The predictive role of HbA1c and previous medications in initiation of insulin treatment

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dc.contributor.authorDemirci, Hakan
dc.contributor.authorCinar, Yildirim
dc.date.accessioned2024-06-12T11:22:59Z
dc.date.available2024-06-12T11:22:59Z
dc.date.issued2010
dc.departmentTrakya Üniversitesien_US
dc.description.abstractINTRODUCTION: Subjects (n = 46) with type 2 diabetes who responded inadequately to two and three oral medications (HbA(1C) > 8.0%) were consecutively recruited for treatment with premixed insulin 30/70 two times a day in order to investigate whether previous oral therapies may predict insulin requirements. MATERIAL AND METHODS: In this prospective study, men and women were eligible to participate if they were aged between 30 and 65 years, had had a diagnosis of type 2 diabetes mellitus for at least 12 months, were insulin-naive and had been treated unsuccessfully with either two or three oral antidiabetic drugs for at minimum of three months. Clinical and laboratory findings were analyzed at one year follow-up. RESULTS: The average required insulin doses were significantly higher in patients in whom previous triple oral medication had failed than in patients in whom two oral drugs had failed. CONCLUSIONS: Evaluation of the previous number of oral antidiabetic drugs and HbA(1C) values may help us predict the insulin requirement when oral drugs have failed.en_US
dc.identifier.issn0907-8916
dc.identifier.issn1603-9629
dc.identifier.issue11en_US
dc.identifier.pmid21055372en_US
dc.identifier.scopus2-s2.0-78649529853en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.urihttps://hdl.handle.net/20.500.14551/26176
dc.identifier.volume57en_US
dc.identifier.wosWOS:000283994900005en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherDanish Medical Assocen_US
dc.relation.ispartofDanish Medical Bulletinen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subject[No Keywords]en_US
dc.titleThe predictive role of HbA1c and previous medications in initiation of insulin treatmenten_US
dc.typeArticleen_US

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