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Öğe Adding magnesium to lidocaine for intravenous regional anesthesia(Lippincott Williams & Wilkins, 2004) Turan, A.; Memis, D.; Karamanlyoglu, B.; Guler, T.; Pamukcu, Z.[Abstract Not Available]Öğe A comparison of the effect on gastric emptying of propofol or dexmedetomidine in critically ill patients(Cambridge Univ Press, 2006) Memis, D.; Dokmeci, D.; Karamanlioglu, B.; Turan, A.; Ture, M.Background: Propofol and dexmedetomidine are widely used for sedation in the intensive care unit yet there are limited data on its effects on gastric motility. In our preliminary study, we examined whether or not any effect of propofol and dexmedetomidine on gastric emptying is preserved in critically ill patients. Methods: Twenty-four critically ill, enterally fed adult patients each received enteral feeding via a nasogastric tube at 50 mL h(-1) throughout the 5-h study period. Either propofol 2 mg kg(-1) h(-1) (n = 12, Group P) or dexmedetomidine 0.2 mu g kg(-1) h(-1) (n = 12, Group D) was given intravenously over 5h. Gastric motility was measured indirectly by analysis of the absorption over time of 1.5 g of paracetamol administered into the stomach at the start of the study period. At the beginning and end of the study, residual gastric volume and pH of residual gastric fluid were measured. Results: Gastric residual volume measured at the end of propofol infusion (19.33 +/- 11.33) was found to be higher when compared with the volume measured before infusion (11.33 +/- 4.84) and after dexmedetomidine infusion (9.17 +/- 4.54). But, there was no difference between groups in gastric emptying time (AUC120 894.53 +/- 499.39 vs. 1113.46 +/- 598-09 propofol and dexmedetomidine groups, respectively). Conclusion: In our study, gastric residual volume measured at the end of propofol infusion was found to be higher when compared with the volume measured before infusion and after dexmedetomidine infusion. There was no difference between groups in gastric emptying time.Öğe Comparison of the effectiveness of delirium evaluation tools in intensive care patients: pre-deliric versions 1 and 2, E-pre-deliric and ICDSC(Verduci Publisher, 2023) Kucuk, O.; Memis, D.; Inal, M. T.; Turan, F. N.; Memis, I.OBJECTIVE: This study's objective was to compare the effectiveness of the delirium prediction model (predeliric) and the early prediction model (E-predeliric) in delirium prediction in an intensive care unit (ICU) according to the Intensive Care Delirium Screening Checklist (ICD-SC). Our aim was to determine these models' us-ability and cut-off values for ICU patients. PATIENTS AND METHODS: We classified the studied patients based on their highest ICDSC scores (tested twice daily) during ICU hospitaliza-tion. ICDSC scores of 4 or higher indicated positive results for delirium, whereas a score of 0 represented a negative result. We recorded the patients' demographic and clinical details and characteristics and calculated their E-predeliric and predeliric version 1 and version 2 scores. To evaluate the effectiveness of the models, we used receiver operating characteristic (ROC) curve analysis. RESULTS: Two hundred fifty patients (55.6% males, mean age 60.6 +/- 18.7 years) participated in this study. Their mean Acute Physiology and Chronic Health Evaluation II (APACHE-II) score was 17.0 +/- 9.1. Delirium was more common in men, patients of older ages, those with high APACHE-II scores, those who had undergone urgent admissions, those with histories of trauma, those with high urea or creatinine values and those who had undergone sedation or mechanical ventilation. Compared to patients who did not develop delirium, those who did had longer ICU stays and hospital stays, as well as greater mortality risk. The cutoff values for the patients' pre-deliric version 1, predeliric version 2 and E-pre-deliric scores were 38% [area under ROC (AUROC)=1], 22% (AUROC=1) and 28% (AUROC=1), respectively. CONCLUSIONS: This study is the first to compare the pre-deliric and E-pre-deliric prediction models. These models' validity and reliability were acceptable. They were clinically use-ful, and we identified their cut-off values. These models provide options for early detection of delirium and are easily applicable in the ICU.