THE PROTECTIVE EFFECT OF MOCLOBEMIDE AGAINST HYPOXIA-INDUCED LETHALITY IN MICE IS NOT DUE TO A DECREASE IN BODY-TEMPERATURE

Basit Öğe Kaydı
dc.authoridUlugol, Ahmet/0000-0003-4643-1124
dc.authoridKaradag, Cetin Hakan/0000-0002-4763-986X
dc.authorwosidUlugol, Ahmet/V-9665-2019
dc.authorwosidKaradag, Cetin Hakan/H-4899-2013
dc.contributor.authorULUGOL, A
dc.contributor.authorKARADAG, HC
dc.contributor.authorDOKMECI, D
dc.contributor.authorALKHATIB, I
dc.contributor.authorDOKMECI, I
dc.date.accessioned2024-06-12T11:08:40Z
dc.date.available2024-06-12T11:08:40Z
dc.date.issued1995
dc.departmentTrakya Üniversitesien_US
dc.description.abstractThe protective effect of moclobemide, a reversible and highly selective inhibitor of monoamine oxidase-A, against hypoxia-induced lethality was investigated in the present experiment. Moclobemide showed an apparent protective potency against hypoxia and significantly prolonged the latencies for convulsions and death in a dose-dependent manner. Hypothermia is known to protect animals from hypoxia. Moclobemide also decreased body temperature in mice; however, the hypothermic effect was unrelated to the antihypoxic effect. These results suggest that the protective effect of moclobemide in hypoxia is not due to a decrease in body temperature.en_US
dc.identifier.doi10.1016/0091-3057(94)00366-Q
dc.identifier.endpage247en_US
dc.identifier.issn0091-3057
dc.identifier.issue2-3en_US
dc.identifier.pmid7667335en_US
dc.identifier.scopus2-s2.0-0029042334en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage245en_US
dc.identifier.urihttps://doi.org/10.1016/0091-3057(94)00366-Q
dc.identifier.urihttps://hdl.handle.net/20.500.14551/22510
dc.identifier.volume51en_US
dc.identifier.wosWOS:A1995RB49100012en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherPergamon-Elsevier Science Ltden_US
dc.relation.ispartofPharmacology Biochemistry And Behavioren_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectMOCLOBEMIDEen_US
dc.subjectHYPOXIAen_US
dc.subjectBODY TEMPERATUREen_US
dc.subjectOxidase Type-Aen_US
dc.subjectBarbiturate Protectionen_US
dc.subjectReversible Inhibitoren_US
dc.subjectHypothermiaen_US
dc.subjectPharmacologyen_US
dc.subjectProfileen_US
dc.subjectDrugsen_US
dc.titleTHE PROTECTIVE EFFECT OF MOCLOBEMIDE AGAINST HYPOXIA-INDUCED LETHALITY IN MICE IS NOT DUE TO A DECREASE IN BODY-TEMPERATUREen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu