Allergic Rhinitis: Current and Future Treatment Options

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dc.contributor.authorKarganova, Kristina
dc.date.accessioned2021-11-20T10:27:17Z
dc.date.available2021-11-20T10:27:17Z
dc.date.issued2016
dc.departmentTrakya Üniversitesien_US
dc.description.abstractAllergic rhinitis is an inflammation of nasal mucosa occurring in previously sensitized people after exposure to an offending allergen due to specific IgE antibody production. The main symptoms involve nasal obstruction, rhinorrhea, sneezing and itching. Moreover, allergic rhinitis has a significant impact on a person’s quality of life, affecting physical, emotional and social well-being. The pathophysiology of allergic rhinitis is complicated and involves numerous changes within the immune system, including activation and differentiation of various immune cells, degranulation of basophils and mast cells, production of IgE antibodies, cytokines and chemokines, immune cell migration into the site of allergic inflammation. Various treatment options, such as topical glucocorticoids, oral or topical antihistamines, oral leukotriene receptor antagonists, mast cell membrane stabilizers, decongestants, as well as allergen specific immunotherapy and monoclonal anti-IgE antibody are currently available and even more methods are under investigation. The purpose of this article is to review epidemiology, clinical significance, pathophysiology and current and future treatment options for the allergic rhinitis.en_US
dc.identifier.dergipark379048en_US
dc.identifier.endpage65en_US
dc.identifier.issn2148-4724
dc.identifier.issn2548-0030
dc.identifier.issue2en_US
dc.identifier.startpage57en_US
dc.identifier.urihttps://dergipark.org.tr/tr/pub/tmsj/issue/34302/379048
dc.identifier.urihttps://dergipark.org.tr/tr/download/article-file/404674
dc.identifier.urihttps://hdl.handle.net/20.500.14551/6323
dc.identifier.volume3en_US
dc.language.isoenen_US
dc.publisherTrakya Üniversitesien_US
dc.relation.ispartofTurkish Medical Student Journalen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Başka Kurum Yazarıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAllergic rhinitisen_US
dc.subjectimmunologic desensitizationen_US
dc.subjecttreatmenten_US
dc.titleAllergic Rhinitis: Current and Future Treatment Optionsen_US
dc.typeArticleen_US

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Turkish Medical Student Journal