Factors related to exercise capacity in asymptomatic middle-aged type 2 diabetic patients

dc.authoridAltun, Armagan/0000-0002-3233-8263
dc.authorwosidAltun, Armagan/ABB-5844-2020
dc.contributor.authorUgur-Altun, B
dc.contributor.authorAltun, A
dc.contributor.authorTatli, E
dc.contributor.authorTugrul, A
dc.date.accessioned2024-06-12T11:16:51Z
dc.date.available2024-06-12T11:16:51Z
dc.date.issued2005
dc.departmentTrakya Üniversitesien_US
dc.description.abstractAim: We aimed to look at the relationship between exercise capacity and metabolic variables in unselected consecutive asymptomatic middle-aged type 2 diabetic patients as a potential marker for undiagnosed coronary heart disease. Method: Ninety patients (49 6 years) were included in the study. All patients performed a treadmill exercise test using the Bruce protocol. According to achieved EC, patients were separated into three groups; Group I (n, 24) 8 > metabolic equivalents (METs) greater than or equal to 5, Group II (n, 54) 11 > METs > 8 and Group III (n, 12) METs > 11. Results: Patients in group I are more likely to be of female gender and to have a family history of coronary heart disease (CHD) than in group III (P = 0.015, P = 0.009, respectively). When compared to group 111, patients in group I had higher fasting insulin and fibrinogen levels (P = 0.049 and P = 0.01, respectively). Homeostasis model assessment for insulin resistance (HOMA-IR) index (P = 0.03) was also higher in group I than in group III. We found a significant negative correlation between achieved exercise capacity and age (r = -0.204, P = 0.048), fasting insulin (r = -0.209, P = 0.048), HOMA-IR (r = -0.204, P = 0.048) as well as fibrinogen (r = -0.301, P = 0.007). Conclusion: Reduced exercise capacity was associated with increased insulin resistance as assessed by HOMA-IR index in asymptornatic middle-aged type 2 diabetic patients. (C) 2004 Elsevier Ireland Ltd. All rights reserved.en_US
dc.identifier.doi10.1016/j.diabres.2004.06.005
dc.identifier.endpage136en_US
dc.identifier.issn0168-8227
dc.identifier.issn1872-8227
dc.identifier.issue2en_US
dc.identifier.pmid15649572en_US
dc.identifier.scopus2-s2.0-11844252642en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage130en_US
dc.identifier.urihttps://doi.org/10.1016/j.diabres.2004.06.005
dc.identifier.urihttps://hdl.handle.net/20.500.14551/24480
dc.identifier.volume67en_US
dc.identifier.wosWOS:000226612700005en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevier Ireland Ltden_US
dc.relation.ispartofDiabetes Research And Clinical Practiceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectType 2 Diabetesen_US
dc.subjectExercise Testen_US
dc.subjectExercise Capacityen_US
dc.subjectInsulin Resistanceen_US
dc.subjectHeart-Rate Recoveryen_US
dc.subjectPrognostic Valueen_US
dc.subjectInsulin Sensitivityen_US
dc.subjectFollow-Upen_US
dc.subjectAll-Causeen_US
dc.subjectMortalityen_US
dc.subjectPredictoren_US
dc.subjectHyperinsulinemiaen_US
dc.subjectAssociationen_US
dc.subjectDysfunctionen_US
dc.titleFactors related to exercise capacity in asymptomatic middle-aged type 2 diabetic patientsen_US
dc.typeArticleen_US

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