The comparison of the effects of bupivacaine+morphine and bupivacaine+clonidine in vertebral surgery

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dc.authorscopusid6603397675
dc.authorscopusid6507871432
dc.authorscopusid7003369853
dc.authorscopusid6602623149
dc.authorscopusid6701467427
dc.contributor.authorAlagol A.
dc.contributor.authorEvis M.
dc.contributor.authorMemis D.
dc.contributor.authorYalniz E.
dc.contributor.authorPamukcu Z.
dc.date.accessioned2024-06-12T10:28:33Z
dc.date.available2024-06-12T10:28:33Z
dc.date.issued2000
dc.description.abstractIn this study, for postoperative pain management of 40 patients who were operated for lumbal scoliosis, spondylolystesis and spondylolysis, a catheter was placed into the epidural space, during intraoperative period. By this way bupivacaine+morphine or bupivacaine+clonidine were administered and compared for analgesic, haemodynamic and side effects. In all patients premedication, induction and maintenence of anesthesia were similar. After awakening and neurologic examination, in group I, patients received bupivacaine % 0.125+morphine 2 mg; in group II; bupivacaine % 0.125+1 mcg/kg clonidine; in 10 ml volume of % 0.9 NaCl, via the catheter. Pain (NRS), haemodynamic, respiratory and side effects were noted at: the begining of the postoperative period (0. min.), 30. min. and 1., 2., 6., 12. and 24. hours respectively. 2 mg of morphine was applied from the catheter when needed and total morphine requirements were noted. Data were evaluated statistically; while NRS and haemodynamic results were lower in group II, respiratory values were equal. Analgesia time and side effects were higher in group I. In conclusion, as both combinations were effective and safe in postoperative pain management via an epidural catheter, bupivacaine+clonidine may be an alternative to morphine+bupivacaine.en_US
dc.identifier.endpage49en_US
dc.identifier.issn1300-0012
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-0033863487en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage45en_US
dc.identifier.urihttps://hdl.handle.net/20.500.14551/17290
dc.identifier.volume12en_US
dc.indekslendigikaynakScopusen_US
dc.language.isotren_US
dc.relation.ispartofAgrien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBupivacaine; Clonidine; Epidural Catheter; Morphine; Postoperative Analgesiaen_US
dc.subjectBupivacaine; Clonidine; Morphine; Article; Clinical Article; Drug Effect; Drug Induced Disease; Drug Safety; Epidural Catheter; Hemodynamics; Human; Postoperative Analgesia; Postoperative Pain; Spine Surgeryen_US
dc.titleThe comparison of the effects of bupivacaine+morphine and bupivacaine+clonidine in vertebral surgeryen_US
dc.title.alternativeVertebra cerrahisinde intraoperatif uygulanan epidural kateter ile bupivakain+morfin ve bupivakain+klonidin uygulamasinin karsilastirilmasien_US
dc.typeArticleen_US

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