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Öğe Accessory mitral valve tissue: An overview of clinical and practical implications(Aves, 2021) Yalta, Kenan; Yetkin, Ertan; Yalta, Tulin; Taylan, Gokay[Abstract Not Available]Öğe Acute cardiovascular conditions in the setting of multiple sclerosis relapse: Practical implications(Polish Cardiac Soc-Polskie Towarzystwo Kardiologiczne, 2022) Polat, Mustafa Onder; Yalta, Kenan; Yalta, Tulin; Ozturk, Cihan[Abstract Not Available]Öğe Basal takotsubo syndrome: A multifaceted entity with potential implications(Elsevier Espana Slu, 2021) Yalta, Kenan; Ozturk, Cihan; Yalta, Tulin; Yetkin, Ertan[Abstract Not Available]Öğe Bone mineral density: A potential determinant of atherosclerotic plaque morphology in established coronary artery disease?(Elsevier Ireland Ltd, 2011) Sivri, Nasir; Yalta, Tulin; Yalta, Kenan; Yetkin, Ertan; Aksoy, Yuksel[Abstract Not Available]Öğe Cancer and takotsubo cardiomyopathy: More questions than answers(Elsevier Ireland Ltd, 2017) Yalta, Kenan; Yalta, Tulin[Abstract Not Available]Öğe Cardiac Biomarkers in the Setting of Asthma Exacerbations: a Review of Clinical Implications and Practical Considerations(Current Medicine Group, 2020) Yalta, Kenan; Yalta, Tulin; Gurdogan, Muhammet; Palabiyik, Orkide; Yetkin, ErtanPurpose of Review The present paper aims to highlight clinical implications of elevated cardiac biomarkers and associated myocardial dysfunction in a variety of cardiac and non-cardiac scenarios in patients with an asthma exacerbation, and to propose a basic algorithm for cardiovascular evaluation and triage (and hence, for further management) of these patients primarily based on evaluation of cardiac biomarkers along with basic diagnostic modalities and specific cardiac symptoms in the hospital setting. Recent Findings Elevation of cardiac biomarkers in the setting of an asthma exacerbation mostly signifies a new-onset subclinical myocardial dysfunction/injury generally associated with certain asthma-related factors including acute hypoxemia and bronchodilator therapy, and usually has a limited prognostic value in these patients. On the other hand, elevation of these biomarkers in patients with an asthma exacerbation might also denote a variety of certain life-threatening cardiac or non-cardiac conditions associated with significant myocardial dysfunction (acute coronary syndromes (ACSs), sepsis, etc.) that might be masked by the rampant course of the asthma exacerbation, and hence, might possibly go undetected potentially aggravating the prognosis in a portion of these patients. In patients with an asthma exacerbation, it seems imperative to timely diagnose and manage emerging diverse clinical conditions particularly through the guidance of cardiac biomarkers and associated myocardial dysfunction patterns in an effort to improve overall prognosis in these patients.Öğe Cardiac myxoma as a potential trigger of takotsubo cardiomyopathy: A brief review on mechanistic and clinical perspectives(Pagepress Publ, 2022) Yalta, Tulin; Yalta, Kenan; Ozkan, Ugur; Yetkin, ErtanIn clinical practice, cardiac myxomas constitute the majority of benign cardiac neoplasms, and might potentially present with a variety of embolic, obstructive as well as constitutional symptoms. On the other hand, these neoplasms might be potentially associated with the evolution of takotsubo cardiomyopathy (TTC) that is universally considered as a transient form of acute myocardial dysfunction. Accordingly, the present paper primarily aims to focus on potential mechanisms and associated clinical implications of TTC evolution in the setting of cardiac myxomas.Öğe Cardiac myxomas in an unusual location: A glimpse into their potential characteristics(Aves, 2021) Yalta, Kenan; Ozkan, Ugur; Yalta, Tulin; Yetkin, Ertan[Abstract Not Available]Öğe Cardiac pacing in patients with Fontan circulation: Further considerations(Polish Cardiac Soc-Polskie Towarzystwo Kardiologiczne, 2022) Yalta, Kenan; Gurdogan, Muhammet; Yalta, Tulin[Abstract Not Available]Öğe Chronotropic incompetence: An obscure cause of heart failure symptoms in survivors of critical diseases?