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Öğe A case of cebocephaly associated with abnormal genitalia(Elsevier Ireland Ltd, 2007) Duran, Ridvan; Aladag, Nukhet; Vatansever, Ulfet; Acunas, Betul; Puyan, Fulya Oz; Varol, Fusun G.Holoprosencephaly is frequently accompanied by midline facial abnormalities such as hypotelorism, cyclopia, etmocephaly, and cebocephaly. Cebocephaly is a very rare congenital anomaly combining alobar holoprosencephaly, ocular hypotelorism, and a proboscis-like nose with single nostril. There is only one cebocephaly case with abnormal genitalia. We report to our knowledge the second case of cebocephaly associated with abnormal genitalia in the relevant literature. (C) 2007 Elsevier Ireland Ltd. All rights reserved.Öğe Case of The Month(Aves, 2005) Vatansever, Ulfet; Duran, Ridvan; Acunas, Betul[Abstract Not Available]Öğe A case report: 13q21-qter deletion with digital anomalies, duodenal atresia and anal atresia(Springer, 2015) Ozen, Yasemin; Gurkan, Hakan; Ozbek, Ulfet Vatansever; Atli, Emine Ikbal; Eker, Damla; Acunas, Betul[Abstract Not Available]Öğe Changes in parents' attitudes towards childhood vaccines during COVID-19 pandemic(Wiley, 2023) Duran, Sedef; Duran, Ridvan; Acunas, Betul; Sahin, Erkan MelihBackground: Concerns about the safety and adverse reactions of rapidly-developed vaccines against COVID-19 contributed to parents' vaccine hesitancy and this situation created an opportunity for anti-vaccine campaigners. The aim of this study was to examine the changes in parents' attitudes towards childhood vaccines during COVID-19 pandemic. Methods: In this cross-sectional study, parents of children who applied to the outpatient clinic of pediatric department of Trakya University Hospital, Edirne, Turkiye, between August 2020 and February 2021 were recruited into two study groups according to COVID-19 peak time in Turkiye. Group 1 included parents of children who applied after first peak of the COVID-19 pandemic and Group 2 included parents of children who applied after second peak. The World Health Organization 10-item Vaccine Hesitancy Scale (WHO-VHS) was applied to each group. Results: A total of 610 parents agreed to participate in the study. Group 1 and 2 consisted of 160 and 450 parents, respectively. While the number of parents who were hesitant about childhood vaccines was 17 (10.6%) in Group 1, it was 90 (20%) in Group 2. A statistically significant difference was found between the two groups ( p = 0.008). The (WHO-VHS) mean +/- SD score was found to be higher in Group 2 (23.7 +/- 6.9) than Group 1 (21.3 +/- 7.3) (p < 0.001). The WHO-VHS-mean +/- SD scores of parents who experienced COVID-19 infection themselves or their family or acquaintances were significantly lower than those who did not (20.0 +/- 6.5 vs. 24.7 +/- 6.9) (p < 0.001). Conclusions: The hesitant attitudes towards childhood and COVID-19 vaccines were low in parents who directly or indirectly experienced COVID-19 or were worried about the devastating effects of this disease. However, it was shown that as the COVID-19 pandemic progressed, parents' hesitations towards childhood vaccines increased.Öğe Comparison of respiratory morbidity in late preterm infants and intrauterine growth retarded infants at school-age(Marmara Univ, Fac Medicine, 2022) Us, Mahmut Caner; Vatansever, Ulfet; Duran, Ridvan; Acunas, BetulObjective: We aimed to determine respiratory morbidity of late pretenn infants versus infants with intrauterine growth retardation (IUGR) at school-age. Patients and Methods: Late preterm appropriate for gestational age (AGA) infants (34-36, 6/7 weeks) (Group 1), IUGR infants (Group 2), extremely preterm AGA (Group 3) and term AGA infants (Group 4) born between 2004 and 2008 were included in this case-control study and assessed for respiratory morbidity at school-age. We evaluated the impact of late preterm compared with IUGR and term gestation on respiratory morbidity by using validated American Thoracic Society - Division of Lung Diseases (ATS-DLD-78-C) and the International Study of Asthma and Allergies in Childhood (ISAAC) questionnaires. Questionnaires on wheezing, infectious respiratory morbidity, and physician-diagnosed asthma panels were constituted and groups were compared. Results: A total of 160 