Yazar "Erdogan, Okan" seçeneğine göre listele
Listeleniyor 1 - 20 / 20
Sayfa Başına Sonuç
Sıralama seçenekleri
Öğe Acute myocardial infarction due to disulfiram (antabus)-alcohol interaction(Springer, 2006) Altun, Gurcan; Altun, Armagan; Erdogan, Okan[Abstract Not Available]Öğe Alternative site of ventricular pacing: fight ventricular outflow tract(Galenos Yayincilik, 2007) Erdogan, OkanThe main reasons for traditional right ventricle apical pacing were first, the ease of implantation and second, the stability of passive-fixation leads in the apical trabeculae. However, apart from some specific diseases like hypertrophic cardiomyopathy, apical pacing often results in substantial functional, hemodynamic, electrical, and structural changes as previously demonstrated in many studies. Only in recent years, interest in the use of alternate pacing sites has developed. Right ventricular outflow tract is the preferred site of pacing because of its potential advantages such as ease of application, better hemodynamics, synchronous activation, less myocardial perfusion defects than apical pacing. The present review article comprehensively discusses this novel technique in terms of its beneficial effects compared to apical pacing and as an alternative method for biventricular pacing.Öğe Anomalous origin of the right coronary artery from the left anterior descending artery in a patient with single left coronary artery: A rare coronary artery anomaly and review of the literature(Elsevier Ireland Ltd, 2008) Erdogan, Okan; Buyuklu, Mutlu; Aktoz, MeryemA 44-year-old woman with hypertension was admitted because of recent onset chest pain. Coronary angiography revealed an anomalous right coronary artery originating as a separate branch from the left anterior descending artery. Associated with the present case all published case reports were thoroughly investigated and presented as a review of the literature. (C) 2007 Elsevier Ireland Ltd. All rights reserved.Öğe Comparison of antihypertensive efficacy of carvedilol and nebivolol in mild-to-moderate primary hypertension: a randomized trial(Aves Yayincilik, 2011) Erdogan, Okan; Ertem, Bulent; Altun, ArmaganObjective: The aim of the present study is to compare the antihypertensive effects of carvedilol and nebivolol in mild to moderate hypertensive patients. Methods: It is a prospective; placebo-controlled, cross-over, double-blind, randomized, single-center clinical trial. Patients (n=20) who were first diagnosed with mild to moderate systemic hypertension according to mean ambulatory blood pressure measurements > 130/85 mmHg and no previous antihypertensive therapy were prospectively enrolled into the study. After 10 days of placebo run-in period, they were randomized within the same group as cross-over design to one month carvedilol 25 mg and one month nebivolol 5 mg regimen given once daily in the morning. The primary outcome variables were systolic and diastolic blood pressures determined by 24-hour ambulatory blood pressure measurements. Mutlivariate analysis of variance for repeated measurements with 3x2 factorial design was used for statistical analysis of results. Results: The study group consisted of 6 women and 14 men whose mean age was 42.9 +/- 12.8 years (range 19-63 years). Mean heart rate was significantly decreased after commencing both carvedilol (70.2 +/- 5.2 bpm) and nebivolol (64.9 +/- 3.9 bpm) treatments compared to placebo (78.8 +/- 5.2 bpm) (p<0.05). Both carvedilol (133.8 +/- 9/86.6 +/- 8.6 mmHg) and nebivolol (134 +/- 8.7/85.6 +/- 7.4 mmHg) significantly decreased mean systolic and diastolic blood pressures compared to placebo (143.9 +/- 8.9/94.4 +/- 9.2 mmHg), respectively (p<0.05). However, there was no significant difference in decreasing either systolic or diastolic blood pressure between nebivolol and carvedilol therapies (p>0.05). No side effects were recorded during both carvedilol and nebivolol treatments. Conclusion: Although both carvedilol and nebivolol effectively decreased blood pressure compared to placebo, they showed similar efficacy for lowering blood pressure. (Anadolu Kardiyol Derg 2011; 11: 310-3)Öğe Contrast-induced nephropathy: preventive and protective effects of melatonin(Wiley, 2006) Gazi, Sabri; Altun, Armagan; Erdogan, OkanInfusion of contrast agents