Vascular Changes and Hypoxia in Periodontal Disease as a Link to Systemic Complications

Basit Öğe Kaydı
dc.authorwosidKANTARCI, Alpdogan/KLC-3979-2024
dc.contributor.authorCelik, Dilek
dc.contributor.authorKantarci, Alpdogan
dc.date.accessioned2024-06-12T11:12:18Z
dc.date.available2024-06-12T11:12:18Z
dc.date.issued2021
dc.departmentTrakya Üniversitesien_US
dc.description.abstractThe hypoxic microenvironment caused by oral pathogens is the most important cause of the disruption of dynamic hemostasis between the oral microbiome and the immune system. Periodontal infection exacerbates the inflammatory response with increased hypoxia and causes vascular changes. The chronicity of inflammation becomes systemic as a link between oral and systemic diseases. The vascular network plays a central role in controlling infection and regulating the immune response. In this review, we focus on the local and systemic vascular network change mechanisms of periodontal inflammation and the pathological processes of inflammatory diseases. Understanding how the vascular network influences the pathology of periodontal diseases and the systemic complication associated with this pathology is essential for the discovery of both local and systemic proactive control mechanisms.en_US
dc.description.sponsorshipNIH/NIA [R01AG062496]en_US
dc.description.sponsorshipFundingThis research was funded by a grant from the NIH/NIA R01AG062496.en_US
dc.identifier.doi10.3390/pathogens10101280
dc.identifier.issn2076-0817
dc.identifier.issue10en_US
dc.identifier.pmid34684229en_US
dc.identifier.scopus2-s2.0-85117202838en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://doi.org/10.3390/pathogens10101280
dc.identifier.urihttps://hdl.handle.net/20.500.14551/23103
dc.identifier.volume10en_US
dc.identifier.wosWOS:000711197700001en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherMdpien_US
dc.relation.ispartofPathogensen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectPeriodontal Diseaseen_US
dc.subjectInflammationen_US
dc.subjectHypoxiaen_US
dc.subjectVascular Changesen_US
dc.subjectEndothelial Growth-Factoren_US
dc.subjectInflammatory-Bowel-Diseaseen_US
dc.subjectTumor-Necrosis-Factoren_US
dc.subjectC-Reactive Proteinen_US
dc.subjectPorphyromonas-Gingivalisen_US
dc.subjectHif-1 Activationen_US
dc.subjectAggressive Periodontitisen_US
dc.subjectAtherosclerotic Plaqueen_US
dc.subjectDependent Activationen_US
dc.subjectFactor Vegfen_US
dc.titleVascular Changes and Hypoxia in Periodontal Disease as a Link to Systemic Complicationsen_US
dc.typeReview Articleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu