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Öğe Evaluation of tumor angiogenesis with contrast-enhanced dynamic magnetic resonance mammography(2003) Tuncbilek N.; Unlu E.; Karakas H.M.; Cakir B.; Ozyilmaz F.The goal of this research was to correlate dynamic magnetic resonance (MR) mammographic contrast enhancement and microvessel densities in breast masses. Forty-six female patients with breast masses detected by mammography and/or ultrasonography were included in the study. MR contrast enhancements of the lesions were investigated dynamically using axial three-dimensional fast low-angle shot sequences. After excisional biopsy or mastectomy, immunohistochemical staining with factor VIII-RA was performed, followed by microvessel density measurements. Contrast enhancement patterns in dynamic MR mammography were compared with microvessel density measurements using Student's t-test, Pearson's moment correlation coefficients, and one-way analysis of variance (ANOVA). Malignant lesions exhibited three different enhancement patterns: 1) a peak enhancement within 120 seconds (early phase), followed by a decrease in the delayed phase (25 cases); 2) an increase in the early phase, followed by a plateau in the delayed phase (9 cases); and 3) an increase throughout the examination without any peak (5 cases). In benign lesions, signal intensity did not exhibited a peak in five cases, whereas in two cases enhancement was increased in the early phase and made a plateau in the delayed phase. A significant correlation was found between microvessel density and the percentage of maximal signal increase following paramagnetic contrast administration (r= 0.322, p < 0.05). Dynamic enhancement patterns and rates of maximal signal increase predict microvessel density in breast malignancies and may possibly be used as prognostic indicators.Öğe Granulomatous mastitis mimicking breast carcinoma(2002) Çakir B.; Tuncbilek N.; Karakas H.M.; Unlu E.; Ozyilmaz F.[No abstract available]Öğe Hemobilia and occult cystic artery stump bleeding after a laparoscopic cholecystectomy: endovascular treatment with N-butyl cyanoacrylate.(2011) Cagli B.; Tuncel S.A.; Sengul E.; Temizoz O.; Unlu E.; Genchellac H.; Ozdemir H.Hemobilia is a rare phenomenon. In this case report we present an emergent transcatheter glue embolization (in which N-butyl cyanoacrylate is used as an embolizing agent) due to arteriobilary fistula occurred following the laparoscopic cholecystectomy in a 41-year-old woman.Öğe Joubert syndrome associated with total corpus callosum agenesis(Centauro SRL, 2006) Asil T.; Utku U.; Unlu E.; Balci K.Joubert syndrome was first described in 1969. It is a rare inherited disorder demonstrating one of the developmental defects of the cerebellar vermis. The main clinical signs of the syndome include developmental delay, hypotonia, ataxia, abnormal ocular movements and abnormal respiratory pattern of alternating episodic tachypnea-hyperpnea and apnea. Radiological findings comprise a midline cerebellar cleft in place of the vermis and a characteristic shape of the fourth ventricule. Associated supratentorial abnormalities such as callosal dysgenesis have been infrequently reported in patients with Joubert syndrome This report describes the clinical and neuroradiological findings of a rare patient presenting Joubert syndrome associated with total corpus callosum agenesis.Öğe Pleurosubcutaneous fistula presenting as lateral thoracic lump in an oncologic patient(2006) Unlu E.; Genchellac H.; Temizoz O.; Yoruk Y.; Demir D.We describe a case of pleurosubcutaneous fistula of the left thoracic wall in an oncologic female patient. She presented with left-sided pain and a chest wall mass bulge suspicious for breast neoplasm metastasis.Öğe The role of dynamic contrast-enhanced magnetic resonance imaging parameters in head-neck tumors(Centauro SRL, 2006) Unlu E.; Albayram S.; Temizoz O.; Caloglu M.; Tamer Y.We evaluated dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) in various head-neck masses, some of which are very rare tumors whose DCE-MRI have not been published to date. The purpose of this study was to investigate DCE-MRI in the differentiation of benign versus malignant lesions and to evaluate the DCE-MRI parameters most predictive for malignancy. Forty-one head-neck tumors including parotid gland tumors in 41 patients were examined at gadolinium-enhanced dynamic MR imaging. There were 26 malignant and 15 benign tumors. DCE-MR images were obtained between four and six minutes. Time-signal intensity curves (TICs) of the tumors on dynamic MR images were plotted, and then time of peak enhancement (Tpeak), and enhancement ratios (ER) with different times (such as ER30 ER60 ER90, ER120, ERmax) were also calculated. Data of the benign and malignant group with head-neck masses were compared by Mann-Whitney U-test. The mean values of time to peak (Tpeak) were found to be significantly shorter for the malignant group than the benign tumors (P<0.05). The mean enhancement rates of malignant lesions were ER30: 60.62±52.62, ER60: 105.65±56.26, ER90: 113.17±45.83, ER120: 116.59±46.75 and ERmax: 128.56±56.51 whereas the mean enhancement rate of benign lesions were ER30: 67.35±60.78, ER60: 79.79±63.33, ER90: 84.53±64.92, ER120: 88.41±67.07 and ERmax: 112.06±66.48. The mean signal intensity values of the 60th second (ER60) and 90th second (ER90) were significantly different from other values for predicting malignancy (P<.05). The parameters obtained from the time-signal intensity curve are important in differentiating benign and malignant enhancing lesions in dynamic head-neck MR imaging. DCE-MRI cannot replace standard MR imaging sequences for evaluating head-neck masses, but in addition to routine MR imaging it will improve differentiation between benign and malignant lesions.Öğe Seat belt injury of the breast: MR mammographic follow-up(Elsevier BV, 2003) Cakir B.; Tuncbilek N.; Unlu E.; Doganay L.Fat necrosis of the breast is a benign inflammatory process that most commonly occurs as the result of breast trauma. The radiographic and clinical significance of fat necrosis of the breast is that it may mimic a malignancy. We report mammographic, sonographic and MR imaging findings and evolution of the lesions located along the seat-belt line in a case of fat necrosis of the breast after a car accident. © 2002 Elsevier Science Ireland Ltd. All rights reserved.Öğe Segmental costovertebral anomaly presenting with horn-like appearance in the chest.(2010) Cagli B.; Unlu E.; Tuncel S.A.; Temizoz O.; Genchellac H.Several types of abnormalities of the ribs have been reported. Many of these anomalies usually result in the correct diagnosis thanks to the characteristic radiological appearances. But some of the anomalies are rare and it is important to recognize and get accustomed to differing appearances of these osseous abnormalities in order to differentiate the pathological processes and to diagnose the syndromes which may accompany rib anomalies. The localized costovertebral anomaly with horn-like appearance, which has not yet been described in literature, is presented in this paper.