(Elsevier Ireland Ltd, 2011) Yalta, Kenan; Yalta, Tulin; Sivri, Nasir; Aksoy, Yuksel; Yetkin, Ertan[Abstract Not Available]Öğe Co-existing cardiomyopathy in the setting of congenital coronary artery anomalies: Further insights into pathogenetic and clinical aspects(Polish Cardiac Soc, 2023) Yalta, Kenan; Yalta, Tulin; Yetkin, Ertan[Abstract Not Available]Öğe Combined Effectiveness of Honey and Immunonutrition on Bacterial Translocation Secondary to Obstructive Jaundice in Rats: Experimental Study(Int Scientific Information, Inc, 2018) Oguz, Serhat; Salt, Omer; Ibis, Abdil C.; Gurcan, Saban; Albayrak, Dogan; Yalta, Tulin; Sagiroglu, TamerBackground: Obstructive jaundice is a serious, life-threatening condition that can lead to death as a result of sepsis and multiorgan failure due to bacterial translocation. Treatment should be started as soon as possible after diagnosis. Material/Methods: Forty 24-week-old male Sprague Dawley rats, with an average weight of 250 g to 300 g, were included in this study. The rats were randomly placed into five groups, each group consisted of eight rats. The sham group underwent only common bile duct (CBD) dissection and no ligation was performed. CBD ligation was applied to the other groups. After the operation, one CBD group was fed with rat chow only, the others were fed with rat chow supplemented with honey, or immunonutrients, or honey plus immunonutrients. After 10 to 12 days, all rats were sacrificed; blood and tissue samples were collected for biochemical, microbiological, and histopathological evaluation. Results: In the groups that were fed with honey and immunonutrients, alanine aminotransferase (ALT) levels were de- creased significantly compared to the other groups. Statistically significant differences were detected in terms of bacterial translocation (BT) rates among liver and spleen samples, and laboratory values of serum, except for MLNs of the BDL+HI group, when compared to other groups. We found mean mucosal thickness of ileum samples have been improved notably in the BDL+HI group compared to the other groups, especially compared to the C/BDL group. Conclusions: Immunonutrition applied with honey had immunostimulant effects, decreased BT due to an additive effect, and had positive effects on intestinal mucosa.Öğe Combined Effects of Tauroursodeoxycholic Acid and Glutamine on Bacterial Translocation in Obstructive Jaundiced Rats(Galenos Publ House, 2013) Hatipoglu, Ahmet Rahmi; Oguz, Serhat; Gurcan, Saban; Yalta, Tulin; Albayrak, Dogan; Erenoglu, Cengiz; Sagiroglu, TamerBackground: Bacterial Translocation is believed to be an important factor on mortality and morbidity in Obstructive Jaundiced. Aims: We investigated the probable or estimated positive effects of tauroursodeoxycholic acid, which has antibacterial and regulatory effects on intestinal flora, together with glutamine on BT in an experimental obstructive jaundiced rat model. Study Design: Animal experimentation. Methods: Forty adult, male, Sprague Dawley rats were used in this study. Animals were randomised and divided into five groups of eight each: sham (Sh); control (common bile duct ligation, CBDL); and supplementation groups administered tauroursodeoxycholic acid (CBDL+T), glutamine (CBDL+G), or tauroursodeoxycholic acid plus glutamine (CBDL+TG). Blood and liver, spleen, MLN, and ileal samples were taken via laparotomy under sterile conditions for investigation of bacterial translocation and intestinal mucosal integrity and hepatic function tests on the tenth postoperative day. Results: There were statistically significant differences in BT rates in all samples except the spleen of the CBDL+TG group compared with the CBDL group (p=0.041, p=0.026, and p=0.041, respectively). Conclusion: It is essential to protect hepatic functions besides maintaining intestinal mucosal integrity in the active struggle against BT occurring in obstructive jaundice. The positive effect on intestinal mucosal integrity can be increased if glutamine is used with tauroursodeoxycholic acid, which also has hepatoprotective and immunomodulatory features.Öğe Copeptin (C-terminal provasopressin): A promising marker of arrhythmogenesis in arrhythmia prone subjects?