Prevalence of extended-spectrum beta-lactamases produced by nosocomial isolates of Enterobacteriaceae in Trakya University Hospital, Turkey

dc.contributor.authorAkata, F
dc.contributor.authorTatman-Otkun, M
dc.contributor.authorÖzkan, E
dc.contributor.authorTansel, Ö
dc.contributor.authorOtkun, M
dc.contributor.authorTugrul, M
dc.date.accessioned2024-06-12T11:00:26Z
dc.date.available2024-06-12T11:00:26Z
dc.date.issued2003
dc.departmentTrakya Üniversitesien_US
dc.description.abstractThe prevalence of extended-spectrum beta-lactamase (ESBL) production by 194 nosocomial isolates of Enterobacteriacea recovered from 1995 to 1999 was investigated. The ESBL production was determined by the double-disk synergy test and was confirmed by the E-test ESBL strip. Twenty-three isolates (21 Klebsiella pneumoniae, one Escherichia coli, one Providencia rettgeri) were found as ES-BL-producers (11.8%). These isolates were also usually resistant to non-betalactam antibiotics. Most of them contained a beta-lactamase with a pI of 7.6. All the strains conjugally transferred their ESBLs to recipient E.coli. Contrary to others, ESBL-producing K.pneumoniae strains isolated in 1999 were resistant to ciprofloxacin, and had the identical plasmid profiles suggestive of an outbreak. Ciprofloxacin resistance in these strains could not be transferred. In conclusion, K. pneumoniae was the main ESBL-producing species among nosocomial isolates of Enterobacteriacae in our hospital.en_US
dc.identifier.endpage262en_US
dc.identifier.issn1121-7138
dc.identifier.issue3en_US
dc.identifier.pmid12901421en_US
dc.identifier.scopus2-s2.0-0142008883en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage257en_US
dc.identifier.urihttps://hdl.handle.net/20.500.14551/20835
dc.identifier.volume26en_US
dc.identifier.wosWOS:000184437500004en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherLuigi Ponzio E Figlioen_US
dc.relation.ispartofMicrobiologicaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectEnterobacteriaceaeen_US
dc.subjectKlebsiella Pneumoniaeen_US
dc.subjectESBLen_US
dc.subjectIsoelectric Pointen_US
dc.subjectPlasmiden_US
dc.subjectIntensive-Care Unitsen_US
dc.subjectResistanceen_US
dc.subjectEpidemiologyen_US
dc.subjectBacteremiaen_US
dc.subjectInfectionsen_US
dc.subjectKlebsiellaen_US
dc.subjectStrainsen_US
dc.subjectPlasmiden_US
dc.titlePrevalence of extended-spectrum beta-lactamases produced by nosocomial isolates of Enterobacteriaceae in Trakya University Hospital, Turkeyen_US
dc.typeArticleen_US

Dosyalar