The Influence of Intercurrent Diseases on the Course of Hiv in Association With Active Tuberculosis

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dc.contributor.authorKolotylo, Tetiana
dc.contributor.authorPetrochenkov, Hennadii
dc.contributor.authorGritsiuk, Orest
dc.date.accessioned2021-11-20T10:27:20Z
dc.date.available2021-11-20T10:27:20Z
dc.date.issued2019
dc.departmentTrakya Üniversitesien_US
dc.description.abstractAims: We aimed to establish the features of the course of HIV in association with active tuberculosis in the presence of other secondary diseases and opportunistic infections. Methods: In this research, 155 HIV patients with active newly diagnosed tuberculosis and 76 diagnosed only with tuberculosis have been comprehensively immunologically examined. The HIV/Tuberculosis group was divided into 3 subgroups depending on the time of adherence of Tuberculosis to HIV infection. STATISTICA 6.0 was used for data analysis, and when the number of observations is less than 20, the Wilcoxon nonparametric method for independent populations or the dispersive analysis of Kruskal-Wallis was used. In addition, Mann-Whitney U test was used to compare two independent groups. Results: The number of CD4 + T-lymphocytes was lower compared with patients without secondary ailments. However, the level of serum concentration and spontaneous production of IL-4 and IFN-?, as well as VL HIV was higher in the presence of other secondary diseases. Conclusion: In the presence of secondary diseases and opportunistic infections, the number of CD4 + T-lymphocytes was lower, and the level of serum concentration and spontaneous production of IL-4, IFN-? and viral load was higher compared to patients without these ailments. In the case of secondary diseases and opportunistic infections, the frequency of death of patients was significantly higher than in their absenceen_US
dc.identifier.dergipark541684en_US
dc.identifier.issn2148-4724
dc.identifier.issn2548-0030
dc.identifier.issue1en_US
dc.identifier.urihttps://dergipark.org.tr/tr/pub/tmsj/issue/43969/541684
dc.identifier.urihttps://dergipark.org.tr/tr/download/article-file/674001
dc.identifier.urihttps://hdl.handle.net/20.500.14551/6336
dc.identifier.volume6en_US
dc.language.isoenen_US
dc.publisherTrakya Üniversitesien_US
dc.relation.ispartofTurkish Medical Student Journalen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Başka Kurum Yazarıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectHIVen_US
dc.subjecttuberculosisen_US
dc.subjectviral loaden_US
dc.subjectmortalityen_US
dc.subjectcytokinesen_US
dc.titleThe Influence of Intercurrent Diseases on the Course of Hiv in Association With Active Tuberculosisen_US
dc.typeArticleen_US

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Turkish Medical Student Journal