Antibacterial, antifungal and antimycobacterial activities of some pyrazoline, hydrazone and chalcone derivatives

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dc.authorwosidONURDAG, Fatma KAYNAK/T-2518-2017
dc.contributor.authorEvranos-Aksoz, Begum
dc.contributor.authorOnurdag, Fatma Kaynak
dc.contributor.authorOzgacar, Selda Ozgen
dc.date.accessioned2024-06-12T10:56:08Z
dc.date.available2024-06-12T10:56:08Z
dc.date.issued2015
dc.departmentTrakya Üniversitesien_US
dc.description.abstractTwenty-seven previously reported chalcones and their pyrazoline and hydrazone derivatives as well as two further chalcones have been screened for their antimicrobial, antifungal and antimycobacterial activities against standard microbial strains and drug resistant isolates. The minimum inhibitory concentration (MIC) value of each compound was determined by a two-fold serial microdilution technique. The compounds were found to possess a broad spectrum of antimicrobial activities with MIC values of 8-128 mu g/mL. One compound [(E)-1(4-hydroxyphenyl)-3-p-tolylprop-2-en-1-one] had equal activity with gentamycin (8 mu g/mL) against Enterococcus faecalis. Chalcones were found to be more active than their hydrazone and 2-pyrazoline derivatives against Staphylococcus aureus ATCC 29213 and E. faecalis ATCC 29212.en_US
dc.identifier.doi10.1515/znc-2014-4195
dc.identifier.endpage189en_US
dc.identifier.issn0939-5075
dc.identifier.issn1865-7125
dc.identifier.issue7-8en_US
dc.identifier.pmid26372110en_US
dc.identifier.scopus2-s2.0-84946837435en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage183en_US
dc.identifier.urihttps://doi.org/10.1515/znc-2014-4195
dc.identifier.urihttps://hdl.handle.net/20.500.14551/19686
dc.identifier.volume70en_US
dc.identifier.wosWOS:000366255800003en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWalter De Gruyter Gmbhen_US
dc.relation.ispartofZeitschrift Fur Naturforschung Section C-A Journal Of Biosciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectChalconesen_US
dc.subjectHydrazonesen_US
dc.subject2-Pyrazolinesen_US
dc.subjectMonoamine-Oxidaseen_US
dc.subjectAmine Oxidaseen_US
dc.subjectIn-Vitroen_US
dc.subjectInhibitory Propertiesen_US
dc.subjectEscherichia-Colien_US
dc.subjectCrystallizationen_US
dc.subjectPurificationen_US
dc.subjectTuberculosisen_US
dc.titleAntibacterial, antifungal and antimycobacterial activities of some pyrazoline, hydrazone and chalcone derivativesen_US
dc.typeArticleen_US

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