Comparison of dexmedetomidine and lidocaine in the prevention of rocuronium injection pain

Basit Öğe Kaydı
dc.authorscopusid7004931815
dc.authorscopusid7003369853
dc.authorscopusid7004533485
dc.authorscopusid7003311524
dc.authorscopusid7005822791
dc.authorscopusid6701467427
dc.contributor.authorKaya G.
dc.contributor.authorMemiş D.
dc.contributor.authorTuran A.
dc.contributor.authorKaramanlio?lu B.
dc.contributor.authorŞeker Ş.
dc.contributor.authorPamukçu Z.
dc.date.accessioned2024-06-12T10:28:59Z
dc.date.available2024-06-12T10:28:59Z
dc.date.issued2004
dc.description.abstractIn our study, we aimed to compare the efficacy of dexmedetomidine which is an ?-adrenergic receptor agonist and an analgesic,in the prevention of rocuronium injection pain with lidocaine. Following the ethical committee approval and written informed consent, 90 patients (ASA I-II) were randomly divided into three groups. All groups received standard premedication. The patients were monitored and then a tourniquet was applied on the medication-receiving arm and inflated up to 70 mmHg. Group S (n=30) received 1 mL saline, Group L (n=30) received 20 mg lidocaine and Group D (n=30) received, 0.25 mgkg-1 dexmedetomidine intravenously. The tournique was deflated after 20 seconds. Following deflation 1/8 of the total rocuronium dose of 0.9 mg kg-1 was injected and the patients were asked immediately if they had any pain with injection and pain scores were recorded. Then anaesthesia induction was performed and the remaining dose of rocuronim was intevenously injected. Anaesthesia was continued with sevoflurane 1-2 % in 50 % N 2O/O2 mixture. Group L pain scores were lower than Groups S and D with statistical significance (p<0.05, p<0.01, p<0.001). No statistically significant difference was determined between Group D and Group S (p<0.05), although the scores were lower in Group D. In conclusion, it was revealed that lidocaine is effective in preventing pain with rocuronium injection, whereas dexmedetomidine had no significant effect.en_US
dc.identifier.endpage348en_US
dc.identifier.issn1304-0871
dc.identifier.issue5en_US
dc.identifier.scopus2-s2.0-9144252191en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage344en_US
dc.identifier.urihttps://hdl.handle.net/20.500.14551/17528
dc.identifier.volume32en_US
dc.indekslendigikaynakScopusen_US
dc.language.isotren_US
dc.relation.ispartofTurk Anesteziyoloji ve Reanimasyon Dernegi Dergisien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectDexmedetomidine; Injection Pain; Lidocaine; Rocuroniumen_US
dc.subjectDexmedetomidine; Lidocaine; Rocuronium; Sevoflurane; Adult; Anesthesia Induction; Article; Controlled Study; Dose Response; Drug Efficacy; Female; Human; Injection Pain; Major Clinical Study; Male; Pain Assessmenten_US
dc.titleComparison of dexmedetomidine and lidocaine in the prevention of rocuronium injection painen_US
dc.title.alternativeRokuronyum enjeksiyon a?risimn önlenmesinde deksmedetomidin i?le lidokainin karşilaştirilmasien_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

Scopus İndeksli Yayınlar Koleksiyonu