Cardiac Biomarkers in the Setting of Asthma Exacerbations: a Review of Clinical Implications and Practical Considerations
Küçük Resim Yok
Tarih
2020
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Current Medicine Group
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Purpose of Review The present paper aims to highlight clinical implications of elevated cardiac biomarkers and associated myocardial dysfunction in a variety of cardiac and non-cardiac scenarios in patients with an asthma exacerbation, and to propose a basic algorithm for cardiovascular evaluation and triage (and hence, for further management) of these patients primarily based on evaluation of cardiac biomarkers along with basic diagnostic modalities and specific cardiac symptoms in the hospital setting. Recent Findings Elevation of cardiac biomarkers in the setting of an asthma exacerbation mostly signifies a new-onset subclinical myocardial dysfunction/injury generally associated with certain asthma-related factors including acute hypoxemia and bronchodilator therapy, and usually has a limited prognostic value in these patients. On the other hand, elevation of these biomarkers in patients with an asthma exacerbation might also denote a variety of certain life-threatening cardiac or non-cardiac conditions associated with significant myocardial dysfunction (acute coronary syndromes (ACSs), sepsis, etc.) that might be masked by the rampant course of the asthma exacerbation, and hence, might possibly go undetected potentially aggravating the prognosis in a portion of these patients. In patients with an asthma exacerbation, it seems imperative to timely diagnose and manage emerging diverse clinical conditions particularly through the guidance of cardiac biomarkers and associated myocardial dysfunction patterns in an effort to improve overall prognosis in these patients.
Açıklama
Anahtar Kelimeler
Cardiac Biomarkers, Asthma, Asthma Exacerbation, Troponins, Natriuretic Peptides, N-Terminal Pro-Brain Natriuretic Peptide (NT-Probnp), Brain Natriuretic Peptide (BNP), Clinical Implications, Myocardial Dysfunction, Prognosis, Acute Myocardial-Infarction, Brain Natriuretic Peptide, Acute Coronary Syndromes, Takotsubo Cardiomyopathy, European-Society, Genetic-Basis, Task-Force, Dysfunction, Guidelines, Repolarization
Kaynak
Current Allergy And Asthma Reports
WoS Q Değeri
Q2
Scopus Q Değeri
Q1
Cilt
20
Sayı
6
