Trypsin-catalyzed peptide synthesis in acetonitrile with low water content

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dc.contributor.authorYesiloglu, Y
dc.contributor.authorSagiroglu, A
dc.date.accessioned2024-06-12T11:12:17Z
dc.date.available2024-06-12T11:12:17Z
dc.date.issued2002
dc.departmentTrakya Üniversitesien_US
dc.description.abstractTrypsin was immobilized to alumina by adsorption from its aqueous solutions. The activity of trypsin was increased by immobilization for peptide synthesis. With these immobilized enzymes Bz-Arg-Leu-NH2 dipeptide synthesis was carried out. Iso amylalcohol, tetrahydrofuran and acetonitrile were used as solvents giving the highest yield in the peptide formation reaction. The yield of the peptide was strongly dependent on water content in the reaction medium. The stability of alumina-immobilized trypsin is described.en_US
dc.identifier.endpage534en_US
dc.identifier.issn1300-0527
dc.identifier.issue4en_US
dc.identifier.scopus2-s2.0-0036347164en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage529en_US
dc.identifier.trdizinid32493en_US
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/32493
dc.identifier.urihttps://hdl.handle.net/20.500.14551/23093
dc.identifier.volume26en_US
dc.identifier.wosWOS:000176397800009en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.publisherTubitak Scientific & Technological Research Council Turkeyen_US
dc.relation.ispartofTurkish Journal Of Chemistryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectPeptide Synthesis Trypsinen_US
dc.subjectImmobilizationen_US
dc.subjectOrganic Solventen_US
dc.subjectAluminaen_US
dc.subjectImmobilizationen_US
dc.titleTrypsin-catalyzed peptide synthesis in acetonitrile with low water contenten_US
dc.typeArticleen_US

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