Prevalence of extended-spectrum beta-lactamases produced by nosocomial isolates of Enterobacteriaceae in Trakya University Hospital, Turkey
Küçük Resim Yok
Tarih
2003
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Luigi Ponzio E Figlio
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
The prevalence of extended-spectrum beta-lactamase (ESBL) production by 194 nosocomial isolates of Enterobacteriacea recovered from 1995 to 1999 was investigated. The ESBL production was determined by the double-disk synergy test and was confirmed by the E-test ESBL strip. Twenty-three isolates (21 Klebsiella pneumoniae, one Escherichia coli, one Providencia rettgeri) were found as ES-BL-producers (11.8%). These isolates were also usually resistant to non-betalactam antibiotics. Most of them contained a beta-lactamase with a pI of 7.6. All the strains conjugally transferred their ESBLs to recipient E.coli. Contrary to others, ESBL-producing K.pneumoniae strains isolated in 1999 were resistant to ciprofloxacin, and had the identical plasmid profiles suggestive of an outbreak. Ciprofloxacin resistance in these strains could not be transferred. In conclusion, K. pneumoniae was the main ESBL-producing species among nosocomial isolates of Enterobacteriacae in our hospital.
Açıklama
Anahtar Kelimeler
Enterobacteriaceae, Klebsiella Pneumoniae, ESBL, Isoelectric Point, Plasmid, Intensive-Care Units, Resistance, Epidemiology, Bacteremia, Infections, Klebsiella, Strains, Plasmid
Kaynak
Microbiologica
WoS Q Değeri
Q4
Scopus Q Değeri
Q3
Cilt
26
Sayı
3
