Comparison of dexmedetomidine and lidocaine in the prevention of rocuronium injection pain
Küçük Resim Yok
Tarih
2004
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
In our study, we aimed to compare the efficacy of dexmedetomidine which is an ?-adrenergic receptor agonist and an analgesic,in the prevention of rocuronium injection pain with lidocaine. Following the ethical committee approval and written informed consent, 90 patients (ASA I-II) were randomly divided into three groups. All groups received standard premedication. The patients were monitored and then a tourniquet was applied on the medication-receiving arm and inflated up to 70 mmHg. Group S (n=30) received 1 mL saline, Group L (n=30) received 20 mg lidocaine and Group D (n=30) received, 0.25 mgkg-1 dexmedetomidine intravenously. The tournique was deflated after 20 seconds. Following deflation 1/8 of the total rocuronium dose of 0.9 mg kg-1 was injected and the patients were asked immediately if they had any pain with injection and pain scores were recorded. Then anaesthesia induction was performed and the remaining dose of rocuronim was intevenously injected. Anaesthesia was continued with sevoflurane 1-2 % in 50 % N 2O/O2 mixture. Group L pain scores were lower than Groups S and D with statistical significance (p<0.05, p<0.01, p<0.001). No statistically significant difference was determined between Group D and Group S (p<0.05), although the scores were lower in Group D. In conclusion, it was revealed that lidocaine is effective in preventing pain with rocuronium injection, whereas dexmedetomidine had no significant effect.
Açıklama
Anahtar Kelimeler
Dexmedetomidine; Injection Pain; Lidocaine; Rocuronium, Dexmedetomidine; Lidocaine; Rocuronium; Sevoflurane; Adult; Anesthesia Induction; Article; Controlled Study; Dose Response; Drug Efficacy; Female; Human; Injection Pain; Major Clinical Study; Male; Pain Assessment
Kaynak
Turk Anesteziyoloji ve Reanimasyon Dernegi Dergisi
WoS Q Değeri
Scopus Q Değeri
N/A
Cilt
32
Sayı
5
