Effects of mannitol and dopamine on renal function in coronary artery bypass surgery

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dc.authorscopusid56126302200
dc.authorscopusid14032022300
dc.authorscopusid6504312385
dc.authorscopusid45661857800
dc.authorscopusid55950481100
dc.authorscopusid6505802281
dc.contributor.authorNarin E.B.
dc.contributor.authorÖztekin I.
dc.contributor.authorÖztekin S.D.
dc.contributor.authorTop?cu G.
dc.contributor.authorÖ?ütmen B.
dc.contributor.authorCanik S.
dc.date.accessioned2024-06-12T10:26:28Z
dc.date.available2024-06-12T10:26:28Z
dc.date.issued2014
dc.description.abstractObjective: To compare the effects of dopamine and mannitol which are used to reduce the negative effects of long-term cardio-pulmonary bypass (CPB) on kidney function in according to manner of administration and by the time. Material and Methods: Group 1 (n = 25 patients): Mannitol (M) 1 g kg -1 was added to a priming solution of CPB. Group 2 (n = 25 patients): Dopamine infusion (D) (2 mg kg-1 min-1 IV) was used from induction of anesthesia until end of the operation. Group 3 (n = 25 patients): D (2 mg kg-1 min-1 IV) was used from induction of anesthesia until end of the operation and M 1 g kg-1 in the priming solution of CPB. Group 4 (n = 25 patients) (Control Group): Furosemide was performed in case of a decrease of urine. The values of serum urea, creatinine, albumin, urine microalbumin, urine creatinine, serum cystatin-C were compared to preop and postop periods. Results: Postop Cystatin C levels in Group I, II, III were observed a significant rise. The levels of Microalbumin / creatinine ratio in urine in all the groups at postop were seen advanced statistical significant (p <0.01). Conclusion: To determine kidney damage we have observed that microalbumin / creatinine ratio in urine compared to the Cystatin C level is to be a more sensitive parameter. We think that the use of D (2 ?g kg -1 min-1) combined with M (1 g kg-1) added during CPB is more effective in terms of preventing adverse effects of CPB on renal function.en_US
dc.identifier.doi10.5222/GKDAD.2014.033
dc.identifier.endpage40en_US
dc.identifier.issn1305-5550
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-84899065138en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage33en_US
dc.identifier.urihttps://doi.org/10.5222/GKDAD.2014.033
dc.identifier.urihttps://hdl.handle.net/20.500.14551/16863
dc.identifier.volume20en_US
dc.indekslendigikaynakScopusen_US
dc.language.isotren_US
dc.publisherTurkish Anaesthesiology and Intensive Care Societyen_US
dc.relation.ispartofGogus-Kalp-Damar Anestezi ve Yogun Bakim Dernegi Dergisien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCoronary Surgery; Cystatin-C; Dopamine; Mannitol; Microalbuminen_US
dc.subjectAlbumin; Creatinine; Cystatin C; Dopamine; Furosemide; Mannitol; Urea; Albumin Blood Level; Anesthesia Induction; Article; Comparative Study; Controlled Study; Coronary Artery Bypass Surgery; Creatinine Blood Level; Human; Kidney Function; Major Clinical Study; Urea Blood Level; Urine Levelen_US
dc.titleEffects of mannitol and dopamine on renal function in coronary artery bypass surgeryen_US
dc.title.alternativeMannitol ve dopaminin koroner arter baypas cerrahisinde renal fonksiyonlara etkilerien_US
dc.typeArticleen_US

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