Assessment of in vitro Antioxidant and Antidiabetic Capacities of Medlar (Mespilus germanica)

Küçük Resim Yok

Tarih

2019

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Univ Agr Sci & Veterinary Med Cluj-Napoca

Erişim Hakkı

info:eu-repo/semantics/closedAccess

Özet

The objective of the current study was to evaluate the antioxidant activity and enzyme inhibitory effect of different parts of medlar including fruit, leaf and flower bud by using various in vitro methods, and also determination of total phenolic and flavonoid content in the samples. Ethanol extracts of medlar parts were prepared and their antioxidant activities were determined using 1,1-diphenyl-2-picryl-hydrazil (DPPH center dot) scavenging and beta-carotene bleaching methods. The leaf extract showed the strongest antioxidant activity. DPPH radical scavenging activity was in the order of BHA > leaf > bud > fruit. This ordering was the same for beta-carotene bleaching activity, tocopherol > leaf > bud > fruit. The highest total phenolic (60.3 +/- 1.69 mg GAE g(-1) extract) and flavonoid (14.77 +/- 1.15 mg QE g(-1 )extract) content were determined in leaf extract. For possible antidiabetic effects of extracts, alpha-amylase and alpha-glucosidase inhibitory activities were investigated, the bud extract showed the highest inhibition activities among the all extracts.

Açıklama

Anahtar Kelimeler

Amylase Inhibition, DPPH Scavenging, Glucosidase Inhibition, Medlar Leaf, Phenolic Content, Alpha-Glucosidase, Free-Radicals, L. Fruit, Extracts, Amylase, Health, Parts, Acids

Kaynak

Notulae Botanicae Horti Agrobotanici Cluj-Napoca

WoS Q Değeri

Q3

Scopus Q Değeri

Q2

Cilt

47

Sayı

2

Künye