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Öğe The effect of aminophylline administration on 99mTc-MIBI lung and liver uptake in patients with or without myocardial ischemia(Ediciones Doyma, S.L., 2000) Yüksel M.; Durmus Altun G.; Altun A.; Berkarda S.This work aims to analyze the influence of aminophylline in the pulmonary and hepatic uptake of 99mTc-methoxyisobutil isonitrile ( 99mTc-MIBI). 72 patients were studied and a myocardial perfusion (MPS) single photon emission computed tomography (SPECT) with 99mTc-MIBI was carried out after the administration of dipyridamole. According to the MPS, the patients were classified into 2 groups: Group A: 45 patients without myocardial ischemia and Group B: 27 with ischemia. Each group was divided into 2 subgroups according to whether they had (I) or had not (II) received intravenous aminophylline. The dipyridamole was administered for 4 minutes at a dose of 0.56 mg/kg. If the patients presented any complication, intravenous aminophylline was administered. At 30 minutes p.i., planar images were obtained during a scintigraphy in the interior projection after the injection of 99mTc-MIBI. The regions of interest in the heart, hepatic cupula, and most active area of the left lung were outlines and the activity rates were calculated: lung/heart (LHR) and liver/heart (LivHR). No statistically significant differences were observed in the uptake of 99mTc-MIBI between subgroups I and II. However, the LHR rates in both subgroups were significantly lower in the patients with normal myocardial perfusion than in the patients with ischemia: LHR group A1 vs B1: 0.32 ± 0.08 vs 0.36 ± 0.06, p = 0.03; group AII vs BII 0.31 ± 0.07 vs 0.35 ± 0.07, p = 0.01 respectively. In conclusion, the administration of aminophylline, after the infusion of dipyridamole for MPS, does not modify the pulmonary or hepatic uptake of 99mTc-MIBI.Öğe The relation of functional independent measurement and ambulation with bone mineral density in patients with stroke(2011) Murat S.; Özdemir F.; Kabayel D.D.; Kasapo?lu M.; Kokino S.; Berkarda S.Objective: The aim of this study was to investigate the relationship between loss of functions and bone mineral density (BMD) in hemiplegic patients after stroke. Material and Method: 41 patients were evaluated. The Brunnstrom values, the Functional Independent Measurement (FIM) and the Functional Ambulation Categories (FAC) values were recorded. BMD measurements were evaluated with dual-energy X-ray absorbtiometry (DXA). Results: BMD decrease was significantly greater on the paretic side compared with the nonparetic side. Patients who had not ambulated lost of their BMD in the paretic side and the loss was significantly higher than those who had ambulated. There was a positive correlation between FIM score and BMD values in the affected side. Conclusion: Our results suggest that the rapidity of the BMD loss is correlated to the functional independent and ambulation categories in poststroke hemiplegic patients.