Microwave ablation of autonomously functioning thyroid nodules: a comparative study with radioactive iodine therapy on the functional treatment success
Küçük Resim Yok
Tarih
2021
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Via Medica
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Introduction: The objective of this study was to compare the efficiency of microwave ablation (MWA) and radioactive iodine (RAI) in the treatment of toxic adenoma (TA), and to investigate the functional treatment success of the used modalities for its remission. Material and methods: Treatment outcomes - thyroid hormone levels and nodule characteristics - of 30 patients (23:7 F:M; 52.77 +/- 11.13 years) treated by MWA were compared with the those of 35 patients (24:11 F:M; 61.43 +/- 12.60 years) treated by RAI. The baseline characteristics of TAs, which are gender and pre volume, were analogous and did not show any statistical significance (p > 0.05). Thyroid hormone levels of patients treated with two different methods were measured after 9 months, and the obtained results were compared. Results: Although there was no statistically significant difference in the nodule volume (p > 0.05), there was a greater volume reduction rate (VRR%) in the group treated with MWA rather than RAI (p < 0.05) at the end of the follow-up. In the MWA group, there was a higher increase in FT3 than in the RAI group (p < 0.05). Furthermore, no statistically significant difference in TSH (p = 0.124) and FT4 (p = 0.144) levels of the patients as treatment outcomes was observed. The therapeutic success was accomplished in 18/30 (60%) of the MWA group and in 24/35 (68.6%) of the RAI group. Conclusions: Therapeutic success of MWA and RAI did not show any statistically significant difference (p = 0.471). However, the development of hypothyroidism in 7 of 35 patients treated with RAI was observed. On the other hand, no case of post-treatment hypothyroidism was observed in patients treated with MWA. In this regard, MWA could be a great alternative to RAI due to its advantages in terms of non-exposure to radiation and lower risk of post-treatment hypothyroidism.
Açıklama
Anahtar Kelimeler
Thyroid, Nodule, Toxic Adenoma, Microwave Ablation, Thyroid Hormones, Percutaneous Ethanol Injection, Radiofrequency Ablation, Follow-Up, Hyperthyroidism, Radioiodine, Prevalence, Guidelines, Disease, Surgery, Safety
Kaynak
Endokrynologia Polska
WoS Q Değeri
Q4
Scopus Q Değeri
Q3
Cilt
72
Sayı
2
