Microwave ablation of autonomously functioning thyroid nodules: a comparative study with radioactive iodine therapy on the functional treatment success

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dc.authoridErtürk, Mehmet Sercan/0000-0002-0411-553X
dc.authoridCelik, Mehmet/0000-0001-7364-370X
dc.authorwosidErtürk, Mehmet Sercan/AFS-7683-2022
dc.authorwosidCelik, Mehmet/AAA-8773-2021
dc.contributor.authorErturk, Mehmet Sercan
dc.contributor.authorCekic, Bulent
dc.contributor.authorCelik, Mehmet
dc.contributor.authorUguz, Isil Demiray
dc.date.accessioned2024-06-12T11:16:26Z
dc.date.available2024-06-12T11:16:26Z
dc.date.issued2021
dc.departmentTrakya Üniversitesien_US
dc.description.abstractIntroduction: The objective of this study was to compare the efficiency of microwave ablation (MWA) and radioactive iodine (RAI) in the treatment of toxic adenoma (TA), and to investigate the functional treatment success of the used modalities for its remission. Material and methods: Treatment outcomes - thyroid hormone levels and nodule characteristics - of 30 patients (23:7 F:M; 52.77 +/- 11.13 years) treated by MWA were compared with the those of 35 patients (24:11 F:M; 61.43 +/- 12.60 years) treated by RAI. The baseline characteristics of TAs, which are gender and pre volume, were analogous and did not show any statistical significance (p > 0.05). Thyroid hormone levels of patients treated with two different methods were measured after 9 months, and the obtained results were compared. Results: Although there was no statistically significant difference in the nodule volume (p > 0.05), there was a greater volume reduction rate (VRR%) in the group treated with MWA rather than RAI (p < 0.05) at the end of the follow-up. In the MWA group, there was a higher increase in FT3 than in the RAI group (p < 0.05). Furthermore, no statistically significant difference in TSH (p = 0.124) and FT4 (p = 0.144) levels of the patients as treatment outcomes was observed. The therapeutic success was accomplished in 18/30 (60%) of the MWA group and in 24/35 (68.6%) of the RAI group. Conclusions: Therapeutic success of MWA and RAI did not show any statistically significant difference (p = 0.471). However, the development of hypothyroidism in 7 of 35 patients treated with RAI was observed. On the other hand, no case of post-treatment hypothyroidism was observed in patients treated with MWA. In this regard, MWA could be a great alternative to RAI due to its advantages in terms of non-exposure to radiation and lower risk of post-treatment hypothyroidism.en_US
dc.identifier.doi10.5603/EP.a2020.0088
dc.identifier.endpage125en_US
dc.identifier.issn0423-104X
dc.identifier.issue2en_US
dc.identifier.pmid33619707en_US
dc.identifier.scopus2-s2.0-85106389153en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage120en_US
dc.identifier.urihttps://doi.org/10.5603/EP.a2020.0088
dc.identifier.urihttps://hdl.handle.net/20.500.14551/24300
dc.identifier.volume72en_US
dc.identifier.wosWOS:000651036300006en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherVia Medicaen_US
dc.relation.ispartofEndokrynologia Polskaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectThyroiden_US
dc.subjectNoduleen_US
dc.subjectToxic Adenomaen_US
dc.subjectMicrowave Ablationen_US
dc.subjectThyroid Hormonesen_US
dc.subjectPercutaneous Ethanol Injectionen_US
dc.subjectRadiofrequency Ablationen_US
dc.subjectFollow-Upen_US
dc.subjectHyperthyroidismen_US
dc.subjectRadioiodineen_US
dc.subjectPrevalenceen_US
dc.subjectGuidelinesen_US
dc.subjectDiseaseen_US
dc.subjectSurgeryen_US
dc.subjectSafetyen_US
dc.titleMicrowave ablation of autonomously functioning thyroid nodules: a comparative study with radioactive iodine therapy on the functional treatment successen_US
dc.typeArticleen_US

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