods on postoperative drainage in open heart surgeryen_US
dc.title.alternativeAçik kalp cerrahisi?nde farkli i?ki? hepari?n nötrali?zasyon yöntemi?ni?n postoperati?f drenaja etki?si?en_US
dc.typeArticleen_US

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