Does the efficacy of supplemental oxygen for the prevention of postoperative nausea and vomiting depend on the measured outcome, observational period or site of surgery?

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dc.contributor.authorTuran, A.
dc.contributor.authorApfel, C. C.
dc.contributor.authorKumpch, M.
dc.contributor.authorDanzeisen, O.
dc.contributor.authorEberhart, L. H. J.
dc.contributor.authorForst, H.
dc.contributor.authorHeringhaus, C.
dc.date.accessioned2024-06-12T11:18:39Z
dc.date.available2024-06-12T11:18:39Z
dc.date.issued2006
dc.departmentTrakya Üniversitesien_US
dc.description.abstractHigh intra-operative oxygen concentration reportedly reduces postoperative nausea and vomiting (PONV), but recent data are conflicting. Therefore, we tested whether the effectiveness of supplemental oxygen depends on the endpoint (nausea vs. vomiting), observation interval (early vs. late) or surgical field (abdominal vs. non-abdominal). We randomly assigned 560 adult patients undergoing various elective procedures with a PONV risk. of at least 40% to intra-operative 80% (supplemental) or 30% oxygen (control). Potential confounding factors were similar between groups. Incidences of nausea were similar in the groups during early (12% (supplemental) vs. 10% (control), p = 0.43) and late intervals, 26% vs. 20%, p = 0.09, as were the incidences of vomiting (early: 2% vs. 3%, p = 0.40; late: 8% vs. 9%, p = 0.75). Supplemental oxygen was no more effective at reducing PONV in abdominal (40% vs. 31%, p = 0.37) than in non-abdominal surgery (25% vs. 21%, p = 0.368). Thus, supplemental oxygen was unable to reduce PONY independent of the endpoint, observational period or site of surgery.en_US
dc.identifier.doi10.1111/j.1365-2044.2006.04703.x
dc.identifier.endpage633en_US
dc.identifier.issn0003-2409
dc.identifier.issn1365-2044
dc.identifier.issue7en_US
dc.identifier.pmid16792606en_US
dc.identifier.scopus2-s2.0-33745027400en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage628en_US
dc.identifier.urihttps://doi.org/10.1111/j.1365-2044.2006.04703.x
dc.identifier.urihttps://hdl.handle.net/20.500.14551/24895
dc.identifier.volume61en_US
dc.identifier.wosWOS:000238914200002en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofAnaesthesiaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectControlled Trialsen_US
dc.subjectMotion Sicknessen_US
dc.subjectRisk-Factorsen_US
dc.subjectOndansetronen_US
dc.subjectPlaceboen_US
dc.subjectInterventionsen_US
dc.subjectLaparoscopyen_US
dc.subjectSafetyen_US
dc.subjectTraumaen_US
dc.subjectReduceen_US
dc.titleDoes the efficacy of supplemental oxygen for the prevention of postoperative nausea and vomiting depend on the measured outcome, observational period or site of surgery?en_US
dc.typeArticleen_US

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