increases osmotic load, viscosity, hypoxemia of the renal medulla and renal free radical production through post-ischemic oxidative stress. The present experimental study sought to determine whether melatonin, because of its anti-oxidant properties might have a preventive and protective role against the development of contrast-induced nephropathy (CIN). Twenty-four adult male rats were divided into four experimental groups: healthy control rats (CR), rats with CIN (CINR), rats with CIN pretreated with melatonin (CINR1M), and rats with CIN pre- and post-treated with melatonin (CINR2M). In CINR, both serum creatinine (Cr) level and fractional excretion of sodium (FE-Na) significantly increased, whereas Cr clearance decreased at post-CIN compared with pre-CIN period. Rats in CINR1M did not show any improvement in renal function. Cr clearance decreased, whereas both serum Cr level and FE-Na increased in rats pretreated with melatonin. In contrast, significant improvements were observed in CINR2M. Serum Cr and Cr clearance did not change, whereas FE-Na significantly reduced in rats pre- and post-treated with melatonin. In conclusion, the present experimental study clearly demonstrated the preventive and protective role of melatonin against the development of CIN.Öğe Demonstration of a persistent left superior vena cava by transthoracic echocardiography using agitated saline injection(Pulsus Group Inc, 2007) Erdogan, Okan; Aksu, Feyza; Birsin, Atilla[Abstract Not Available]Öğe Diagnostic Approach to a Case with Aortic Dissection(Aves, 2010) Aktoz, Meryem; Erdogan, Okan; Tatli, ErsanWithout a dear diagnosis, patients with aortic dissection often die before presentation to the hospital. Keeping a high clinical index of suspicion is mandatory for the accurate and rapid diagnosis of aortic dissection. The choice of the diagnostic modality mainly depends on the availability of the diagnostic tools and the experience of the physicians at the given institution.Öğe Diagnostic value of plasma fibronectin level in predicting the presence and severity of coronary artery disease(Springer, 2009) Ozcelik, Fatih; Erdogan, Okan; Aktoz, Meryem; Ekuklu, Galip; Tatli, Ersan; Demir, MuzafferThe relation between fibronectin and coronary artery disease (CAD) according to previous study results is controversial. The aim of the present study is to investigate the predictive value of fibronectin in determining the presence and severity of CAD. Patients with stable angina (n = 62) who had angiographically documented CAD, and control patients (n = 31) who had normal coronary angiograms, were included in the study. Plasma fibronectin levels were determined in all patients. Plasma fibronectin level (milligrams per liter) in patients with CAD was higher than normal controls (364.2 +/- 171 vs 265.1 +/- 135.5, p = 0.006). The severity of CAD determined according to Gensini score and fibronectin level did not show any correlation (r = 0.13, p = 0.311). If fibronectin level 240 mg/l was determined as cutoff, it showed 76% sensitivity, 46% specificity, 46% negative predictive value, and 72.3% positive predictive value for predicting CAD. The present study showed that plasma fibronectin level in CAD is significantly higher than normal control subjects. However, it has no role in predicting the severity of CAD.Öğe Early effects of low versus high dose atorvastatin treatment on coagulation and inflammation parameters in patients with acute coronary syndromes(Elsevier Ireland Ltd, 2008) Ordulu, Emine; Erdogan, OkanAim: To demonstrate the efficacy of low or high dose statin treatment on C-reactive protein (CRP), von Willebrand Factor (vWF) and Factor VII (FVII) during the first two weeks of acute coronary syndromes. Patients and methods: Patients with acute coronary syndromes (n=60) were randomly and prospectively allocated in three different groups. They received 10 mg (low dose), 80 mg (high dose) of atorvastatin and placebo for two weeks. Plasma levels of CRP, vWF and FVII were compared at baseline, first and second weeks of treatment. Results: Low dose therapy resulted in non-significant elevation of CRP at first week, although high dose therapy significantly lowered its level (7.75 +/- 3.57 vs 7.13 +/- 2.95; p=.04). Both low and high dose therapies effectively suppressed the production and elevation of vWF in contrast to placebo (121.15 +/- 31.99 vs 139.7 +/- 28.53; p=.04). Conclusions: High dose atorvastatin significantly decreased CRP during the early days of acute coronary syndromes. Although vWF significantly increased in placebo group, both low and high dose atorvastatin treatments effectively suppressed its increased production. (c) 2007 Elsevier Ireland Ltd. All rights reserved.