Monitoring of renal function using 99mTc-DMSA and 99mTc-DTPA scintigraphy in patients with spinal cord injury
Küçük Resim Yok
Tarih
2012
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Elsevier Doyma Sl
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Aim: The aim of this study was to assess the degree of alterations of renal function by using 99m-technetium dimercaptosuccinic acid (Tc-99m-DMSA) and 99m-technetium diethylenetriaminepentaacetic acid (Tc-99m-DTPA) scintigraphy in spinal cord injury (SCI) patients. Material and methods: Twenty-two consecutive SCI (15 paraplegic and 7 tetraplegic) patients (mean age: 49.1 +/- 13.4 years) who had no urinary symptoms participated in this prospective study. The mean duration of injury was 45.6 +/- 48.8 months before. Sixteen patients had at least one urinary tract infection history. Renal cortical scintigraphy with Tc-99m-DMSA, radionuclide renography with Tc-99m-DTPA and renal ultrasound were performed within 2-week period. Results: Four (18%) patients had serious pathology on their kidneys such as unilateral or bilateral parenchymal scarring and increased background uptake in their renal cortical scintigraphy with Tc-99m-DMSA. Two of them had grade 3-4 pelvicaliceal ectasia on ultrasound. Additionally, 2 of 18 remaining patients had grade 2 pelvicaliceal ectasia on ultrasound. Sixteen (73%) patients had markedly delayed or delayed and decreased functions of one or both of kidneys on radionuclide renography. However, only four patients had grade 2-4 pelvicaliceal ectasia and none of them had a finding of loosening of renal parenchyma. Conclusion: Combined use of renal cortical scintigraphy and radionuclide renography appears to be contributive to renal ultrasound in the long-term follow-up of patients with SCI. Patients with abnormal findings should be closely followed, and early therapeutic interventions may enable lower morbidity and mortality rates in these patients. (C) 2011 Elsevier Espana, S.L. and SEMNIM. All rights reserved.
Açıklama
Anahtar Kelimeler
Spinal Cord Injury, Kidney, Scintigraphy, Tc-99m-DMSA, Tc-99m-DTPA, Term Follow-Up, Urinary-Tract, Abdominal Ultrasonography, Radioisotope Renography, Vesicoureteral Reflux, Acute Pyelonephritis, Excretory Urography, Ultrasound, Reproducibility, Sonography
Kaynak
Revista Espanola De Medicina Nuclear E Imagen Molecular
WoS Q Değeri
Q4
Scopus Q Değeri
Cilt
31
Sayı
6
