Effect of two different heparin neutralization methods on postoperative drainage in open heart surgery
Küçük Resim Yok
Tarih
2002
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Gulhane Askeri Tip Akademisi
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Introduction and Aim: To define the changes in activated coagulation time (ACT) and postoperative drainage volume with two different heparin neutralization methods in patients who had coronary bypass surgery. Material and Methods: 53 patients who had coronary bypass surgery between January 1, 2002 and July 31,2002 at Trakya University Faculty of Medicine Department of Cardiovascular Surgery were taken into the study. Patients were separated into two groups randomly. The patients that were applied protamine, 1.3 folds of total heparin during the operation were as group 1 (n=29) and the patients that heparin neutralization was applied by the calculation of protamine dosage with a graphic at the end of cardiopulmonary bypass (CPB) were as group 2 (n=24). Postoperative ACT and drainage volumes of the groups were compared. Findings: Among groups there was no significent difference in terms of age, sex, body mass index, number of grafts, CPB time, cross clamp time, EF and use of LIMA. There was no significent difference in ACT values 5 minutes after protamine application (Group 1= 129.8± 12.6 sec, Group 2= 128.5± 14.1 sec). In group 1, ACT values at 2, 4 and 6 hours after protamine application (131.9± 19.2, 129.129.2± 11.5 and 127.0± 9.2 sec) were prominently higher than in group 2 (118.5± 13.5, 114.4± 9.6 and 111.9± 10.9 sec).
Açıklama
Anahtar Kelimeler
Heparin; Protamine; Adult; Age; Aged; Aorta Clamping; Article; Bleeding; Blood Clotting Time; Body Mass; Cardiopulmonary Bypass; Controlled Study; Coronary Artery Bypass Graft; Dose Calculation; Female; Heart Tamponade; Heparinization; Human; Major Clinical Study; Male; Open Heart Surgery; Postoperative Care; Sex Difference
Kaynak
Gulhane Medical Journal
WoS Q Değeri
Scopus Q Değeri
Q4
Cilt
44
Sayı
4
