Demographic and Clinical Characteristics of Patients With Autosomal Dominant Polycystic Kidney Diseases in Istanbul Faculty of Medicine

Basit Öğe Kaydı
dc.contributor.authorEkin, Büşra
dc.contributor.authorÇörekçioğlu, Büşra
dc.contributor.authorÇiftkaya, Aylin
dc.contributor.authorYazıcı, Halil
dc.contributor.authorEcder, Tevfik
dc.date.accessioned2021-11-20T10:27:13Z
dc.date.available2021-11-20T10:27:13Z
dc.date.issued2015
dc.departmentTrakya Üniversitesien_US
dc.description.abstractAims: Autosomal dominant polycystic kidney disease (ADPKD) is the most common hereditary renal disease which affects about 1 in 400 to 1 in 1000 people worldwide. Therefore it is vital to know the natural course of the disease elaborately. The aim of this study is to assess the demographic and clinical characteristics of patients with Autosomal dominant polycystic kidney disease (ADPKD). Methods: Medical records of 144 patients with Autosomal dominant polycystic kidney disease (ADPKD) wereexamined and the data were acquired from these records. The investigated demographic and clinical characteristics were age, gender, history of smoking, hypertension, types of antihypertensive drugs used, macroscopic hematuria, urinary tract infection, urinary tract stones, renal replacement therapy, cysts found in other organs, and results of the patients’ blood and urine tests such as blood urea nitrogen (BUN), creatinine, cholesterol, albumin, hemoglobin and proteinuria. Patients who had a blood pressure (BP) of 140/90 mmHg or greater and/or using antihypertensive medications were considered as hypertensive.Results: The study included 61 male and 83 female patients. The mean age of patients was 44.9 years. 11.9% of thepatients were smokers whereas 4.2% were ex-smokers. The mean systolic and diastolic blood pressures (BP) were 139.2 mmHg and 89.5 mmHg, respectively. The mean arterial pressure was 106.1 mmHg. 82.4% of the patients had hypertension. 71.5% used antihypertensive drugs and 49.5% of those used renin-angiotensin-aldosterone system (RAAS) blockers (angiotensin converting enzyme inhibitors or angiotensin receptor blockers). 13.2% of the patients had macroscopic hematuria and 16.7% had urinary tract stones. Liver cysts were found in 27.1% of the investigated patients. Out of patients, 11.2% had end stage renal disease and were treated with hemodialysis.Conclusion: This study showed that hypertension is the most common clinical finding in Autosomal dominantpolycystic kidney disease (ADPKD) patients and renin-angiotensin-aldosterone system (RAAS) blockers are widely used. The presence of potential risk factors such as age, smoking, clinical renal manifestations, hypertension and disease in family members should be questioned and investigated for the early diagnosis and treatment of this diseaseen_US
dc.identifier.dergipark379000en_US
dc.identifier.endpage18en_US
dc.identifier.issn2148-4724
dc.identifier.issn2548-0030
dc.identifier.issue1en_US
dc.identifier.startpage15en_US
dc.identifier.urihttps://dergipark.org.tr/tr/pub/tmsj/issue/34297/379000
dc.identifier.urihttps://dergipark.org.tr/tr/download/article-file/404620
dc.identifier.urihttps://hdl.handle.net/20.500.14551/6304
dc.identifier.volume2en_US
dc.language.isoenen_US
dc.publisherTrakya Üniversitesien_US
dc.relation.ispartofTurkish Medical Student Journalen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Başka Kurum Yazarıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAutosomal dominant polycystic kidney diseaseen_US
dc.subjecthypertensionen_US
dc.subjectangiotensin-converting enzyme inhien_US
dc.titleDemographic and Clinical Characteristics of Patients With Autosomal Dominant Polycystic Kidney Diseases in Istanbul Faculty of Medicineen_US
dc.typeArticleen_US

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