The predictive role of HbA1c and previous medications in initiation of insulin treatment
Küçük Resim Yok
Tarih
2010
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Danish Medical Assoc
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
INTRODUCTION: Subjects (n = 46) with type 2 diabetes who responded inadequately to two and three oral medications (HbA(1C) > 8.0%) were consecutively recruited for treatment with premixed insulin 30/70 two times a day in order to investigate whether previous oral therapies may predict insulin requirements. MATERIAL AND METHODS: In this prospective study, men and women were eligible to participate if they were aged between 30 and 65 years, had had a diagnosis of type 2 diabetes mellitus for at least 12 months, were insulin-naive and had been treated unsuccessfully with either two or three oral antidiabetic drugs for at minimum of three months. Clinical and laboratory findings were analyzed at one year follow-up. RESULTS: The average required insulin doses were significantly higher in patients in whom previous triple oral medication had failed than in patients in whom two oral drugs had failed. CONCLUSIONS: Evaluation of the previous number of oral antidiabetic drugs and HbA(1C) values may help us predict the insulin requirement when oral drugs have failed.
Açıklama
Anahtar Kelimeler
[No Keywords]
Kaynak
Danish Medical Bulletin
WoS Q Değeri
Q2
Scopus Q Değeri
N/A
Cilt
57
Sayı
11