Öğe DETERMINING THE EFFICIENCY OF DIFFERENT PREOPERATIVE DIFFICULT INTUBATION TESTS ON PATIENTS UNDERGOING CAESAREAN SECTION(Lippincott Williams & Wilkins, 2016) Yildirim, I.; Inal, M. T.; Memis, D.; Turan, N.[Abstract Not Available]Öğe Effects of halothane, isoflurane, and sevoflurane on lipid peroxidation following experimental closed head trauma in rats(Wiley, 2008) Yurdakoc, A.; Gunday, I.; Memis, D.Background: In a rat closed head trauma model we examined both the time course of lipid peroxidation and the effects of halothane, isoflurane, and sevoflurane on it by analysis of malondialdehyde (MDA) formation. Methods: Animals were divided randomly into five groups: sham-operated (SO), n=18; control-closed head trauma to left frontal pole, n=18; closed head trauma model+halothane, n=18; closed head trauma model+isoflurane, n=18; and closed head trauma model+sevoflurane, n=18. Halothane, isoflurane, or sevoflurane were applied 15 min after trauma for 30 min. Rats were euthanized 1,3, and 5 h after the inhalation agents. Brain tissue samples were taken 5 mm from the left and right frontal poles. MDA was considered to reflect the degree of lipid peroxidation. Results: MDA concentrations were greater in the control, halothane, sevoflurane, and isoflurane groups than in SO animals (P < 0.001). No statistical difference between the hemispheres was found between the halothane, isoflurane, or sevoflurane groups, but MDA levels were lower with isoflurane than in the halothane, sevoflurane, and control groups at 1, 3, and 5 h (P < 0.001). MDA levels were higher as compared with the halothane and sevoflurane groups at 1 h but not at 3 or 5 h (P < 0.001). Conclusion: MDA levels with the isoflurane group were lower than in the other trauma groups, which suggest that isoflurane, given after closed head trauma, might be protective against lipid peroxidation of cerebral injury.Öğe Fatal aluminium phosphide poisoning(Lippincott Williams & Wilkins, 2007) Memis, D.; Tokatlioglu, D.; Koyuncu, O.; Hekimoglu, S.[Abstract Not Available]Öğe Gabapentin reduces cardiovascular responses to laryngoscopy and tracheal intubation(Lippincott Williams & Wilkins, 2006) Memis, D.; Turan, A.; Karamanlioglu, B.; Seker, S.; Ture, M.Background and objective: We have compared the effects of gabapentin on arterial pressure and heart rate at induction of anaesthesia and tracheal intubation in a randomized double-blind study. Methods: Ninety normotensive patients (ASA I) undergoing elective surgery were divided into three groups of 30 patients each. Patients received oral placebo (Group I), 400 mg of gabapentin (Group 11) or 800 mg of gabapentin (Group III) 1 h prior to surgery in, the operating theatre. After induction of anaesthesia heart rate and mean arterial pressure were recorded at baseline 1, 3, 5, 10 and 15 min after intubation. Results: Patients receiving placebo and 400 mg gabapentin showed a significant increase in blood pressure and heart rate associated with tracheal intubation compared to baseline levels and Group III. There was significant decrease in heart rate and arterial pressure in Group III after intubation 1, 3, 5 and 10 min (P < 0.001, P < 0.001, P < 0.05 and P < 0.05, respectively) compared to Groups I and II. Conclusion: Given 1 h before operation gabapentin 800 mg blunted the arterial pressure and heart rate increase in first 10min due to endotracheal intubation. Oral administration of gabapentin 800 mg before induction of anaesthesia is a simple and practical method for attenuating pressor response to laryngoscopy and tracheal intubation after standard elective induction.Öğe INTRAVENOUS PARACETAMOL REDUCED THE USE OF OPIOIDS AND EXTUBATION TIME AFTER MAJOR SURGERY IN INTENSIVE CARE UNIT(Springer, 2009) Memis, D.; Inal, M. T.; Kavalci, G.; Sezer, A.; Sut, N.