(Elsevier Ireland Ltd, 2011) Yalta, Kenan; Sivri, Nasir; Yalta, Tulin; Geyik, Bilal; Aksoy, Yuksel; Yetkin, Ertan[Abstract Not Available]Öğe Copeptin and cardiovascular disease: A review of a novel neurohormone(Elsevier Ireland Ltd, 2013) Yalta, Kenan; Yalta, Tulin; Sivri, Nasir; Yetkin, ErtanNeurohormones (NHs) in the cascade of the arginine vasopressin (AVP) system have drawn particular attention in the recent years. Copeptin, the C-terminal portion of provasopressin, is a novel NH of the AVP system, and is known to be co-released with AVP from hypothalamus (neurohypophysis). As a surrogate marker of the AVP system, copeptin has gradually replaced AVP in several clinical studies largely due to its structural and methodological advantages. Copeptin has been regarded as a marker of non-specific stress response, and has also been suggested to have clinical implications in a variety of non-cardiovascular (pneumonia, sepsis, etc.) and cardiovascular conditions (heart failure and acute coronary syndromes (ACSs, etc.)). However, current data on relation of copeptin with other cardiovascular conditions (arrhythmias, etc.) are still insufficient. The present review primarily focuses on general features of copeptin, its general clinical implications, and specifically aims to cover its potential clinical value in a variety of cardiovascular conditions. (C) 2012 Elsevier Ireland Ltd. All rights reserved.Öğe Coronary Artery Ectasia is Associated with the Elevation of Mean Platelet Volume Regardless of an Existing Acute Coronary Syndrome(Aves, 2013) Sivri, Nasir; Yalta, Tulin; Yalta, Kenan; Altun, Armagan; Sut, Necdet; Yetkin, ErtanObjective: Elevated mean platelet volume (MPV) has been considered as an indicator of enhanced platelet reactivity. In several studies, MPV has been shown to be elevated in the setting of acute coronary syndromes (ACS) and coronary artery ectasia (CAE). In this study we aimed to investigate the potential effects of CAE on MPV regardless of an existing acute coronary syndrome (ACS). Methods: Two independent operator retrospectively reviewed the records of 12,724 patients who had previously (between the years 2000 and 2011) undergone coronary angiography in the catheterization laboratory. The present study comprised an overall 337 patients including 112 patients with stable coronary artery disease (CAD) (group 1), 112 patients with ACS (group 2) and 113 patients with isolated CAE (without ACS) (group 3). Results: The values of mean ages were 52.3 +/- 5.6; 52.5 +/- 5.7 and 49.7 +/- 3.8 in groups 1, 2 and 3, respectively (p< 0.001). Cardiovascular risk factors and hemoglobin levels did not significantly differ among groups. Mean platelet levels in groups 2 and 3 (244.8 +/- 28.3, 239.1 +/- 28.8, respectively) were found to be significantly lower than that of group 1 (276.4 +/- 0.69) (p< 0.001) whereas mean levels of MPV in groups 2 and 3 (9,09 +/- 1.07fL, 9.06 +/- 1.07fL, respectively) were found to be significantly higher than that of group 1 (8,56 +/- 1.28fL) (p< 0.001). Conclusion: Nothwithstanding the similar cardiovascular risk factors and admission patterns suggestive of a common etiopathological background among these 3 entities, MPV levels may be more likely to be elevated in the setting of ACSs and isolated CAE (regardless of an existing ACS) compared to stable CAD.Öğe Coronary slow flow: a potential prognostic marker correlating with the disease severity in renal failure?(Oxford Univ Press, 2010) Yalta, Kenan; Yilmaz, Mehmet Birhan; Yalta, Tulin; Sivri, Nasir; Refiker, Meltem[Abstract Not Available]Öğe Coronary syndrome Y: Should we focus more on extra-cardiac conditions including renal disease and its management?(Elsevier Ireland Ltd, 2011) Yalta, Kenan; Yilmaz, Mehmet Birhan; Yalta, Tulin; Sivri, Nasir; Yucel, Oguzhan[Abstract Not Available]Öğe Correspondence on Sodium-glucose co-transporter 2 inhibitor therapy: mechanisms of action in heart failure by Joshi et al(Bmj Publishing Group, 2021) Yalta, Kenan; Ozkan, Ugur; Yalta, Tulin[Abstract Not Available]Öğe Correspondence on Tetralogy of Fallot: management of residual hemodynamic and electrophysiological abnormalities by Zaidi(Bmj Publishing Group, 2022) Yalta, Kenan; Yalta, Tulin; Ozturk, Cihan[Abstract Not Available]