patients were enrolled in the study and 97 (60.6%) of them were boys. Respiratory morbidities at school-age were found to be significantly higher in both late preterm and IUGR groups when compared to term controls. Each weekly increase in gestational age reduced the risk for wheezing episodes (OR perGW:0.82,95%CI:0.71-0.97, p:0.02). Regarding infectious respiratory morbidities, there was a significant increase when the number of people living at home increased (OR perperson:1.79,95%CI:1.12-2.87, p:0.01), and a decrease in female gender (OR:0.41,95%CI:0.17-0.99, p:0.04) and in the week of gestation (OR perGW:0.84,95%CI:0.71-1.00, p:0.04). Atopic dermatitis (OR:5.26,95%CI:1.57-17.69, p<0.01) and maternal asthma (OR:5.38,95%CI:1.17- 24.60, p:0.03) history were found to be risk factors for asthma. Conclusion: Being IUGR may be an important risk factor for respiratory morbidity at school-age. Further studies are needed on this subject.Öğe Comparison of sleep problems between term and preterm born preschool children(Elsevier, 2020) Durankus, Ferit; Ciftdemir, Nukhet Aladag; Ozbek, Ulfet Vatansever; Duran, Ridvan; Acunas, BetulObjectives: Sleep disorders are common problems among all age groups. If sleep problems detected in childhood are not resolved successfully, they become sleep disorders and a chronic state. In this study, we aimed to compare sleep problems between preterm-born and term-born preschool-age children. Methods: In the cross-sectional study, children were grouped according to whether they were born preterm or at term. The preterm group included 137 children aged four to six years. The control group comprised 145 age-matched term-born preschool children. The prenatal, natal, demographical, and clinical characteristics of preterm- and term-born preschool-age children were compared. The Children's Sleep Habits Questionnaire (CSHQ) was used to identify sleep problems. The total score and subscores of the CSHQ were compared between the groups. Results: The percentage of gastroesophageal reflux (GER) symptoms and obstructive sleep apnea (OSA) symptoms were significantly higher in the preterm group. According to the cutoff point of the CSHQ, 97 children in the preterm group (70.8%) and 88 children in the control group (60.7%) had a sleep disorder. The total score of the CSHQ was significantly higher in the preterm group compared with the control group; however, the scores of the subscales were similar between the groups. In the regression analysis, a significant association was found between being born preterm and having sleep disorder (beta = 0.308, OR = 1.36, p = 0.04). Conclusions: Our study reported a high percentage of sleep problems in preterm-born preschool children. We suggest that prematurity is associated with sleep problems even if the etiology of sleep problems is heterogeneous. Symptoms regarding GER and OAS should be investigated, and precautions, such as prohibiting maternal cigarette smoking, should be taken in preterm infants. (C) 2020 Elsevier B.V. All rights reserved.Öğe Comparison of temporal artery, nasopharyngeal, and axillary temperature measurement during anesthesia in children(Elsevier Science Inc, 2012) Sahin, Sevtap Hekimoglu; Duran, Ridvan; Sut, Necdet; Colak, Alkin; Acunas, Betul; Aksu, BurhanStudy Objective: To evaluate the accuracy and precision of a new, noninvasive infrared thermometer applied to the temporal artery. Design: Prospective randomized study. Setting: Trakya University Hospital. Patients: 60 ASA physical status 1 and 2 children undergoing surgery. Interventions: During anesthesia, temperature measurements were recorded with three different techniques: temporal artery, nasopharynx, and axillary temperature. Measurements: Temperatures measured from the nasopharynx, temporal artery, and the axilla were recorded at 15-minute intervals for the first hour, then at 30-minute intervals until the completion of surgery. During each measurement, heart rate and midarterial pressure were recorded. Main Results: There were no statistically significant differences between temperatures recorded at the temporal artery and nasopharynx at 15, 30, 45, 60, 90, and 120 minutes, and the completion of surgery. Axillary temperatures were statistically lower than those recorded at the nasopharynx and the temporal artery (P < 0.001). Bland-Altman plots showed a correlation of temperature measurements between the temporal artery and nasopharyngeal methods. The axillary method had a lower correlation with the temporal artery and the nasopharyngeal methods. Conclusions: The temporal artery thermometer is a substitute for the nasopharyngeal thermometer for core temperature measurement during anesthesia in children. (C) 2012 Elsevier Inc. All rights reserved.