[Abstract Not Available]Öğe Investigation of the effectiveness of prone ventilation in patients followed up for acute respiratory distress syndrome in the intensive care unit(Verduci Publisher, 2023) Yildirim, I.; Aydin, C.; Gultekin, A.; Inal, M. T.; Memis, D.OBJECTIVE: Prone positioning has been found to improve oxygenation in most patients with acute respiratory distress syndrome (ARDS). The study aimed to investigate the effectiveness of the prone position in patients with ARDS.PATIENTS AND METHODS: The prone position is one of the ventilator techniques included in recent guidelines for acute respiratory distress syndrome. This study was a retrospective evaluation of the records of 100 ARDS patients who were administered prone position mechanical ventilation in our intensive care unit. All patients were placed in the prone position for a total of 12 hours per day at 4-hour intervals (supine-prone) while admitted to the intensive care unit. RESULTS: This study included 100 participants. These patients were divided into two groups as survivors [(n=38, 16 females, 22 males, median age: 60 (24-86)] and non -survivors [(n=62, 19 females, 43 males, median age: 64 (21-93)], according to their intensive care follow-ups. Acute physiology and chronic health evaluation (APACHE) II score, the sequential organ failure assessment score (SOFA), and in-flammation markers were statistically significantly higher in the non-survivor group. Between the two groups, there was no statistically signif-icant difference in terms of fundamental characteristics. In the sub-group evaluation of the subjects in patients with ARDS with and with-out novel coronavirus disease 2019 (COVID-19) groups, the patients in the COVID-19 (+) group were older, had shorter hospital stays, had higher APACHE II and SOFA scores, and higher rates of cardiovascular disease and sepsis.CONCLUSIONS: Applying prone-position mechanical ventilation in the cohorts of our patients with ARDS resulted in a demonstrable significant improvement in the oxygenation levels of our patients.Öğe Late-onset pulmonary edema due to propofol(Wiley-Blackwell, 2008) Inal, M. T.; Memis, D.; Vatan, I.; Cakir, U.; Yildiz, B.Pulmonary edema after the administration of propofol has rarely been reported. In this case report, we describe pulmonary edema due to the administration of propofol during a Cesarean section and while in the intensive care unit. The skin tests demonstrated strong positive weal and flare reactions to propofol. The patient was treated successfully with mechanical ventilatory support. This report emphasizes that this fatal complication may be seen with propofol and underlying mechanisms and therapeutic approach are discussed.Öğe 'Multimodal' approach to management of prostate biopsy pain and effects on sexual function: efficacy of levobupivacaine adjuvant to diclofenac sodium - a prospective randomized trial(Wiley-Blackwell Publishing, Inc, 2010) Aktoz, T.; Kaplan, M.; Turan, U.; Memis, D.; Atakan, I. H.; Inci, O.P>We assessed the analgesic efficacy of levobupivacaine when administered as an adjuvant to diclofenac sodium in prostate biopsy pain management and effects of prostate biopsy on sexual function. Ninety patients underwent transrectal ultrasound (TRUS)-guided biopsy of the prostate and were randomly assigned to three groups: group D received diclofenac sodium suppository; Group L received periprostatic injection of levobupivacaine; group DL received diclofenac suppository and levobupivacaine in addition. Patients were asked to use a visual analogue scale score (VAS) questionnaire about pain after 10 core prostate biopsy. Sixty-two patients reported to be prostate cancer-free underwent further evaluation with the International Index of Erectile Function-5 (IIEF-5) questionnaire at 1 and 3 months after biopsy. Mean pain scores during prostate biopsy were significantly lower in group DL and were superior to the group L and group D (P < 0.001). Mean IIEF-5 score prior to biopsies was significantly higher when compared with the mean IIEF-5 score 1 month after biopsy (P < 0.0001). Mean IIEF-5 scores 1 month after biopsy were significantly lower when compared with the mean IIEF-5 scores 3 months after biopsy (P = 0.002). TRUS-guided prostate biopsies have a statistically significant impact on short-term erectile function, but this difference is not clinically significant; however, medium-term erectile function is not affected both statistically and clinically.Öğe The prevention of pain from injection of propofol by dexmedetomidine and comparison with lidocaine(Lippincott Williams & Wilkins, 2004) Turan, A.; Memis, D.; Kaya, G.; Karamanlyoglu, B.; Pamukcu, Z.[Abstract Not Available]
