Monitoring of renal function using 99mTc-DMSA and 99mTc-DTPA scintigraphy in patients with spinal cord injury

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dc.authoridCermik, Tevfik Fikret/0000-0001-7622-7277
dc.authoridTuna, Filiz/0000-0002-9563-8028
dc.authoridtuna, hakan/0000-0002-5980-8413
dc.authorwosidCermik, Tevfik Fikret/A-9694-2018
dc.authorwosidTuna, Floriana/K-5198-2016
dc.contributor.authorTuna, H.
dc.contributor.authorCermik, T. F.
dc.contributor.authorTuna, F.
dc.date.accessioned2024-06-12T11:15:30Z
dc.date.available2024-06-12T11:15:30Z
dc.date.issued2012
dc.departmentTrakya Üniversitesien_US
dc.description.abstractAim: The aim of this study was to assess the degree of alterations of renal function by using 99m-technetium dimercaptosuccinic acid (Tc-99m-DMSA) and 99m-technetium diethylenetriaminepentaacetic acid (Tc-99m-DTPA) scintigraphy in spinal cord injury (SCI) patients. Material and methods: Twenty-two consecutive SCI (15 paraplegic and 7 tetraplegic) patients (mean age: 49.1 +/- 13.4 years) who had no urinary symptoms participated in this prospective study. The mean duration of injury was 45.6 +/- 48.8 months before. Sixteen patients had at least one urinary tract infection history. Renal cortical scintigraphy with Tc-99m-DMSA, radionuclide renography with Tc-99m-DTPA and renal ultrasound were performed within 2-week period. Results: Four (18%) patients had serious pathology on their kidneys such as unilateral or bilateral parenchymal scarring and increased background uptake in their renal cortical scintigraphy with Tc-99m-DMSA. Two of them had grade 3-4 pelvicaliceal ectasia on ultrasound. Additionally, 2 of 18 remaining patients had grade 2 pelvicaliceal ectasia on ultrasound. Sixteen (73%) patients had markedly delayed or delayed and decreased functions of one or both of kidneys on radionuclide renography. However, only four patients had grade 2-4 pelvicaliceal ectasia and none of them had a finding of loosening of renal parenchyma. Conclusion: Combined use of renal cortical scintigraphy and radionuclide renography appears to be contributive to renal ultrasound in the long-term follow-up of patients with SCI. Patients with abnormal findings should be closely followed, and early therapeutic interventions may enable lower morbidity and mortality rates in these patients. (C) 2011 Elsevier Espana, S.L. and SEMNIM. All rights reserved.en_US
dc.identifier.doi10.1016/j.remn.2011.12.003
dc.identifier.endpage327en_US
dc.identifier.issn2253-654X
dc.identifier.issue6en_US
dc.identifier.pmid23084015en_US
dc.identifier.startpage322en_US
dc.identifier.urihttps://doi.org/10.1016/j.remn.2011.12.003
dc.identifier.urihttps://hdl.handle.net/20.500.14551/23964
dc.identifier.volume31en_US
dc.identifier.wosWOS:000310477800004en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevier Doyma Slen_US
dc.relation.ispartofRevista Espanola De Medicina Nuclear E Imagen Molecularen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectSpinal Cord Injuryen_US
dc.subjectKidneyen_US
dc.subjectScintigraphyen_US
dc.subjectTc-99m-DMSAen_US
dc.subjectTc-99m-DTPAen_US
dc.subjectTerm Follow-Upen_US
dc.subjectUrinary-Tracten_US
dc.subjectAbdominal Ultrasonographyen_US
dc.subjectRadioisotope Renographyen_US
dc.subjectVesicoureteral Refluxen_US
dc.subjectAcute Pyelonephritisen_US
dc.subjectExcretory Urographyen_US
dc.subjectUltrasounden_US
dc.subjectReproducibilityen_US
dc.subjectSonographyen_US
dc.titleMonitoring of renal function using 99mTc-DMSA and 99mTc-DTPA scintigraphy in patients with spinal cord injuryen_US
dc.typeArticleen_US

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