Öğe Electrocardiographic prediction of left ventricular geometric patterns in patients with essential hypertension(Elsevier Ireland Ltd, 2007) Aktoz, Meryem; Erdogan, Okan; Altun, ArmaganBackground: The present study sought to determine the diagnostic value of electrocardiographic voltage criteria in predicting geometry patterns in patients with essential hypertension. Methods: Patients with essential hypertension (n=125) according to left ventricular mass index and relative wall thickness as determined by echocardiography were assigned in the following groups: normal geometry (N, n=50), concentric remodeling (CR, n=12), concentric hypertrophy (CH, n=28) and eccentric hypertrophy (EH, n=35). Each patient underwent 12-lead ECG followed by determination of conventional voltage criteria as well as peak to peak QRS lengths in each lead. Results: Voltage criteria such as Sokolow-Lyon, Cornell, Cornell product > 2440, DIR+D3S > 25 mm, and AVL R > 11 mm could not significantly predict and discriminate geometric patterns of LVH. However, they all were very specific (range 97-100%) and showed very high positive predictive values (range 94-100%) for detecting abnormal geometry. DI peak > 12 mm had a sensitivity 61%, specificity 67%, accuracy 63%, positive predictive value 81%, and negative predictive value 42% in predicting to differentiate CH from CR. Sum of the calculated values from the peak of the R to the nadir of the S wave in all limb leads > 60 mm had sensitivity 68%, specificity 75%, accuracy 70%, positive predictive value 86% and negative predictive value 50% in predicting to differentiate CH from CR. Conclusions: Conventional ECG voltage criteria could not significantly discriminate specific geometry patterns observed in patients with essential hypertension. (c) 2006 Elsevier Ireland Ltd. All rights reserved.Öğe Hotter monitoring in the prognosis of sudden cardiac death(Galenos Yayincilik, 2007) Erdogan, OkanThe frequency and rate of either premature ventricular complexes or nonsustained ventricular tachycardia episodes as well as any transient conduction disturbance in a given patient with high risk features for sudden cardiac death (SCID) can be established with Holter monitoring and risk for future cardiac arrhythmic events predicted with reasonable probability. With the aid of published medical literature the present article discussed the role of nonsustained ventricular tachycardia and frequent premature ventricular complexes recorded with long-term Holter electrocardiography in predicting SCID associated with common cardiac disorders such as coronary heart disease, dilated and hypertrophic cardiomyopathy.Öğe Intercostal muscle twitching: An unusual manifestation of extracardiac stimulation related to right ventricular outflow tract pacing(Pulsus Group Inc, 2007) Erdogan, OkanThe present case report describes a patient who underwent Successful dual-chamber pacemaker implantation with active ventricular lead fixation at a high septal region in the right ventricular outflow tract. Unexpectedly, stimulation at a high output in the right ventricular outflow tract caused an unusual extracardiac Stimulation, specifically, intercostal Muscle twitching.Öğe Long-term safety and efficacy of right ventricular outflow tract pacing in patients with permanent pacemakers(Aves Yayincilik, 2008) Erdogan, Okan; Aktoez, Meryem; Altun, ArmaganObjective: The aim of the present study was to investigate long-term safety and change in pacing parameters of right ventricular outflow tract (RVOT) pacing. Methods: This prospectively designed controlled clinical study comprised patients in Group 1 (n= 16) and Group 2 (n= 16) who were paced in RVOT and right ventricular apex (RVA), respectively, and were selected from patients with permanent pacemakers who were routinely followed up at our pacemaker clinic. Commercially available active fixation