Assessment of in vitro Antioxidant and Antidiabetic Capacities of Medlar (Mespilus germanica)

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dc.contributor.authorIsbilir, Sebnem Selen
dc.contributor.authorKabala, Sevilay Inal
dc.contributor.authorYagar, Hulya
dc.date.accessioned2024-06-12T10:51:30Z
dc.date.available2024-06-12T10:51:30Z
dc.date.issued2019
dc.departmentTrakya Üniversitesien_US
dc.description.abstractThe objective of the current study was to evaluate the antioxidant activity and enzyme inhibitory effect of different parts of medlar including fruit, leaf and flower bud by using various in vitro methods, and also determination of total phenolic and flavonoid content in the samples. Ethanol extracts of medlar parts were prepared and their antioxidant activities were determined using 1,1-diphenyl-2-picryl-hydrazil (DPPH center dot) scavenging and beta-carotene bleaching methods. The leaf extract showed the strongest antioxidant activity. DPPH radical scavenging activity was in the order of BHA > leaf > bud > fruit. This ordering was the same for beta-carotene bleaching activity, tocopherol > leaf > bud > fruit. The highest total phenolic (60.3 +/- 1.69 mg GAE g(-1) extract) and flavonoid (14.77 +/- 1.15 mg QE g(-1 )extract) content were determined in leaf extract. For possible antidiabetic effects of extracts, alpha-amylase and alpha-glucosidase inhibitory activities were investigated, the bud extract showed the highest inhibition activities among the all extracts.en_US
dc.identifier.doi10.15835/nbha47211325
dc.identifier.endpage389en_US
dc.identifier.issn0255-965X
dc.identifier.issn1842-4309
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-85071087999en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage384en_US
dc.identifier.urihttps://doi.org/10.15835/nbha47211325
dc.identifier.urihttps://hdl.handle.net/20.500.14551/18388
dc.identifier.volume47en_US
dc.identifier.wosWOS:000454169000016en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherUniv Agr Sci & Veterinary Med Cluj-Napocaen_US
dc.relation.ispartofNotulae Botanicae Horti Agrobotanici Cluj-Napocaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAmylase Inhibitionen_US
dc.subjectDPPH Scavengingen_US
dc.subjectGlucosidase Inhibitionen_US
dc.subjectMedlar Leafen_US
dc.subjectPhenolic Contenten_US
dc.subjectAlpha-Glucosidaseen_US
dc.subjectFree-Radicalsen_US
dc.subjectL. Fruiten_US
dc.subjectExtractsen_US
dc.subjectAmylaseen_US
dc.subjectHealthen_US
dc.subjectPartsen_US
dc.subjectAcidsen_US
dc.titleAssessment of in vitro Antioxidant and Antidiabetic Capacities of Medlar (Mespilus germanica)en_US
dc.typeArticleen_US

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