Vascular Changes and Hypoxia in Periodontal Disease as a Link to Systemic Complications
Küçük Resim Yok
Tarih
2021
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Mdpi
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
The hypoxic microenvironment caused by oral pathogens is the most important cause of the disruption of dynamic hemostasis between the oral microbiome and the immune system. Periodontal infection exacerbates the inflammatory response with increased hypoxia and causes vascular changes. The chronicity of inflammation becomes systemic as a link between oral and systemic diseases. The vascular network plays a central role in controlling infection and regulating the immune response. In this review, we focus on the local and systemic vascular network change mechanisms of periodontal inflammation and the pathological processes of inflammatory diseases. Understanding how the vascular network influences the pathology of periodontal diseases and the systemic complication associated with this pathology is essential for the discovery of both local and systemic proactive control mechanisms.
Açıklama
Anahtar Kelimeler
Periodontal Disease, Inflammation, Hypoxia, Vascular Changes, Endothelial Growth-Factor, Inflammatory-Bowel-Disease, Tumor-Necrosis-Factor, C-Reactive Protein, Porphyromonas-Gingivalis, Hif-1 Activation, Aggressive Periodontitis, Atherosclerotic Plaque, Dependent Activation, Factor Vegf
Kaynak
Pathogens
WoS Q Değeri
Q2
Scopus Q Değeri
Q2
Cilt
10
Sayı
10