Öğe Congenital and Perinatal Cytomegalovirus Infections in the Neonatal Period: Case Series(Aves Yayincilik, Ibrahim Kara, 2020) Ciftdemir, Nukhet Aladag; Acunas, BetulObjective: Cytomegalovirus infection when diagnosed in the first three weeks of life is generally accepted to be indicative of a congenital or vertical infection, whereas when cytomegalovirus infection is diagnosed after the first three weeks of life, it is generally considered as perinatal or horizontal infection. Since diagnosis of either a congenital or perinatal cytomegalovirus infection is challenging, as well as their treatment, this study aimed to address the issues about the diagnosis and treatment of congenital/perinatal cytomegalovirus infection by presenting a series of infants followed-up in our neonatal intensive care unit. Material and Methods: Medical records of newborn infants with congenital/perinatal cytomegalovirus infection who were admitted to our level ill neonatal intensive care unit between August 2015 and May 2018 were evaluated retrospectively. Only infants who received cytomegalovirus-specific therapy were included. Results: Out of 1039 infants admitted to the neonatal intensive care unit during the study period, 8 (0.8%) were diagnosed and treated for congenital/perinatal cytomegalovirus infections. All of them were preterm infants. Four infants found to be CMV positive during the first 21 days of life were diagnosed as congenital cytomegalovirus infection, while a perinatal and congenital infection differentiation could not be made in the rest of the patients. Anemia (75%), thrombocytopenia (62.5%) and hearing loss (62.5%) were the most common findings in patients with congenital/perinatal infection. None of the infants had chorioretinitis. Two infants (25%) with microcephaly had intracranial calcifications. Sepsis-like findings were present in three very preterm infants (37.5%). Cytomegalovirus-IgM was positive in all 8 infants with infection; however, serum CMV-DNA was positive in seven of them. All infants with moderate to severe symptoms were treated with ganciclovir and/or valganciclovir. Viral load decreased dramatically at the end of the treatment period. Conclusion: Cytomegalovirus infection, either congenital or perinatal, is a greater risk especially for preterm infants who may warrant and benefit from newborn cytomegalovirus screening, early detection, and effective antiviral treatment.Öğe Cranial mr venography findings of severe hypernatremic dehydration in association with cerebral venous thrombosis in the neonatal period(Taylor & Francis Inc, 2007) Duran, Ridvan; Aladag, Nukhet; Vatansever, Uelfet; Temizoz, Osman; Genchallac, Hakan; Acunas, BetulSevere neonatal hypernatremia is an important electrolyte disorder that has serious effects on the central nervous system, including brain edema, intracranial hemorrhage, hemorrhagic infarct, and thrombosis. Cerebral venous thrombosis is relatively rare in severe neonatal hypernatremic dehydration. The English literature contains only a few reports of the cranial radiological findings in severe neonatal hypernatremia. The authors report cranial MR venography findings of a newborn infant with severe hypernatremic dehydration. To the best of their knowledge, this is the first such report in the English literature.