The comparison of the effects of bupivacaine+morphine and bupivacaine+clonidine in vertebral surgery
Küçük Resim Yok
Tarih
2000
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Yayıncı
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
In this study, for postoperative pain management of 40 patients who were operated for lumbal scoliosis, spondylolystesis and spondylolysis, a catheter was placed into the epidural space, during intraoperative period. By this way bupivacaine+morphine or bupivacaine+clonidine were administered and compared for analgesic, haemodynamic and side effects. In all patients premedication, induction and maintenence of anesthesia were similar. After awakening and neurologic examination, in group I, patients received bupivacaine % 0.125+morphine 2 mg; in group II; bupivacaine % 0.125+1 mcg/kg clonidine; in 10 ml volume of % 0.9 NaCl, via the catheter. Pain (NRS), haemodynamic, respiratory and side effects were noted at: the begining of the postoperative period (0. min.), 30. min. and 1., 2., 6., 12. and 24. hours respectively. 2 mg of morphine was applied from the catheter when needed and total morphine requirements were noted. Data were evaluated statistically; while NRS and haemodynamic results were lower in group II, respiratory values were equal. Analgesia time and side effects were higher in group I. In conclusion, as both combinations were effective and safe in postoperative pain management via an epidural catheter, bupivacaine+clonidine may be an alternative to morphine+bupivacaine.
Açıklama
Anahtar Kelimeler
Bupivacaine; Clonidine; Epidural Catheter; Morphine; Postoperative Analgesia, Bupivacaine; Clonidine; Morphine; Article; Clinical Article; Drug Effect; Drug Induced Disease; Drug Safety; Epidural Catheter; Hemodynamics; Human; Postoperative Analgesia; Postoperative Pain; Spine Surgery
Kaynak
Agri
WoS Q Değeri
Scopus Q Değeri
Q3
Cilt
12
Sayı
1