leads were used in all patients. Pacing parameters were compared at implant and long-term follow-up visits. Statistical analyses were performed using Pearson Chi-Square, nonparametric Mann-Whitney U and Wilcoxon Signed Ranks tests. Results: The mean duration of follow-up was 38.3 +/- 18.0 months for RVOT and 30.4 +/- 20.0 months for RVA (p=0.255). Impedance values, pacing thresholds and R wave amplitudes measured at implant and last pacemaker check did not significantly differ between RVOT and RVA pacing groups. There was no lead dislodgment or any other procedure related complication during follow-up. Conclusion: Right ventricular outflow tract pacing site is safe and pacing impedance and threshold values are comparable with conventional RVA pacing in the long-term. (Anadolu Kardiyol Derg 2008; 8: 350-3)Öğe Oral verapamil effectively suppressed complex ventricular arrhythmias and unmasked U waves in a patient with Andersen-Tawil syndrome(Churchill Livingstone Inc Medical Publishers, 2008) Erdogan, Okan; Aksoy, Alper; Turgut, Nilda; Durusoy, Elcim; Samsa, Murat; Altun, ArmaganAndersen-Tawil syndrome (ATS) is a rare, heterogeneous, autosomal dominant, or sporadic disorder characterized by the clinical triad of periodic paralysis, dysmorphic features, and ventricular arrhythmias such as bidirectional ventricular tachycardia (BVT). We present a case of an elderly patient with ATS whose symptomatic ventricular arrhythmias including BVT were effectively suppressed by oral verapamil therapy. (C) 2008 Elsevier Inc. All rights reserved.Öğe Pacemaker lead failure due to crush injury(Galenos Yayincilik, 2007) Erdogan, Okan; Aktoz, Meryem[Abstract Not Available]Öğe Parachute mitral valve abnormality and bicuspid aortic valve in an asymptomatic adult patient(Elsevier Science Inc, 2008) Erdogan, Okan; Aktoz, Meryem[Abstract Not Available]Öğe Persistent coronary occlusion after myocardial infarction(Massachusetts Medical Soc, 2007) Erdogan, Okan[Abstract Not Available]Öğe A rare coexistence of complete atrioventricular block and preexcitation in an elderly symptomatic patient(Lippincott Williams & Wilkins, 2008) Erdogan, OkanThe present case report describes an elderly patient with complete atrioventricular nodal block coexisting with intermittent preexcitation, which resulted in paroxysmal complete loss of atrioventricular conduction and symptoms. The patient ended up with pacemaker implantation without requiring ablation of accessory pathway.Öğe Right ventricular outflow tract pacing: Relation of high to low synchronous ventricular activation with cardiac memory(Elsevier Ireland Ltd, 2008) Erdogan, Okan; Aktoz, MeryemCardiac memory is usually observed after right ventricular apical pacing and considered to be related to alter asynchronous activation by apical pacing. However, it is not known whether it occurs by unaltered high to low synchronous ventricular activation by right ventricular outflow tract (RVOT) pacing. We present here a case with dual chamber pacemaker whose ventricular lead positioned in the RVOT and developed cardiac memory immediately after ventricular pacing had stopped and the underlying sinus rhythm resumed. (c) 2007 Elsevier Ireland Ltd. All rights reserved.Öğe Urgent approach to a patient presenting with type A aortic dissection associated with cardiac tamponade(Aves Yayincilik, Ibrahim Kara, 2007) Ordulu, Emine; Erdogan, Okanmale patient aged 68 years, arrived to the emergen-cyoutpatient clinic with a transient loss of conscience, following acute onset chest and back pain. Physical examination of the. patient revealed cyanosis in the head and neck region and distension of neck veins. A dense effusion around the cardiac spaces was observed during the echocardiographic examination. Thoracoabdominal computed tomography with contrast did not reveal findings supporting dissection. The clinical condition of the patient improved significantly after the drainage of 650 ml of fluid. On repeat echocardiography, a double contour in the ascending aorta, 2 cm proximal to -the valvular level and separated by a hypodense area was observed. The patient was operated and a Dacron graft was inserted to the ascending aorta along the 6 cm segment starting from 2 cm proximal to the valvular level. The patient was discharged upon full recovery.