Öğe Diagnostic and therapeutic approach in newborns with ambiguous genitale with disorder of sex development: consensus report of Turkish Neonatal and Pediatric Endocrinology and Diabetes Societies(Turkish Pediatrics Assoc, 2018) Cetinkaya, Merih; Ozen, Samim; Uslu, Sinan; Gonc, Nazli; Acunas, Betul; Akinci, Aysehan; Satar, MehmetDisorders of sex development are defined as conditions in which the chromosomal, gonadal, and anatomic sex is discordant. Patients usually present with atypical appearing genitalia. In the assessment of neonates with disorders of sex development, first, it is important to determine whether this situation requires prompt evaluation, and then the karyotype, hormone levels, and underlying etiology should be determined as soon as possible. All these procedures should be performed in the guidance of a multidisciplinary team in reference centers. As the physical examination of the infant is extremely important, the physcian should suspect and then perform a detailed history and physical examinationi and lastly plan the required laboratory and imaging procedures for the definite diagnosis. It is important not to be hurried in the choice of sex. The aim of this article, which includes the diagnostic and therapeutic approaches in infants with ambiguous genitalia, was to provide a common practice for all pediatricians.Öğe Eating Behaviors of Late and Moderately Preterm Infants at Two Years of Age and Their Associations With Mothers' Mental Health(Lippincott Williams & Wilkins, 2021) Duran, Sedef; Duran, Ridvan; Acunas, Betul; Cesur, Gulay; Ciftdemir, Nukhet AladagObjectives: Preterm infants are at high risk for nutritional difficulties during the neonatal period and early childhood. Long-term nutritional difficulties contribute to unbalanced food intake and growth disorders and are the source of major emotional stress for the family. The aim of this study is to investigate the eating problems of late and moderately preterm (LMPT) infants at the age of 2 years, and to examine the association of these problems with the mental status of their mothers. Methods: In this cross-sectional study, group 1 included LMPT infants born between 32 and 36 + 6 weeks of gestation and Group 2 included term infants born between 37 and 41 + 6 weeks of gestation. Children's Nutrition Difficulties Questionnaire and 21-item Depression Anxiety and Stress Scales (DASS 21) were used for the detection of nutritional difficulties of infants and mothers' mental health status. Results: Groups 1 and 2 were consisted of 79 LMPT and 38 term infants, respectively. Late and moderately preterm infants were found to have a lower drive-to-eat and food repertoire scores as well as lower appetite and food enjoyment than term infants. Pickiness and food neophobia were found to be higher in LMPT infants than term infants. The DASS-21 scores of the mothers of the LMPT infants were higher than those of the term ones. Conclusions: These findings suggest that LMPT infants have more nutritional difficulties at the age of 2 years than term infants and their mothers exhibit more emotional distress than term infant's mothers.Öğe Effect of neonatal resuscitation courses on long-term neurodevelopmental outcomes of newborn infants with perinatal asphyxia(Wiley-Blackwell, 2012) Duran, Ridvan; Gorker, Isik; Kucukugurluoglu, Yasemin; Ciftdemir, Nukhet Aladag; Ozbek, Ulfet Vatansever; Acunas, BetulBackground: In previous studies, it has been demonstrated that Neonatal Resuscitation Program (NRP) courses improve the early outcomes of infants with perinatal asphyxia, but there has been no evidence to demonstrate the effect of NRP on long-term outcomes of perinatal asphyxia. The goal of the present study was to determine the effect of NRP courses on the long-term neurodevelopmental outcome of perinatal asphyxia. Methods: This prospective study included infants referred to the Neonatal Unit during the years 2003-2005. Those patients who were referred before NRP courses (pretraining period) were designated as group 1, those who were referred after the first NRP course (transition period) as group 2, and those who were referred after the second NRP course (post-training period) as group 3. Neurodevelopmental outcomes were assessed and compared at 4-6 years of age. Results: The study involved 40 patients: 23 in group 1, nine in group 2 and eight in group 3. The number of patients who had been diagnosed with cerebral palsy was 13 in group 1, two in group 2, and one in group 3, which was a significant decrease. The number of patients with seizures and electroencephalography abnormality was 12 and 14 in group 1, three and two in group 2, and one and one in group 3, respectively, which was also a significant decrease. Conclusions: NRP courses have positive effects on short-term as well as long-term neurodevelopmental outcomes of infants with perinatal asphyxia. Further studies are required to determine the effects of NRP courses on minor deficits, such as cognitive and behavioral disturbances.