Induction of micronuclei and nuclear abnormalities in erythrocytes of mosquito fish (Gambusia affinis) following exposure to the pyrethroid insecticide lambda-cyhalothrin

dc.authoridGokalp, Fulya Dilek/0000-0001-8219-6657
dc.authorid/0000-0003-4135-2486
dc.authorwosid/A-1666-2016
dc.contributor.authorMuranli, Fulya Dilek Gokalp
dc.contributor.authorGuner, Utku
dc.date.accessioned2024-06-12T11:02:26Z
dc.date.available2024-06-12T11:02:26Z
dc.date.issued2011
dc.departmentTrakya Üniversitesien_US
dc.description.abstractIn the present study the induction of micronuclei (MN) and nuclear abnormalities (NA) in erythrocytes of mosquitofish (Gambusia affinis) (Baird & Girard 1853) was studied. Fish were exposed to three different concentrations of lambda-cyhalothrin (LCT) (1 x 10(-4) mu g/l, 2 x 10(-4) mu g/l, 4 x 10(-4) mu g/l) for periods of 6, 12, 24, and 48 h. NA (notched, lobed, blebbed nuclei), MN, bi-nucleated cells, and the ratio of polychromatic erythrocytes (PCEs) to normochromatic erythrocytes (NCEs) were evaluated to assess genotoxicity and cytotoxicity. LCT significantly induced MN and NA in erythrocytes of G. affinis. The PCE/NCE ratio was also decreased after 24- and 48-h treatments of 4 x 10(-4) mu g/l LCT. The results show that LCT has genotoxic and cytotoxic potential on G. affinis. (C) 2011 Elsevier B.V. All rights reserved.en_US
dc.identifier.doi10.1016/j.mrgentox.2011.05.004
dc.identifier.endpage108en_US
dc.identifier.issn1383-5718
dc.identifier.issn1879-3592
dc.identifier.issue2en_US
dc.identifier.pmid21620996en_US
dc.identifier.scopus2-s2.0-81055155963en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage104en_US
dc.identifier.urihttps://doi.org/10.1016/j.mrgentox.2011.05.004
dc.identifier.urihttps://hdl.handle.net/20.500.14551/21283
dc.identifier.volume726en_US
dc.identifier.wosWOS:000298204900004en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevier Science Bven_US
dc.relation.ispartofMutation Research-Genetic Toxicology And Environmental Mutagenesisen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectGambusia Affinisen_US
dc.subjectLambda-Cyhalothrinen_US
dc.subjectMicronucleusen_US
dc.subjectNuclear Abnormalitiesen_US
dc.subjectGenotoxicityen_US
dc.subjectRat Bone-Marrowen_US
dc.subjectAcute Toxicityen_US
dc.subjectRainbow-Trouten_US
dc.subjectPeripheral Erythrocytesen_US
dc.subjectPimephales-Promelasen_US
dc.subjectAquatic Organismsen_US
dc.subjectMill Effluenten_US
dc.subjectMitomycin-Cen_US
dc.subjectIn-Situen_US
dc.subjectCellsen_US
dc.titleInduction of micronuclei and nuclear abnormalities in erythrocytes of mosquito fish (Gambusia affinis) following exposure to the pyrethroid insecticide lambda-cyhalothrinen_US
dc.typeArticleen_US

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