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Öğe A case of tenoxicam induced generalized (multifocal) bullous fixed drug eruption(2008) Arican Ö.; Ürün M.Fixed drug eruption is a common cutaneus reaction characterized by the formation of localized erytema, hyperpigmentation and blisters that recur at the same cutaneous site or sites each time when the drug is ingested. Rarely it can be disseminated. Fixed drug eruption has been reported with many drugs. The most frequently causative agents are various antibiotics, analgesic/anti-inflammatory drugs, barbiturates, laxatives that contain phenolphthalein, metronidazole, oral contraceptives and quinine. Herein, we report a case of a generalized bullous fixed drug eruption developing in a 61-year-old female patient after using a suppository containing tenoxicam for the purpose of analgesia. We present the case because of its rarity to emphasize the clinical importance of the differential diagnosis.Öğe Empact syndrome: Case report(2010) Arican Ö.; Gediz Gürsel Y.; Alkurt M.Intracranial malignancies often complicated by seizure activity. For this reason, phenytoin is typically employed as a prophylactic anticonvulsant. However, severe cutaneous adverse effects may occur in these patients. Especially in patients who received cranial radiotherapy, starting from the radiation field to the whole body can be seen erythema multiforme-like lesions. Recently, in the patients with brain metastases, using phenytoin and taking cranial radiation developing erythema multiforme major is defined as EMPACT (Erythema Multiforme associated with Phenitoin And Cranial radiation Therapy) syndrome. So far, in the national and international medical literature, a few case reports about this new syndrome have been presented. The pathogenesis of EMPACT syndrome has not been completely understood but a combination of metabolic and immunologic mechanisms may be involved. In this article, we also present the case of a 53-year-old female with EMPACT syndrome. Here, during cranial radiotherapy, especially before prophylactic anticonvulsant therapy utilizing phenytoin, the benefits of patient-focused thinking and the importance of multidisciplinary approach are asked to be highlighted. Clinical findings, pathogenesis, differential diagnosis and treatment of the disease were also discussed with new information. Copyright © 2010 by Türkiye Klinikleri.Öğe Öğe Milkers nodule: Answer of the last issue's case questions(2011) Arican Ö.; Uzunali E.[No abstract available]Öğe Primary cutaneous follicle center lymphoma: Case report(2010) Arican Ö.; Önver N.; Özpuyan F.Cutaneous lymphomas are rare dermatological disorders and usually thought to be in extranodal non-Hodgkin lymphoma group. Cutaneous B-cell lymphoma (CBCL) is characterized with proliferation of monoclonal B lymphocytes and localized only to the skin for a long time. Primary CBCLs constitute less than 25% of all cutaneous lymphomas. Primary cutaneous follicule center cell lymphoma (PCFCCL) is the tumour of neoplastic follicule center cells. In all types of CBCLs, red-brown colored nodules and tumors are mostly encountered and plaque lesions are rarely seen. We present here, a 38-year-old man diagnosed with PCFCCL because it rarely seen and to emphasize the importance of early diagnosis in long-termed resistant lesions. Copyright © 2010 by Türkiye Klinikleri.Öğe Öğe Three cases of tinea incognito(2009) Arican Ö.; Gürsel Y."Tinea incognito" is a dermatophytic infection which modifies typical clinical presentation due to improper use of topical or systemic corticosteroids. In this report, we present three cases who had been treated with topical corticosteroid as a result of incorrect diagnosis. The first case, a 30-year-old male patient complained of localized, erythematous, scaling papules and plaques on his genitocrural crease and umbilical region for four months. The second case, a 40-year-old male patient had generalized, erythematous plaques with papules and pustules, and macular hyperpigmentation for one month. The third case, a 23-year-old male patient had erythematous macules with papules on his malar areas for three months. In all presented cases, direct microscopic examination was positive and, in the first and second cases, the fungal cultures were positive for Trichophyton rubrum. The lesions also showed complete resolution with antimycotic treatment. In this report, we have reviewed the recent medical literature about "tinea incognito". © Medical Journal of Trakya University. Published by Ekin Medical Publishing. All rights reserved.Öğe What is your diagnosis? [10.5336/medsci.2009-14422](Turkiye Klinikleri, 2010) Pişkin S.; Arican Ö.; Uzunali E.; Yalçin Ö.[No abstract available]