Öğe The effect of prenatal breast-feeding and breast-milk training given to expectant mothers on the behaviour of breast-feeding(Turkish Pediatrics Assoc, 2011) Onbasi, Senay; Duran, Ridvan; Ciftdemir, Nukhet Aladag; Vatansever, Ulfet; Acunas, Betul; Sut, NecdetAim: At present, training given during pregnancy has been shown to affect the beginning, percentage and duration of breast-feeding. The present study aims to inform expectant mothers about breast-milk and breast-feeding via a prenatal training and to emphasize the advantages of the training. Material and Method: Trainings on and breast-milk were held for the pregnant womens on two days in a week. Each expectant mother was given prenatal training once. Data were collected via a questionnaire composed of 42 questions about breast-milk and breastfeeding. Statistical 7.0 package was used for statistical analysis. All numeric values were expressed as mean +/- SD and n (%). A p value of < 0.05 was considered statistically significant. This study was approved by the Trakya University Local Ethics Committee. Results: A total of 190 mothers, 90 in training group and 100 in control group were included in the study. A significant difference in the breast-feeding percentage was found in the first six months. The bottle feeding was found to be the case of breast-feeding for less than six months. Conclusions: It is concluded in the present study that the percentage and duration of feeding only with breast-milk could be increased if pregnant women are given training about breast-milk. (Turk Arch Ped 2011; 46: 75-80)Öğe The effects of noise reduction by earmuffs on the physiologic and behavioral responses in very low birth weight preterm infants(Elsevier Ireland Ltd, 2012) Duran, Ridvan; Ciftdemir, Nukhet Aladag; Ozbek, Ulfet Vatansever; Berberoglu, Ufuk; Durankus, Ferit; Sut, Necdet; Acunas, BetulObjective: Preterm infants are exposed to loud noises during their stay in the neonatal intensive care unit which can lead to physiologic and behavioral alterations and even hearing loss. The use of earmuffs can reduce sound level and these changes. The objective of the present study is to evaluate the effectiveness of the earmuffs in preterm infants solely cared for in closed incubators. Methods: A comparative prospective study comprising 20 clinically stable preterm infants weighing less than 1500 g cared in closed incubator was conducted. Preterm infants acted as their own controls whereby they were observed without earmuffs (Group 1) for 2 days and with earmuffs (Group 2) on consecutive 2 days. The preterm infants' physiologic responses and Anderson Behavioral State Scoring System (ABSS) scores were assessed over 30 s every 2 h for 8 h during daytime for 4 days. Results: Out of 20 preterm infants, 6 were male and 14 female with a mean birth weight of 1220 +/- 209 g, gestational age of 29.9 +/- 2.1 weeks. The total number of measurements was 320. The mean ABSS scores of Group 1 and 2 were 3.07 +/- 1.1 and 1.34 +/- 0.3, respectively. Statistically significant difference was noted between the means of ABSS scores (p < 0.001). Preterm infants with earmuffs (87.5%) were more frequently observed in a quiet sleep state of ABSS compared with those without earmuffs (29.4%). Conclusions: Noise level reduction was associated with significant improvement in behavioral states of ABSS. We suggest that noise reduction in preterm infants with earmuffs is helpful by improving sleep efficiency and increasing time of quiet sleep. (C) 2012 Elsevier Ireland Ltd. All rights reserved.Öğe Factor V Leiden mutation, deficiency of antithrombin III and elevation of factor VIII in a child with ischemic stroke(Elsevier Science Bv, 2006) Duran, Ridvan; Biner, Betul; Demir, Muzaffer; Celtik, Coskun; Karasalihoglu, Serap; Acunas, BetulA 4-year-old boy was admitted with left hemiplegia. Thrombophilia marker examination resulted with factor V Leiden mutation heterozygosity, a deficiency of antithrombin III and a high level of factor VIII. Cranial computed tomography scan revealed an ischemic infarct in the region of right anterior cerebral artery. In the literature, combinations of multiple thrombophilia risk factors that trigger cerebral ischemic stroke in children have been emphasized. To our knowledge, this is the first child with these combinations of thrombophilia risk factors and ischemic stroke to be reported in the literature. (c) 2006 Elsevier B.V. All rights reserved.