A comparative study of the effect of icodextrin based peritoneal dialysis and hemodialysis on lipid metabolism

dc.authorscopusid6506443071
dc.authorscopusid6507959144
dc.authorscopusid14035837500
dc.authorscopusid23092622700
dc.authorscopusid55063065800
dc.authorscopusid7403697089
dc.authorscopusid58642492700
dc.contributor.authorKadiroglu A.K.
dc.contributor.authorÜstündag S.
dc.contributor.authorKayabasi H.
dc.contributor.authorYilmaz Z.
dc.contributor.authorYildirim Y.
dc.contributor.authorSen S.
dc.contributor.authorYilmaz M.E.
dc.date.accessioned2024-06-12T10:26:21Z
dc.date.available2024-06-12T10:26:21Z
dc.date.issued2013
dc.description.abstractDyslipidemia is frequent in patients with end stage renal disease. Excessive peritoneal glucose absorption from high glucose-containing peritoneal dialysis solutions may enhance disturbances on the lipid metabolism of patients on peritoneal dialysis. We compared the effect of icodextrin-based peritoneal dialysis therapy with hemodialysis (HD) therapy on lipid metabolism. A total of 157 non-diabetic patients on dialysis at least for 3 months; 78 patients on Icodextrin-based continuous ambulatory peritoneal dialysis (CAPD) (44 M, 34 F) and 79 patients in HD group (47M, 32F) were included into the study. After 12 h of fasting and before the dialysis session, serum urea, creatinin, glucose, Sodium, potasium, and albumin, total cholesterol (TC), triglycerides (TG), very low density lipoprotein (VLDL), low density lipoprotein (LDL)-C, high-density lipoprotein (HDL)-C, apolipoprotein A (Apo A), apolipoprotein B, and lipoprotein a were measured. TG ( P = 0018) and VLDL ( P = 0.022) were lower in CAPD group than HD group, HDL-C ( P < 0.001) and Apo A ( P = 0.001) were higher in CAPD group than in HD group. A total of 24.4% in CAPD group and 11.4% in HD group ( P < 0.034) had normal serum levels of TG, LDL-C, and HDL-C. More patients in CAPD group (47.4%) had high serum Apo A levels than in HD group (21.5%) ( P = 0.001). We suggest that patients receiving icodextrin-based CAPD may have better TG, HDL-C, and Apo A levels than patients on HD.en_US
dc.identifier.doi10.4103/0971-4065.116324
dc.identifier.endpage361en_US
dc.identifier.issn0971-4065
dc.identifier.issue5en_US
dc.identifier.scopus2-s2.0-84883628185en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage358en_US
dc.identifier.urihttps://doi.org/10.4103/0971-4065.116324
dc.identifier.urihttps://hdl.handle.net/20.500.14551/16793
dc.identifier.volume23en_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.relation.ispartofIndian Journal of Nephrologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectContinuous Ambulatory Peritoneal Dialysis; Dislipidemia; Hemodialysis; Icodextrin; Lipoprotein Abnormalitiesen_US
dc.subjectAlbumin; Apolipoprotein A; Apolipoprotein B; Cholesterol; Creatinine; Glucose; High Density Lipoprotein Cholesterol; Icodextrin; Low Density Lipoprotein Cholesterol; Potassium; Sodium; Triacylglycerol; Urea; Very Low Density Lipoprotein; Adult; Aged; Albumin Blood Level; Article; Cholesterol Blood Level; Comparative Study; Continuous Ambulatory Peritoneal Dialysis; Controlled Study; Creatinine Blood Level; Dyslipidemia; Female; Glucose Blood Level; Hemodialysis; Hemodialysis Patient; Human; Lipid Metabolism; Lipoprotein Blood Level; Major Clinical Study; Male; Peritoneal Dialysis; Potassium Blood Level; Sodium Blood Level; Triacylglycerol Blood Level; Urea Blood Levelen_US
dc.titleA comparative study of the effect of icodextrin based peritoneal dialysis and hemodialysis on lipid metabolismen_US
dc.typeArticleen_US

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