Öğe Gastric pneumatosis intestinalis(Lippincott Williams & Wilkins, 2006) Duran, Ridvan; Vatansever, Ulfet; Aksu, Burhan; Acunas, Betul[Abstract Not Available]Öğe Intestinal perforation: Rewiev of our experience in the neonatal period(Aves, 2007) Duran, Ridvan; Vatansever, Ulfet; Aksu, Burhan; Inan, Mustafa; Acunas, BetulAim: Despite rapid advances in neonatal intensive care, intestinal perforation (IP) has remained a major and life- threatening complication in neonates. Spontaneous intestinal perforation (SIP) is a recently defined entity, which is mostly seen in very low birthweight (VLBW) newborn infants. We want to report and discuss etiology, clinical features, and outcome of our IP cases. Material and Method: Charts of thirteen infants with IP was reviewed in terms of gender, birth weight, gestational age, day of perforation, diagnosis, location of perforation, type of surgery performed, and clinical outcome. Results: There were nine boys and four girls. Eight of them were preterm. Mean perforation time was day nine postnatally. 11 infants had the causes of IP including meconium ileus (n= 6), necrotizing enterocolitis (NEC) (n= 4), esophageal atresia (n= 1), following malrotation surgery (n= 1) and, three of them were on mechanical ventilator support. Two VLBW infants developed IP following oral ibuprofen administration. Perforation occurred in the distal ileum in the majority of infants. Conclusions: We found that essentially NEC, meconium ileus, and mechanical ventilation were associated with intestinal perforations and SIP following oral ibuprofen administration was observed in two preterm infants.Öğe Knowledge gained and retained by neonatal nurses following neonatal resuscitation program course(Aves, 2007) Duran, Ridvan; Aladag, Nukhet; Sen, Filiz; Vatansever, Ulfet; Acunas, BetulAim: The aim of our study was to evaluate the knowledge gained and retained by neonatal nurses following neonate resuscitation program (NRP) course. Material and Method: The study comprised 30 neonatal nurses. A 3-day course was held in the Department of Pediatrics, Medical School, Trakya University. A written test with 80 questions derived from the standard test contained in the American Heart Association and the American Academy of Pediatrics Neonatal Resuscitation Manual was given to the neonatal nurses before, at the end and six months after the course. Results: The percentages of correct answers significantly improved immediately after the course (% 33,6 +/- 10; % 92,4 +/- 6,1). The percentages at the six months follow-up-course test were significantly reduced as (% 56,2 +/- 12,6) compared to the post-course results, but remained higher with respect to pre-course results. The knowledge gained and retained had increased significantly after the NRP course particularly in the administration of medications and fluids step. Conclusions: These data suggest that a NRP course may be required prior the end of the usual two-year certification period of NRP courses especially one year after the course.Öğe Meningococcemia: Different Serotypes in the Same Region(Ankara Microbiology Soc, 2020) Aladag Ciftdemir, Nukhet; Duran, Ridvan; Vatansever Ozbek, Ulfet; Hancerli Torun, Selda; Acunas, Betul; Unal Sahin, NuriyeMeningococcal infections are important health problems causing high morbidity and mortality. Neisseria meningitidis have 13 serogroups. A, B, C, Y and W135 are the most common causes of invasive disease among those serogroups. The distribution of the serogroups differs according to the geographical regions and the age groups. In this case report, two cases of meningococcemia infected with serogroup C and Y of N.meningitidis rarely seen in our country were presented. First case was a two and a half year-old female patient who has admitted to our pediatric emergency unit with fever and rash spreading from lower extremities to her body. The patient had diffuse purpuric rash with generalized weakness and tendency to sleep at admission. The patient has been suspected as meningococcemia because of the skin rash, tendency to sleep and hypotension. Antibiotics treatment was started immediately and lumber puncture was performed. In blood tests, leukocyte count: 3600/mm(3) (61% neutrophils), hemoglobin: 11.1 g/dl, platelet count: 127.000/mm(3), C-reactive protein: 10 mg/dl, erythrocyte sedimentation rate: 6 mm/hour, prothrombin time: 28.8 seconds (normal value= 11-16), prothrombin activity: 36%, international normalized ratio (INR): 2.13 (normal value= 1-1.5), activated partial thromboplastin time: 57.7 seconds (normal value= 25-35 sec), fibrinogen: 246 mg/di (normal value= 200-400 mg/dl) and in cerebrospinal fluid protein: 21 mg/dl and glucose: 62 mg/dl were found. There were eight cells in the microscopic examination. Skin rashes were increased and the patient became hypotensive. No microorganisms were isolated in blood and cerebrospinal cultures. N.meningitidis serogroup C was isolated from the cerebrospinal fluid of the patient using polymerase chain reaction (PCR). The patient suffered from immune-mediated arthritis in the sixth day of treatment and nonsteroidal anti-inflammatory drugs were given. The patient has recovered with antibiotics, fresh frozen plasma and inotropic treatment. Second case was a 13 year-old male patient who has admitted three days after the first case with a pre-diagnosis of malignancy because of pancytopenia and fever. The patient had generalized weakness and a few petechial purpuric rashes at the facial region at admission. After the admission general status of the patient has worsened rapidly and he has died as a result of cardiovascular arrest. Blood tests in admission showed leukocyte count: 6000/mm(3) (79% neutrophils), hemoglobin: 17.3 mg/dl, platelet count: 16.000/mm(3), C-reactive protein: 8.63 mg/dl, prothrombin time: 92.6 seconds, prothrombin activity: 10%, INR: 6.78, activated partial thromboplastin time: 231.5 seconds. Cerebrospinal fluid obtained from postmortem lumbar puncture showed no growth (protein: 95 mg/dl, glucose: 35 mg/dl) and N.meningitidis serogroup Y was detected by PCR. Two meningococcemia cases caused by two different serogroups which are rarely seen in our region in recent years were presented at the same time period in the same hospital. This case report pointed out that surveillance has a great importance in such diseases.Öğe Neurodevelopmental and psychiatric assessments at corrected age of 1-3 years in very preterm infants(Turkish Pediatrics Assoc, 2011) Gorker, Isik; Vatansever, Ulfet; Acunas, BetulAim: To assess the neurodevelopmental and psychiatric outcomes of very preterm vs preterm infants at 1-3 years of corrected age. Material and Method: Between years 2005-2008, premature infants followed-up in the NICU designated as Group 1 (<32 wks;n=36) were evaluated in comparison to Group 2 (33-37wks; n=56) with the approval of Ethics Committee (TUTFEK 2008/083) in terms of neurodevelopmental and psychiatric development by using Denver developmental screening test, the brief infant toddler social emotional assessment-childcare provider version. Mothers' psychiatric symptoms were assessed by the brief symptom inventory. Socioeconomic status was determined by using SES scale. t-test or Mann-Whitney U tests, chi-square and Spearman tests were used for statistical analysis. Results: In Group 1, paternal education level and psychodevelopmental score was lower than group 2, abnormal outcome in Denver developmental test was more frequent. Psychiatric problem score was higher in boys, whereas psychodevelopmental score was higher in girls. Psychosocial developmental score was lower in those infants with intraventricular hemorrhage and this score showed positive correlation with Denver developmental test results. There was no difference between the two groups in terms of brief symptom inventory. Conclusions: Although very preterm infants more frequently showed abnormal neuropsychological development, they were not significantly different with regard to psychiatric problems. Girls were more advantegous than boys in terms of psychodevelopment. We conclude that these findings should be validated by larger and further studies. (Turk Arch Ped 2011; 46: 280-5)
